Table 5 Multivariable analysis of cancer treatment factors associated with BMD Z-score ≤ -1
From: Modifiable risk factors associated with bone deficits in childhood cancer survivors
Outcome: Lumbar spine BMD Z-score ≤ -1. | ||||
|---|---|---|---|---|
| Â | Category | OddsRatio | 95%CI | P |
Age at Study | ≤ 16 years | 1.0 | - | - |
| Â | > 16 years | 3.1 | 1.4-7.1 | 0.006 |
Ethnicity | Other | 1.0 | - | - |
| Â | White non-Hispanic | 2.2 | 0.9-6.7 | 0.135 |
Tanner stage, 1-5 | One stage increase | 0.7 | 0.5-0.9 | 0.015 |
Sex | Female | 1.0 | - | - |
| Â | Male | 1.1 | 0.6-1.9 | 0.732 |
Radiation Exposure | None | 1.0 | - | - |
| Â | Cranial Radiation | 2.5 | 1.0-5.7 | 0.040 |
| Â | Other Radiation | 2.4 | 1.0-5.5 | 0.041 |
Steroid Exposure | No | 1.0 | - | - |
| Â | Yes | 1.9 | 1.0-3.5 | 0.042 |