Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol

Table 8 Comparison of laboratory values at 20–24 weeks vs. 36 weeks gestation among HIV-infected women

Laboratory Parameter	Number of Pairs	Mean (*) of the paired differences	95% CI		p value*
			Lower	Upper
Red blood cell count 10⁶/μL	1626		0.17	0.23	< 0.0001
Hemoglobin g/dl	1623	0.5	0.4	0.6	< 0.0001
Hematocrit %	1626	1.5	1.3	1.7	< 0.0001
Platelets 10³/μL	1625	-23.9	-27.5	-20.4	< 0.0001
White blood cell count 10³/μL	1623	-0.1	-0.2	0.1	0.3
Lymphocytes %	1570	0.5	0.0	1.0	0.1
Monocytes %	1570	0.5	0.2	0.9	0.002
Granulocytes %	1569	-0.8	-1.6	-0.1	0.02
CD4+ T lymphocyte count cells/μL	1343	14.8	7.1	22.5	0.0002
CD8+ T lymphocyte count cells/μL	1343	8.5	-6.6	23.5	0.3
CD4+ T lymphocyte %	107	-2.3	-3.7	-0.8	0.003
CD8+ T lymphocyte %	107	-2.5	-4.6	-0.4	0.02
Total T lymphocytes as a % of all lymphocytes	74	-1.3	-3.7	1.1	0.3

* For each pair, the 20–24 week laboratory value is subtracted from the 36 week value. Hence, a negative value indicates a decrease over time in the laboratory parameter.

ISSN: 1471-2431