Table 3 Univariable and multivariable analysis for each predictor included in the model and simplified risk score to predict mortality among asphyxiated neonates admitted to NICU at FHCSH, Bahir Dar, Ethiopia, 2021
Predictor Variables | Univariable β (95% CI) | Full Model by Multivariable Analysis | Model Reduction by LR Test | SRS | ||
|---|---|---|---|---|---|---|
β (95% CI) | P–V | P–V | β (95% CI) | |||
Maternal age | ||||||
 20–35 | 0 | 0 | 0 | 0 | 0 | |
 < 20 | 0.08 (-0.38,0.54) | NA | - | - | - | |
 > 35 | 0.75 (.05,1.44) | 0.52 (-0.39,1.44) | 0.263 | 0.406 | NA | - |
Residence | ||||||
 Urban | 0 | 0 | 0 | 0 | 0 | |
 Rural | 0.67 (0.34,0.99) | 0.43 (.03,0.83) | 0.036 | 0.10 | 0.50 (0.12,0.88) | 1 |
ANC Visit | ||||||
 Yes | 0 | 0 | 0 | 0 | 0 | |
 No | 0.09 (-0.70,0.89) | NA | - | - | - | - |
Parity | ||||||
 Multipara | 0 | 0 | 0 | |||
 Primipara | 0.04 (-0.32,0.40) | NA | - | - | - | |
 G-Multipara | 0.74 (0.20,1.27) | 0.16 (-0.52,0.84) | 0.651 | 0.626 | NA | - |
BOH | ||||||
 No | 0 | 0 | 0 | 0 | 0 | |
 Yes | 0.52 (0.13,0.92) | 0.54 (0.04,1.05) | 0.035 | 0.160 | 0.60 (0.14,1.06) | 1 |
APH | ||||||
 No | 0 | 0 | 0 | 0 | 0 | |
 Yes | 0.09 (-0.50,0.67) | NA | - | - | - | - |
PROM | ||||||
 No | 0 | 0 | 0 | 0 | 0 | |
 Yes | 0 .11 (-0.31,0.54) | NA | - | - | - | - |
Labor Duration | ||||||
 ≤ 18 h | 0 | 0 | 0 | 0 | 0 | |
 > 18 h | 0.06 (-0.34,0.45) | NA | - | - | - | - |
Amniotic Fluid | ||||||
 Clear | 0 | 0 | 0 | 0 | 0 | |
 Stained | 0.59 (0.26,0.92) | 0.60 (0.20,1.01) | 0.003 | 0.035 | 0.62 (0.23,1.01) | 1 |
Pregnancy Type | ||||||
 Single | 0 | 0 | 0 | 0 | 0 | |
 Multiple | 1.11 (0.33,1.88) | 1.26 (0.33,2.20) | 0.008 | 0.109 | 1.31 (0.39,2.23) | 3 |
Place of Delivery | ||||||
 Inborn | 0 | 0 | 0 | 0 | 0 | |
 Referred | 0.03(-0.29,0.36) | NA | - | - | - | - |
Gestational Age | ||||||
 Term | 0 | 0 | 0 | 0 | 0 | |
 Preterm | 0.65 (0.20,1.10) | 0.32 (-0.29,0.92) | 0.302 | NA | - | |
 Posterm | 0.41 (-0.29,1.10) | 0.22 (-0.62,1.07) | 0.606 | 0.69 | NA | - |
Birth Weight | ||||||
 ≥ 2500(g) | 0 | 0 | 0 | 0 | 0 | |
 < 2500(g) | 0.66 (0.30,1.03) | 0.81 (0.31,1.31) | 0.001 | 0.008 | 0.95 (0.51,1.40) | 2 |
Sex of newborn | ||||||
 Female | 0 | 0 | 0 | 0 | 0 | |
 Male | 0 .37 (0.02, 0.73) | 0.26 (-0.15,0.67) | 0.21 | 0.59 | NA | - |
Age at admission | ||||||
 ≤ 6 h | 0 | 0 | 0 | 0 | 0 | |
 > 6 h | 0.10 (-0.24,0.44) | NA | - | - | - | - |
Stage of HIE | ||||||
 Stage I | 0 | 0 | 0 | |||
 Stage II | 0.77 (0.33,1.21) | 0.87 (0.39,1.34) | < 0.001 | < 0.001 | 0.80 (0.33,1.26) | 2 |
 Stage III | 2.54 (2.03,3.05) | 2.66 (2.09,3.22) | < 0.001 | 2.67 (2.12,3.23) | 5 | |
Heart Rate (bpm) | ||||||
 100–160 | 0 | 0 | 0 | |||
 < 100 | 0.69 (-0.11,1.48) | 0.48 (-0.50,1.47) | 0.34 | 0.70 | NA | - |
 ≥ 160 | 0.09 (-0.54,0.36) | NA | - | - | - | |
Temperature(oc) | ||||||
 35.5–37.5 | ||||||
 < 35.5 | 0.60 (0.27,0.94) | 0.34 (-0.07,0.74) | 0.105 | 0.55 | NA | - |
 > 37.5 | 0.13 (-0.94, 0.68) | NA | - | - | - | |
Sepsis | ||||||
 No | 0 | 0 | 0 | 0 | 0 | |
 Yes | 0.02 (-0.32,0.36) | NA | - | - | - | - |
Treatment Given | ||||||
 Yes | 0 | 0 | 0 | 0 | 0 | |
 No | -1.33 (-3.40,0.73) | -1.10 (-3.43,1.25) | 0.362 | 0.53 | NA | - |
Not cry at birth | ||||||
 No | 0 | 0 | 0 | |||
 Yes | 0.56 (.18,0.95) | 0.37 (-0.11,0.85) | 0.134 | 0.407 | NA | - |
Failure to suck | ||||||
 No | 0 | 0 | 0 | 0 | 0 | |
 Yes | 0.60 (0.22,0.96) | 0.58 (0.10,1.06) | 0.018 | 0.10 | 0.69 (0.26,1.11) | 1 |
Difficulty to Breath | ||||||
 No | 0 | 0 | 0 | 0 | 0 | |
 Yes | 0.39 (0.03,0.76) | 0.02 (-0.45,0.48) | 0.95 | 0.48 | NA | - |