From: Effects of infant weight gain on subsequent allergic outcomes in the first 3 years of life
Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | |||
---|---|---|---|---|---|---|---|---|---|---|
Period of weight gain | Allergic outcomes | N (%) | N (%) | N (%) | N (%) | Reference group | Adjusted OR (95% CI) | Adjusted OR (95% Adjusted OR CI) (95% CI) | Adjusted OR (95% Adjusted | p-trend |
0 to 3 months | Wheeze with a positive skin prick test | 11 (6.7) | 15 (9.3) | 19 (11.8) | 19 (13.1) | 1.00 | 1.6 (0.6–4.5) | 1.8 (0.6–5.4) | 1.3 (0.4–4.0) | 0.7 |
Rhinitis with a positive skin prick test | 10 (6.7) | 9 (6.3) | 16 (10.6) | 24 (17.6) | 1.00 | 0.9 (0.3–3.1) | 1.3 (0.4–4.3) | 1.7 (0.5–6.0) | 0.3 | |
Atopic eczema with a positive skin prick test | 5 (3.4) | 10 (6.7) | 9 (6.6) | 10 (7.3) | 1.00 | 1.9 (0.5–7.1) | 1.4 (0.3–5.8) | 1.1 (0.3–4.9) | 0.9 | |
Positive skin prick test | 34 (17.4) | 36 (20.0) | 45 (24.7) | 59 (31.7) | 1.00 | 1.3 (0.7–2.6) | 1.6 (0.8–3.3) | 1.6 (0.8–3.3) | 0.2 | |
3 to 6 months | Wheeze with a positive skin prick test | 12 (7.6) | 14 (8.4) | 7 (4.5) | 16 (11.0) | 1.00 | 1.3 (0.4–3.9) | 0.3 (0.1–1.5) | 2.6 (0.9–7.3) | 0.2 |
Rhinitis with a positive skin prick test | 9 (6.3) | 22 (14.7) | 10 (7.0) | 13 (10.3) | 1.00 | 6.7 (1.4–31.8) | 3.2 (0.6–16.4) | 4.5 (0.9–22.2) | 0.3 | |
Atopic eczema with a positive skin prick test | 7 (4.9) | 6 (4.0) | 2 (1.4) | 7 (5.3) | 1.00 | 0.8 (0.2–3.1) | 0.2 (0.0–1.6) | 1.0 (0.3–3.8) | 0.8 | |
Positive skin prick test | 43 (23.8) | 41 (22.7) | 46 (25.8) | 35 (21.1) | 1.00 | 1.1 (0.6–2.2) | 1.1 (0.6–2.1) | 0.9 (0.5–1.8) | 0.8 | |
6 to 9 months | Wheeze with a positive skin prick test | 12 (7.6) | 11 (6.7) | 13 (8.5) | 8 (5.3) | 1.00 | 0.4 (0.1–1.4) | 0.7 (0.2–2.0) | 1.1 (0.3–3.5) | 0.9 |
Rhinitis with a positive skin prick test | 12 (8.3) | 13 (9.2) | 12 (8.6) | 9 (7.1) | 1.00 | 0.5 (0.1–1.8) | 0.6 (0.2–2.0) | 0.5 (0.1–1.9) | 0.3 | |
Atopic eczema with a positive skin prick test | 6 (4.2) | 7 (5.1) | 4 (3.0) | 2 (1.6) | 1.00 | 1.4 (0.4–5.8) | 0.8 (0.2–3.6) | 0.7 (0.1–4.3) | 0.6 | |
Positive skin prick test | 40 (23.3) | 45 (25.9) | 37 (22.2) | 34 (20.4) | 1.00 | 0.5 (0.3–0.96) | 0.5 (0.3–1.0) | 0.5 (0.3–1.0) | 0.06 | |
9 to 12 m o n th s | Wheeze with a positive skin prick test | 14 (8.9) | 7 (4.5) | 8 (4.9) | 9 (5.5) | 1.00 | 0.5 (0.1–1.6) | 0.7 (0.2–2.1) | 0.2 (0.0–0.8) | 0.04 |
Rhinitis with a positive skin prick test | 11 (8.2) | 8 (6.0) | 9 (6.1) | 17 (11.7) | 1.00 | 0.5 (0.1–2.3) | 0.7 (0.2–2.7) | 1.2 (0.3–4.2) | 0.7 | |
Atopic eczema with a positive skin prick test | 4 (2.9) | 1 (0.7) | 6 (4.6) | 4 (2.9) | 1.00 | # | 1.3 (0.3–5.7) | 0.5 (0.1–3.1) | 0.9 | |
Positive skin prick test | 43 (24.9) | 39 (23.8) | 37 (21.4) | 39 (22.9) | 1.00 | 0.9 (0.5–1.6) | 0.8 (0.4–1.5) | 0.5 (0.3–1.1) | 0.1 | |
12 to 15 months | Wheeze with a positive skin prick test | 6 (3.6) | 10 (6.0) | 8 (4.8) | 8 (4.6) | 1.00 | 1.7 (0.5–5.5) | 0.5 (0.1–2.1) | 1.1 (0.3–4.0) | 0.6 |
Rhinitis with a positive skin prick test | 8 (6.1) | 15 (10.7) | 11 (7.6) | 9 (6.0) | 1.00 | 1.3 (0.3–5.2) | 1.3 (0.3–5.1) | 0.8 (0.2–3.3) | 0.7 | |
Atopic eczema with a positive skin prick test | 4 (2.7) | 5 (3.3) | 2 (1.4) | 3 (1.9) | 1.00 | 1.3 (0.3–6.3) | # | 0.8 (0.1–5.4) | 0.3 | |
Positive skin prick test | 49 (27.8) | 40 (23.1) | 37 (20.9) | 37 (20.6) | 1.00 | 0.6 (0.3–1.0) | 0.4 (0.2–0.8) | 0.4 (0.2–0.8) | <0.01 |