From: Irisin combined index to diagnose central precocious puberty in girls: a cross-sectional study
groups | CPP group (n = 43) | PPP group (n = 44) | Normal control group (n = 24) | Z-value | P |
---|---|---|---|---|---|
CA [years, M (P25, P75 )] | 8.42(7.58,8.77) | 7.63(6.92,8.17) | 7.67(6.33,8.8.25) | - | < 0.001 |
Height (cm,‾χ ± s) | 136.42 ± 9.11 | 128.73 ± 8.55 | 122.78 ± 12.17 | - | < 0.001 |
HAZ (‾χ ± s) | 1.31 ± 1.03 | 1.10 ± 1.08 | 0.32 ± 1.20 | - | 0.002 |
Weight [kg, M (P25, P75 )] | 32.85(27.00,41.45) | 27.95(24.08,30.00) | 24.25(21.05,28.25) | - | < 0.001 |
WAZ [M (P25, P75 )] | 1.46(0.57,2.09) | 1.08(0.44,1.54) | 0.09(-0.54,1.31) | - | 0.005 |
BMI (‾χ ± s) | 18.15 ± 2.56 | 17.13 ± 2.20 | 16.04 ± 2.00 | - | 0.001 |
BAZ [M (P25, P75 )] | 1.03(0.14,1.48) | 0.78(-0.25,1.29) | 0.10(-0.57,0.79) | - | 0.029 |
Waist circumference [cm, M (P25, P75 )] | 65.50(58.00,69.00) | 57.60(53.60,63.05) | - | -3.023 | 0.003 |
Hip circumference [cm, M (P25, P75 )] | 77.30(68.20,83.00) | 69.25(64.28,73.00) | - | -3.757 | < 0.001 |
Bone age [years, M (P25, P75 )] | 11.00(8.83,12.00) | 8.83(7.83,8.83) | - | -5.795 | < 0.001 |
Bone age index [M (P25, P75 )] | 0.26(0.19,0.31) | 0.13(0.05,0.25) | - | -4.373 | < 0.001 |
IGF-1 [ng/ml, M (P25, P75 )] | 252.80(189.20,408.80) | 177.45(147.85,214.23) | - | -4.194 | < 0.001 |
B-LH ≥ 0.3 IU/L [n (%)] | 36(83.72) | 3(6.82) | - | - | < 0.001 |
B-FSH [IU/L, M (P25, P75 )] | 3.38(2.37,4.72) | 1.76(1.21,2.29) | - | -5.773 | < 0.001 |
Estradiol ≥ 5 Pg/ml [n (%)] | 40(93.02) | 20(45.45) | - | - | < 0.001 |
PRL [ng/ml, M (P25, P75 )] | 12.70(7.93,24.30) | 11.20(7.82,15.98) | - | -0.785 | 0.432 |
Testosterone ≥ 0.087 nmol/l [n (%)] | 13(30.23) | 3(6.82) | - | - | 0.005 |
P- LH [IU/L, M (P25, P75 )] | 12.25(7.12,19.33) | 3.07(2.93,3.67) | - | -3.873 | < 0.001 |
P-FSH [IU/L, M (P25, P75 )] | 12.15(9.72,14.70) | 9.77(9.10,11.80) | - | -1.383 | 0.167 |
peak LH /FSH ratio [M(P25, P75)] | 1.24(0.54,1.76) | 0.31(0.25,0.37) | -3.430 | 0.001 | |
Uterine volume [cm3, M (P25, P75 )] | 2.10(1.90,2.28) | 1.10(0.80,1.50) | - | -7.325 | < 0.001 |
Ovarian volume [cm3, M (P25, P75 )] | 2.35(1.75,3.45) | 2.8(1.60,3.00) | - | -2.566 | 0.010 |
Glu[mmol/l, M(P25, P75)] | 4.66(4.56,4.81) | 4.95(4.71,5.31) | - | -2.031 | 0.042 |
TC[mmol/l, M(P25, P75)] | 3.76(3.30,4.50) | 3.76(3.52,4.13) | - | -0.412 | 0.680 |
TG[mmol/l, M(P25, P75)] | 0.81(0.60,1.20) | 0.78(0.68,1.02) | - | -0.074 | 0.941 |