Table 2 Methodological assessment of clinical trials
From: The role for osmotic agents in children with acute encephalopathies: a systematic review
Study | Fisher 1992 [26] | Namutangula 2007 [27] | Peltola 2007 [28] | Simma 1998 [29] |
|---|---|---|---|---|
Was the assignment to treatment groups truly random? | Y | Y | Y | Y |
Were participants blinded to treatment allocation? | N | Y | Y | Y |
Was allocation to treatment groups concealed from the allocator? | U | Y | Y | N |
Were the outcomes of people who withdrew described and included in the analysis? | Y | Y | Y | Y |
Were those assessing outcomes blind to the treatment allocation? | U | Y | Y | N |
Were the control and treatment groups comparable at entry? | N | Y | Y | Y |
Were the groups treated identically other than for the named interventions? | Y | Y | Y | Y |
Were outcomes measured in the same way for all groups? | Y | Y | Y | Y |
Were outcomes measured in a reliable way? | Y | Y | Y | Y |
Was appropriate statistical analysis used? | Y | Y | Y | Y |