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Table 1 Differential diagnosis of childhood narrow angles

From: Acute myopia and angle closure glaucoma from topiramate in a seven-year-old: a case report and review of the literature

Anterior segment dysgenesis

Posterior ‘Pushing’ mechanism

 Corneal anomalies: microcornea, cornea plana/sclerocornea

Anterior rotation of ciliary body

 Axenfeld-Rieger syndrome, Peters anomaly, Aniridia

 Nanophthalmos, Inflammation (scleritis, uveitis, juvenile idiopathic arthritis)

 Ectopia lentis (trauma, homocystinuria, Marfan syndrome, Ehlers’-Danlos, syndrome, Weill-Marchesani syndrome

 Drug-induced

Pupillary block

Pressure from posterior segment

 Aphakia

 Tumor (retinoblastoma, medulloepithelioma)

 Microspherophakia

 Exudative retinal detachment

Anterior “Pulling’ mechanism without pupillary block

Contraction of retrolental tissue

 Neovascular (tuberous sclerosis)

 Persistent fetal vasculature

 Peripheral anterior synechiae

 Retinopathy of prematurity