Figure 4

T-helper-associated cytokines and chemokines. The concentration (pg/ml) of (A) lymphocyte activator IL7 (left), Th17-associated cytokine IL17 (right) (B) Th2-associated cytokine IL4 and chemokine CCL11/Eotaxin (left and right respectively) and (C) Th1-associated cytokines and chemokines IFNγ (top left), MIG/CXCL9 (top right), and IP10/CXCL10 (bottom left) were measured in sera from controls (n = 3), afebrile patients (n = 3) and febrile patients ~15 hours after the onset of fever (n = 3) using a multiplex bead ELISA. Levels of IP10 were also assessed by a single-plex bead ELISA (C, bottom right) in controls (n = 13), afebrile patients (n = 8) and febrile patients 12 hours before, ~15 hours and ~120 hours after the onset of fever (-12 (n = 1), ~15 (n = 3), ~120 (n = 1)). Measured quantities are reported in Additional File 4, Table S3.