Markers | Dehydrated n = 73 | Comparison n = 143 | AUC (SE) | P value |
---|---|---|---|---|
Dehydration score | 3 (0–8) | 0 (0–0) | <0.0001 | |
Pre-hydration systolic blood pressure z-score | 0.57 (-0.18-1.54) | 0.97 (0.02-1.90) | n.s. | |
Pre-hydration diastolic blood pressure z-score | 0.67 (-0.09-1.21) | 0.24 (-0.42, 1.10) | n.s. | |
Pre-hydration heart rate | 134 (112, 158) | 97 (84, 130) | <0.0001 | |
Urine Na/K ratio [17] | 0.69 (0–4.4) | 2.3(0–56) | 0.789(0.03) | <0.0001 |
Serum Osmolality [mOsm] [18] | 286 (231–684) | 289 (199–391) | 0.11 | |
Urine Na [mmol/L] [19] | 66.0 ± 55.6 | 144 ± 74 | 0.798(0.03) | <0.0001 |
FeNa [20] | 0.19 (0–0.89) | 0.52 (0–10.4) | 0.753(0.03) | <0.0001 |
FeUrea [21] | 0.398 (0.678-0.96) | 0.377 (0.055-4.504) | n.s. | |
Serum bicarbonate [mmol/L] | 20 (10–27) | 24 (18–30) | 0.821(0.03) | <0.0001 |
Blood urea [g/L] | 5.7 (1.2-41) | 5 (2.6-9.2) | 0.613(0.05) | 0.01 |
Serum creatinine [μmol/L] | 38 (16–408) | 45 (3.8-97) | 0.666(0.04) | 0 |
Schwartz eGFR [mL/min/1.73 m 2 ] | 131.6 ± 32.3 | 136.9 ± 23.2 | 0.18 | |
Cystatin C [mg/L] | 0.67 (0.43-2.89) | 0.66 (0.44-1.08) | n.s. | |
Cystatin C eGFR [mL/min/1.73 m 2 ] | 144.0 ± 36.9 | 147.6 ± 25.1 | n.s. | |
Urine osmolality [mOsm] | 805 ± 306 | 876 ± 402 | 0.2 | |
Urinary microalbumin/creatinine ratio [mg/mmol] [22] | 4.4 (0.4-61.1) | 2.3 (0.3-9.4) | 0.69 (0.04) | <0.0001 |
Urinary α1-microglobulin/creatinine ratio [mg/mmol] [22] | 1.75 (0.30-14.70) | 0.70 (0.20-11.30) | 0.809(0.04) | P < 0.001 |