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Table 4 The correlation of UCBMNCs characters with very preterm outcomes and peripheral blood differential count day one after birth

From: Umbilical cord blood cell characteristics in very preterm neonates for autologous cell therapy of preterm-associated complications

UCBMNCs characters

Cell concentration before processing*106/ml

CD34% in MNCs

Cell viability,%

Cord blood volume before processing, ml

CFU-GM number/105

MNCs

BPD

 P

0.25

0.274

0.721

0.98

0.359

 OR, 95% CI

1.056,0.963–1.158

0.389(0.072,2.112)

1.045(0.821,1.330)

1(0.979,1.002)

0.996(0.998,1.004)

NEC

 P

0.565

0.311

0.904

0.198

0.319

 OR, 95% CI

1.025,0.943–1.114

2.315(0.492,9.256)

0.986(0.786,1.003)

0.983(0.958,1.009)

1.003(0.997,1.010)

LOS

 P

0.203

0.561

0.051

0.784

0.238

 OR, 95% CI

0.788,0.546–1.137

1.27(0.567,2.843)

0.567(0.321,0.883)

1.005(0.967,1.046)

1.007(0.995,1.020)

IVH

 P

0.565

0.072

0.390

0.736

0.189

 OR, 95% CI

1.025,0.943,1.114

3.529(0.893,13,943)

0.918(0.756,1.116)

0.997(0.978,1.016)

1.004(0.998,1.010)

ROP

 P

0.411

0.231

0.424

0.124

0.060

 OR, 95% CI

0.952,0.847–1.070

2.501(0.559.11.191)

1.109(0.860,1.431)

1.016(0.996,1.037)

1.006(1.000,1.013)

RDS

 P

0.159

0.252

0.986

0.893

0.672

 OR, 95% CI

0.862,0.700–1.060

0.034(0.000,11.014)

0.992(0.404,2.433)

0.995(0.922,1.074)

1.010(0.963,1.061)

Anemia

 P

0.366

0.164

0.374

0.598

0.161

 OR, 95% CI

1.042,0.953–1.139

2.997(0.639,14.063)

0.914(0.749,1.115)

1.005(0.987,1.024)

1.005(0.998,1.011)

White blood cells (109/l)

 

 P, R

0.000,0.862

 OR, 95% CI

1.229,1.073–1.385

Neutrophile(109/l)

 P, R

0.000,0.834

 OR, 95% CI

0.992,0.851–1.134

Lymphocyte(109/l)

 P, R

0.000,0.369

 OR, 95% CI

0.119,0.055–0.184

PLT(109/l)

 P, R

0.010,0.273

 OR, 95% CI

3.294,0.791–5.776

HB(g/l)

 P, R

0.090,0.183

 OR, 95% CI

-0.803,-1.736–0.129

CRP(mg/l)

 P, R

0.113.0.171

 OR, 95% CI

0.096,-0.023–0.216

  1. UCBMNCs Umbilical cord blood mononuclear cells, IVH Intraventricular hemorrhage, NEC Necrotizing enterocolitis, ROP Retinopathy of prematurity, LOS Late onset sepsis, BPD Bronchopulmonary dysplasia, RDS Respiratory distress syndrome, PLT Platelet, HB Hemoglobin, CRP C-reactive protein, CI Confidence interval