Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol

Table 9 Comparison of laboratory values at 20–24 weeks vs. 36 weeks gestation among HIV-uninfected women

Laboratory Parameter	Number of Pairs	Mean (*) of the paired differences	95% CI		p value*
			Lower	Upper
Red blood cells count 10⁶/μL	280	0.2	0.1	0.3	< 0.0001
Hemoglobin g/dl	280	0.2	0.1	0.4	0.01
Hematocrit %	280	0.7	0.1	1.3	0.01
Platelets 10³/μL	280	-17.6	-25.1	-10.0	< 0.0001
White blood cell count 10³/μL	279	-0.2	-0.4	0.1	0.2
Lymphocytes %	266	0.1	-1.1	1.2	0.9
Monocytes %	266	0.9	0.1	1.7	0.02
Granulocytes %	266	-0.9	-2.5	0.6	0.2
CD4+ T lymphocyte count cells/μL	134	-24.2	-71.9	23.6	0.3
CD8+ T lymphocyte count cells/μL	134	-12.5	-52.5	27.5	0.5
CD4+ T lymphocyte %	25	-2.5	-6.2	1.3	0.2
CD8+ T lymphocyte %	25	-1.2	-3.6	1.3	0.3
Total T lymphocytes as a % of all lymphocytes	19	1.1	-3.1	5.2	0.6

(*) For each pair, the 20–24 week laboratory value is subtracted from the 36 week value. Hence, a negative value indicates a decrease over time in the laboratory parameter.

ISSN: 1471-2431