Skip to main content

Table 5 Diagnostic work up in correctly (CR) and not correctly referred (NCR) children > 3 years old.

From: The diagnostic work up of growth failure in secondary health care; An evaluation of consensus guidelines

  

University hospital

General hospital

Difference in categories between 2 hospitals (p-value)

  

CR (n = 284) (%)

NCR (n = 63) (%)

CR (n = 85) (%)

NCR (n = 24) (%)

 

Routine laboratory investigations

      

Anemia/infections

 

0.4/39.8

0.0/25.4

1.2/57.6

4.2/37.5

< 0.01

Liver diseases

 

22.5/4.2

2.8/0.0

14.1/21.2

8.3/25.0

0.03

Renal diseases (blood)

 

1.4/27.3

0.0/17.5

0.0/38.8

0.0/33.3

0.5

Celiac disease

 

21.1/15.8

11.1/3.2

49.4/4.7

25.0/4.2

< 0.01

Hypothyroidism

 

37.0/3.2

2.5/0.0

45.9/3.5

29.2/8.3

0.02

Growth hormone deficiency

 

35.2

9.5

45.9

25

0.02

Turner syndrome *

 

17.2

6.5

14.0

18.1

1.0

Renal diseases (urine)

 

0.0/19.4

0.0/19.0

0.0/40.0

0.0/29.2

< 0.01

Combined categories (at least one test category)

 

4.9/52.1

1.6/39.7

18.8/49.4

33.3/16.7

< 0.01

Further and specific diagnostics

      

Special investigations

Chromosomal analyses for Turner syndrome*

26.2

6.5

26.0

0.0

0.9

 

Biopsy**

2.1

0.0

5.9

0.0

0.03

 

Zinc-determination

0.4

0.0

0.0

0.0

0.6

Further, more specific tests

GH-tests

16.2

3.2

12.9

0.0

0.3

 

Other tests***

8.8

3.2

28.2

25.0

< 0.01

  1. Percentages of patients with Complete (all elements)/partial (at least one element) evaluation are given (several test categories per patient).
  2. CR = Correctly referred; NCR = Not correctly referred
  3. * These categories are only applicable to girls. The percentages are therefore calculated only on the female population.
  4. **biopsy to rule out celiac disease.
  5. *** other tests, like stool examinations, X-rays of the skeleton, ultrasounds of abdomen, hart, kidneys and thyroids, serum levels of steroids, genetic analyses, immunologic tests and allergic tests