Skip to main content
Fig. 1 | BMC Pediatrics

Fig. 1

From: The first pineoblastoma case report of a patient with Sotos syndrome harboring NSD1 germline mutation

Fig. 1

MRI revealed a space-occupying lesion in the preoperative (A-C) and postoperative (D-F) pineal region. (A), Sagittal T1-weighted image showed that the tumor (arrows) was nearly isointense relative to gray matter. (B), Sagittal T2-weighted image showed that the tumor (arrows) was nearly isointense relative to gray matter. (C), Sagittal T1-weighted gadolinium-enhanced image showed homogeneous enhancement of the tumor (arrows). After surgery, the tumor disappeared on T1-weighted image (D), T2-weighted image (E), and T1-weighted gadolinium-enhanced image (F). HE staining from pineal regions suggested pineoblastoma (G) and NGS revealed comprehensive genomic profiling (H, I). Sanger sequencing of blood samples from the patient’s parents was carried out for family verification (J): Father (-), Mother (-)

Back to article page

BMC Pediatrics

ISSN: 1471-2431

Contact us