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Table 3 Predicting performance of SNAP and other risk factors for development of BPD or death

From: Addition of SNAP to perinatal risk factors improves the prediction of bronchopulmonary dysplasia or death in critically ill preterm infants

 

AUC

95% CI

P value

Low gestational age

0.83

0.76-0.89

<0.001

SNAP

0.78

0.70-0.85

<0.001

Surfactant use

0.72

0.64-0.80

<0.001

Apnea of prematurity

0.59

0.50-0.69

0.050

Patent ductus arteriosus

0.57

0.47-0.66

0.174

SNAP, combined with gestational age

0.88

0.84-0.94

<0.001

SNAP, combined with surfactant use

0.81

0.75-0.88

<0.001

SNAP, combined with gestational age and surfactant use

0.90

0.85-0.95

<0.001

Combination of 5 risk factorsa

0.92

0.87-0.96

<0.001

P value (comparison of the difference between AUCs)

p = 0.352 (between SNAP and gestational age)

p = 0.178 (between SNAP combined with gestational age and gestational age alone)

p = 0.023 (between SNAP combined with gestational age and SNAP alone)

p = 0.026 (between combination of 5 risk factors and gestational age alone)

P = 0.002 (between combination of 5 risk factors and SNAP alone)

p = 0.362 (between combination of 5 risk factors and SNAP combined with gestational age)

  1. AUC area under the receiver-operating-characteristic curve, BPD bronchopulmonary dysplasia, CI confidence interval, SNAP the score for neonatal acute physiology.
  2. aFive risk factors: gestational age, SNAP, surfactant use, apnea of prematurity, and patent ductus arteriosus.