Table 2 Comparison of risk factors between the two groups
From: Risk factors of necrotizing enterocolitis in twin preterm infants
NEC group | Control group | P value | |
|---|---|---|---|
Premature rupture of membranes | 16(23.9%) | 17(25.4%) | 0.841 |
Placental abnormality | 1(1.5%) | 1(1.5%) | - |
Neonatal respiratory distress syndrome | 21(31.4%) | 20(29.9%) | 0.851 |
Septicemia | 5(7.5%) | 6(9.0%) | 0.753 |
Congenital heart disease | |||
Hemodynamically significant patent ductus arteriosus | 5(7.5%) | 1(7.5%) | 0.033 |
Ventricular septal defect | 3(4.5%) | 0 | |
Small for gestational age | 17(25.4%) | 7(10.4%) | 0.024 |
Birth Apgar score | |||
1 min | 10 (8, 10) | 10 (9, 10) | 0.689 |
5 min | 10 (10, 10) | 10 (10, 10) | 0.902 |
10 min | 10 (10, 10) | 10 (10, 10) | 0.717 |
Mild asphyxia | 17(25.4%) | 7(10.4%) | 0.024 |
Severe asphyxia | 1(1.5%) | 1(1.5%) | - |
Using of pulmonary surfactant | 22(32.8%) | 20(29.9%) | 0.710 |
Using of vasoactive drugs | 32(47.8%) | 27(40.3%) | 0.384 |
Using of ibuprofen | 11(16.4%) | 15(22.4%) | 0.382 |
Using of caffeine | 22(32.8%) | 17(25.4%) | 0.342 |
Invasive ventilation | 12(17.9%) | 13(19.4%) | 0.825 |
Noninvasive ventilation | 48(71.6%) | 41(61.2%) | 0.456 |
Central vein catheterization | 35(52.2%) | 35(52.2%) | 1.000 |
Blood transfusion | 7(10.4%) | 9(13.4%) | 0.594 |
Gamma globulin infusion | 34(50.7%) | 35(52.2%) | 0.863 |
Albumin infusion | 33(49.3%) | 34(50.7%) | 0.863 |
Hemoglobin | 124.03 ± 34.08 | 131.44 ± 38.00 | 0.243 |
Antibiotics | 63(94.0%) | 60(89.6%) | 0.531 |
Situation of feeding | |||
Exclusive breastfeeding | 1(1.5%) | 3(4.5%) | 0.919 |
Human milk fortifier | 2(3.0%) | 3(4.5%) | |
Preterm milk feeding | 30(44.8%) | 28(41.8%) | |
Deeply hydrolyzed milk powder feeding | 14(20.9%) | 12(17.9%) | |
Mixed feeding | 18(26.9%) | 19(28.4%) | |
Fasting | 2(3.0%) | 2(3.0%) | |
Milk increase rate(ml/kg.d) | 6.48 ± 4.74 | 6.59 ± 5.63 | 0.901 |
Minimal feeding | 13(19.4%) | 8(11.9%) | 0.235 |