Table 2 Characteristics of 7 girls with idiopathic CPP beginning before 3 years
From: Idiopathic central precocious puberty in girls: presentation factors
Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|---|---|---|---|---|---|---|
Age at onset, years | 0.5 | 0.7 | 1.0 | 1.0 | 1.7 | 2.0 | 2.0 |
Age at evaluation, years | 0.75 | 0.8 | 3.2 | 2.3 | 2.0 | 2.7 | 2.9 |
Height, SDS | 1.0 | 1.0 | 2.5 | 0.9 | 2.8 | 2.1 | 1.8 |
Growth rate, SDS | 3.3 | 0.1 | 2.4 | 1.8 | 0.4 | ||
BMI, SDS | -0.84 | 0.2 | 0.44 | -0.16 | -0.91 | 3.9 | 0.12 |
Bone age advance, years | 0.5 | 0.1 | 1.8 | 0.2 | 3.0 | 0.8 | 1.1 |
Uterus length, mm | 27 | NA | NA | 30 | NA | NA | NA |
Estradiol, pg/mL | 9 | 100 | 50 | 9 | 30 | 15 | 5 |
LH peak, IU/L | 3.1 | 52 | 34 | 2.6 | 17.4 | 23 | 3.6 |
FSH peak, IU/L | 28 | 27 | 23.3 | 17 | 11.4 | 21.4 | 22 |
LH/FSH peaks ratio | 0.11 | 2.0 | 1.4 | 0.15 | 1.5 | 1.1 | 0.16 |
GnRH analogue treatment | yes | yes | yes | yes | yes | yes | no |
Familial CPP | NA | NA | no | yes | NA | no | no |
Final height, SDS | NA | NA | 0.0 | NA | NA | -1.1 | NA |