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Table 5 Coverage achieved for hospital-acquired bloodstream infections with empiric antimicrobial regimens (2012–2013)*

From: Trends in paediatric bloodstream infections at a South African referral hospital

Antibiotic susceptibility

OVERALL n = 159

WARD n = 92

PICU n = 67

Ward vs PICU

SUSCEPTIBLE

Number (n)

Percentage (%)

Number (n)

Percentage (%)

Number (n)

Percentage (%)

p-value

piperacillin tazobactam + amikacin

122

76.7

71

77.2

50

74.6

0.7

ertapenem

110

69.1

71

77.2

40

59.7

0.02

meropenem

112

70.4

70

76

42

62.7

0.08

meropenem + amikacin

133

83.6

82

89.1

51

76

0.03

meropenem + vancomycin

119

74.8

73

79.3

46

68.7

0.14

  1. PICU = paediatric intensive care unit; *only pathogens isolated in 2012 and 2013 were included in this analysis in order to determine recent antimicrobial resistance patterns.