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Table 3 Baseline characteristics of the study participants

From: Infant flow biphasic nasal continuous positive airway pressure (BP- NCPAP) vs. infant flow NCPAP for the facilitation of extubation in infants' ≤ 1,250 grams: a randomized controlled trial

Variable*

BP-NCPAP

(N = 67)

NCPAP

(N = 69)

P value

Gestational age (weeks) [Mean (SD)]

27.3 ± 1.9

27.4 ± 1.7

0.60

Birth weight (grams) [Mean (SD)]

901 ± 200

896 ± 156

0.86

Male [N (%)]

39 (58%)

31 (44%)

0.13

Apgar score (1 minute) [Median (IQR)]

5 (3, 7)

5 (2, 7)

0.56

Apgar score (5 minutes) [Median (IQR)]

8 (7, 9)

8 (7, 9)

0.63

Mode of ventilation [N (%)]

   

IPPV

50 (75%)

51 (74%)

0.85

HFOV

14 (21%)

16 (23%)

 

HFJV

3 (4%)

2 (3%)

 

Age at first extubation (days) [Median (IQR)]

3 (1-67)

3 (1-62)

0.85

Time of blood gas prior to extubation (hours) [Median (IQR)]

9 (5, 14)

7 (5, 12)

0.15

Blood gas prior to extubation [Mean (SD)]

   

pH

7.3 ± 0.1

7.3 ± 0.1

0.12

PCO2

47.1 ± 11.0

48.5 ± 10.9

0.48

FiO2 [Mean (SD)]

0.24 ± 0.06

0.26 ± 0.08

0.40

Fulfilled preset extubation criteria [N (%)]

47 (70%)

55 (80%)

0.20

Accidental extubation in infants who did not meet preset extubation criteria [N (%)]

6 (9%)

7 (10%)

0.98

Surfactant administration [N (%)]

61 (91%)

66 (96%)

0.32

Caffeine administration [N (%)]

65 (97%)

64 (92%)

0.44

  1. *FiO2 = Fraction of inspired oxygen, HFJV = High frequency jet ventilation, HFOV = High frequency oscillatory ventilation, IPPV = Intermittent positive pressure ventilation, IQR = Inter-quartile range, N = Number, % = Percent, SD = Standard deviation