Table 1 Baseline characteristics of the 14 participants with exercise induced bronchoconstriction
Subject | BMI (kg/m2) | Age | FEV1 (L) | FEV1% predicted | FVC (liter) | FEV1% predicted | Max fall FEV1 in ECT (%) | RDR mannitol (%/mg) | PD15 mannitol |
|---|---|---|---|---|---|---|---|---|---|
MCT positive | |||||||||
A | 39.7 | 3.24 | 83.5 | 3.98 | 84.5 | 15.7 | 0.059 | 293 | |
B | 25.0 | 2.34 | 128.6 | 2.86 | 134.9 | 29.1 | 0.034 | 569 | |
C | 16.4 | 2.02 | 125.3 | 2.56 | 133.3 | 61.7 | 0.120 | 133 | |
D | 17.2 | 3.09 | 109.2 | 3.97 | 116.8 | 48.7 | 0.155 | 102 | |
E | 36.4 | 2.43 | 92.4 | 2.82 | 89.5 | 16.0 | 0.037 | 512 | |
F | 29.7 | 3.54 | 101.4 | 4.89 | 115.9 | 29.7 | 0.313 | 49 | |
G | 25.8 | 4.45 | 100 | 5.82 | 107.6 | 22.5 | 0.039 | 475 | |
Mean ± SD or median (IQR) | 25.8 (19.1) | 14.1 ± 3.5 | 3.01 ± 0.83 | 105.8 ± 16.5 | 3.84 ± 1.20 | 111.8 ± 19.6 | 29.1 (32.7) | 0.059 (0.118) | 293 (410) |
MCT negative | |||||||||
H | 15.5 | 1.92 | 85.3 | 2.44 | 90.4 | 46.8 | 0.034 | ||
I | 35.0 | 4.52 | 113.6 | 5.02 | 103.9 | 20.8 | 0.030 | ||
J | 37.1 | 2.87 | 101.4 | 3.62 | 105.5 | 16.9 | 0.020 | ||
K | 30.0 | 3.41 | 104.9 | 4.85 | 130 | 42.9 | 0.075 | ||
L | 30.7 | 3.69 | 100.5 | 4.64 | 104.5 | 17.6 | 0.020 | ||
M | 35.2 | 5.78 | 136.3 | 7.23 | 140.4 | 18.3 | 0.030 | ||
N | 14.8 | 2.56 | 133.3 | 3.08 | 134.5 | 17.9 | 0 | ||
Mean ± SD or (Median) | 30.7 (19.7) | 14.1 ± 3 | 3.53 ± 1.29 | 110.8 ± 18.5 | 4.41 ± 1.57 | 115.6 ± 19 | 18.3 (25.3) | 0.030 (0.014) | |
p-value | 0.45 | ns | 0.22 | 0.24 | 0.31 | 0.45 | 0.29 | 0.03 |