Table 9 ROC curve analysis statistics for combination of sICAM-1 + hsCRP measurements
Infected | |||||
|---|---|---|---|---|---|
| Â | All | Early onset | Late Onset | Preterm | Term |
sICAM-1 + hsCRP | n = 71 | n = 12 | n = 59 | n = 60 | n = 11 |
AUC | 0.81 | 0.56 | 0.68 | 0.82 | 0.65 |
sensitivity | 78.9% | 33.3% | 59.3% | 85.0% | 45.4% |
specificity | 75.9% | 96.0% | 69.4% | 70.0% | 90.6% |
Positive predictive value | 67.5% | 57.1% | 76.1% | 68.0% | 62.5% |
Negative predictive value | 85.0% | 90.1% | 51.0% | 86.2% | 82.9% |
Culture positive infection | |||||
| Â | All | Early onset | Late Onset | Preterm | Term |
sICAM-1 + hsCRP | n = 39 | n = 5 | n = 34 | n = 32 | n = 7 |
AUC | 0.79 | 0.583 | 0.68 | 0.82 | 0.57 |
sensitivity | 71.8% | 40.0% | 52.9% | 85.0% | 71.4% |
specificity | 75.0% | 95.2% | 76.7% | 70.0% | 58.3% |
Positive predictive value | 43.7% | 33.3% | 58.1% | 68.0% | 25.0% |
Negative predictive value | 90.8% | 96.3% | 75.0% | 86.2% | 91.3% |