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Table 2 Data related to the three deceased patients

From: Seizures in febrile children with SARS-CoV-2 infection: clinical features, short-term follow-up

Variable

Patient 1

Patient 2

Patient 3

Age

3 years and 9 months

2 years and 2 months

2 years and 2months

Sex

Female

Female

Female

Main symptoms

Fever, seizures, impaired consciousness

Fever, seizures, impaired consciousness

Fever, seizures, impaired consciousness, double inspiration

Seizure forms

GTCS

GTCS

GTCS

Underlying Diseases

None

None

None

State of consciousness

Coma

Coma

Coma

With or without shock

Shock

Shock

Shock

EEG

None

None

Background diffuse low voltage changes

Hematology tests

   

    WBC(*109/L)

5.7

3.89

9.72

    CRP(mg/L)

7.2

0.5

10.5

    PCT(ng/ml)

--

43.24

38.23

Treatment

   

    Ventilator

Invasive ventilator

Invasive ventilator

Invasive ventilator

    Drugs

Methylprednisolone

Gammaglobulin

Methylprednisolone

 

Gammaglobulin

Vasoactive drugs

Gammaglobulin

 

Vasoactive drugs

  

Head CT

None

Bilateral symmetric hypodense lesions in the thalami, accompanied by enlarged thalamic volume and similar low-density changes in the brainstem

The bilateral cerebellar hemispheres and thalamus exhibit symmetric patchy hypodense lesions. The density of the brainstem is reduced. In parts of the bilateral cerebral hemispheres, the grey-white matter differentiation is well-defined.

  1. GTCS: generalized tonic-clonic seizure;WBC: White blood cell count;CRP: C-reactive protein;CT:Computed Tomography;EEG:Electroencephalogram;PCT:Procalcitonin