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Table 2 Characteristics of the cord blood cells in very preterm infants

From: Umbilical cord blood cell characteristics in very preterm neonates for autologous cell therapy of preterm-associated complications

 

Total (n = 89)

GA < 30 weeks (n = 35)

GA ≥ 30weeks (n = 54)

P

Volume collected(ml),median, range

44(8,133)

44(20,129)

41(8,133)

0.311

Volume post processing(ml),median,range

25(16,44)

25(16,30)

25(17.44)

0.239

Total cells collected (108),median,range

2.76(0.22,13.20)

2.77(0.22,11.10)

2.75(0.25,13,20)

0.668

Total cells post processing (108),median,range

2.6(0.21,10.93)

2.6(0.21,9.48)

2.45(0.25,10.93)

0.665

Total cells ratio (after/before),median,range

0.91(0.63,1.00)

0.91(0.80,0.99)

0.91(0.63,1.00)

0.480

Cell concentration before processing*106/ml,median,range

6.13(0.65,32.57)

6.04(0.65,18.33)

6.23(0.82,32.57)

0.775

Cell concentration post processing*106/ml,median,range

9.24(1.03,42.02)

10.85(1.03,32.70)

.96(1.39,42.02)

0.486

Cell number (107)/kg post processing,median,range

15.79(1.52,90.29)

21.98(1.81,90.29)

13.77(1.52,88.75)

0.114

Cell number < 5 × 107/kg,n,%

7(7.9)

2(5.7)

5(9.3)

0.757

Cell number 5-9.99 × 107/kg,n,%

22(24.7)

8(22.9)

14(25.9)

Cell number ≥ 10 × 107/kg,n,%

60(67.4)

25(71.4)

35(64.8)

Volumes/kg required for infusing 1 × 107 cells/kg,median,range

1.08(0.24,9.71)

0.92(0.31,9.71)

1.12(0.24,7.19)

0.486

Infused volumes > 20ml/kg required for 1 × 107 cells/kg,n,%

0%

0%

0%

1.000

Volumes/kg required for infusing 5 × 107 cells/kg,median,range

5.42(1.19,48.54)

4.61(1.53,48.54)

5.58(1.19,35.97)

0.486

Infused volumes > 20ml/kg required for 5 × 107 cells/kg,n,%

3(3.4)

2(5.7)

1(1.9)

0.559

Volumes/kg required for infusing 10 × 107 cells/kg,median,range

10.82(2.38,97.09)

0.22(3.05,97.09)

11.16(2.38,71.94)

0.486

Infused volumes > 20ml/kg required for 10 × 107 cells/kg,n,%

23(25.8)

9(25.7)

14(25.9)

1.000

Cell viability after processing(%),median, range

96.73(90.37,98.79)

96.74(90.37,98.54)

96.51(90.47,98.79)

1.000

CD34 + cells proportion after processing(%),median, range

0.57(0.09,1.87)

0.66(0.15,1.50)

0.51(0.09,1.87)

0.225

CFU-GM number/105MNCs,median, range

7.33(0.21,241)

7.75(0.91,219)

6.8(0.21.241)

0.480

  1. GA Gestational age, MNCs Mononuclear cells, CFU-GM Colony forming unit -granulocyte and macrophage, CD34 Cluster differentiation 34