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Table 2 Univariate and multivariate binary regression analysis of predictors of HP

From: Nomogram for predicting early hypophosphatemia in term infants

 

Univariate analysis

 

Multivariate analysis

 

p Value

OR(95%CI)

 

β

Wald

p Value

OR(95%CI)

Maternal diabetes

0.001

5.91(1.991–17.545)

 

1.608

7.482

0.006

4.994(1.577–15.809)

Hypertensive disorders of pregnancy

0.987

1.019(0.112–9.236)

     

Treat with magnesium sulphate

0.79

1.362(0.14-13.266)

     

Intrauterine infection

0.19

1.855(0.737–4.669)

     

Placental abruption

0.046

6.304(1.036–38.363)

 

0.624

0.381

0.537

1.867(0.257–13.533)

Meconium-stained amniotic fluid

0.335

0.363(0.046–2.849)

     

Forceps delivery

0.832

1.088(0.5-2.368)

     

Male

0.002

2.215(1.333–3.682)

 

0.846

9.346

0.002

2.331(1.355–4.011)

Cesarean delivery

0.001

2.329(1.411–3.845)

 

0.762

7.792

0.005

2.142(1.255–3.657)

Neonatal asphyxia

0.715

1.2119(0.433–3.384)

     

Twin pregnancy

0.158

0.241(0.033–1.737)

     

Small for Gestational Age

<0.001

4.167(2.169,8.006)

     

Birth weight(g)

0.001

0.999(0.999-1.0)

 

-0.001

12.499

<0.001

0.999(0.999-1)

Gestational age(week)

0.610

0.954(0.796–1.144)

     

Maternal age(year)

0.954

0.998(0.933–1.068)

     

The time of pregnancy

0.322

0.877(0.677–1.136)

     

The time of delivery

0.316

0.723(0.383–1.363)

     

PROM(h)

0.143

0.981(0.956–1.006)

 

-0.14

1.17

0.279

0.986(0.96–1.012)

25-VitD3(ng/ml)

0.992

1(0.963–1.038)

     

Calcium(mmol/L)

0.221

2.1(0.640–6.891)

     

Magesium(mmol/L)

0.081

0.119(0.011–1.298)

 

-2.658

4.455

0.035

0.07(0.006–0.827)

ALP(U/L)

0.486

1.002(0.996–1.008)

     
  1. Abbreviations OR, odds ratio; CI, confidence interval
  2. Estimated odds ratios based on logistic regression. Significant variables were selected using the “Enter” logistic regression model. According to the multivariate analysis, the risk of HP with maternal diabetes, male, cesarean delivery was 4.994, 2.331, 2.142 times increased respectively. The likelihood of hypophosphatemia rose by 93% for every 1 mmol/L decrease in serum magnesium. Meanwhile, incidence of hypophosphatemia rose by 0.1% for every 1 gram decrease in body weight