A) Culture isolation of Mycobacterium tuberculosis from patient specimen OR B) Radiological findings consistent with TB AND 2 or more of: 1) a positive TST; 2) confirmed contact with an infectious case; 3) a specimen positive on microscopy or molecular testing; 4) CSF findings consistent with TBa OR C) All of: 1) Radiological findings consistent with TB; 2) no diagnosis more likely than TB; and 3) clinical improvement on antitubercular therapy AND one or more of: 1) a positive TST; 2) confirmed contact with an infectious case; 3) a specimen positive on microscopy or molecular testing; 4) CSF findings consistent with TBa |