SCAMP: standardised, concentrated, additional macronutrients, parenteral nutrition in very preterm infants: a phase IV randomised, controlled exploratory study of macronutrient intake, growth and other aspects of neonatal care

Table 2 Daily flow chart summarising PN administration (maximum possible) and data collection

	PN administration (macronutrient content)								Week	Data collection (nutrition)
Age (d)	Protein (g)		Lipid (g)		Dextrose; PN (%)		Dextrose; Suppl (%)		1	Enteral/IV fluid intake (ICR)	U/EBG	Bone/LFT	TG	AA	Growth
	std	max	std	max	std	max	std	max	PN type
1	1.8	1.8	1.0	1.0	10	10	10	10	PN	•	•				•
2	1.8	1.8	1.0	1.0	10	10	10	10	Consent &	•	•	•
3	2.4	2.9	1.9	1.9	10	12	10	12	randomise	•	•				•
4	2.4	2.9	1.9	1.9	10	12	10	12		•	•	•
5	2.8	3.8	2.8	2.8	10	12	10	12		•	•
6	2.8	3.8	2.8	2.8	10	12	10	12	SCAMP	•	•	•
7	2.8	3.8	2.8	3.8	10	12	10	12	SCAMP	•	•		•	•
	PN administration (macronutrient content)								Week	Data collection (nutrition)
Age (d)	Protein (g)		Lipid (g)		Dextrose; PN (%)		Dextrose; Suppl (%)		2-4	Enteral/IV fluid intake (ICR)	U/EBG	Bone/LFT	TG	AA	Growth
	std	max	std	max	std	max	std	max	PN type
8	2.8	3.8	2.8	3.8	10	12	10	12	SCAMP	•	•				•
9	2.8	3.8	2.8	3.8	10	12	10	12	SCAMP	•	•	•
10	2.8	3.8	2.8	3.8	10	12	10	12	SCAMP	•	•
11	2.8	3.8	2.8	3.8	10	12	10	12	SCAMP	•	•	•
12	2.8	3.8	2.8	3.8	10	12	10	12	SCAMP	•	•
13	2.8	3.8	2.8	3.8	10	12	10	12	SCAMP	•	•	•
14	2.8	3.8	2.8	3.8	10	12	10	12	SCAMP	•	•		•	•

Legend: Daily flow chart summary of SCAMP nutrition study protocol including consent, randomisation, PN administration and data collection. Week 2 flow chart is repeated in week 3 and 4 to complete the 28 day intervention period. Day 29: Patient reverts to standard PN (if still on PN). All routine data collection stops apart from routine weekly growth data which continues until 36 weeks corrected for gestational age.
Abbreviations: stnd: standard PN (scNPN); max: scNPN_max; ICR: intensive care record of daily fluid/nutrient/drug administration; U/E, BG: routine biochemical monitoring of plasma electrolytes, glucose, lactate and blood gases; Bone/LFT: routine biochemical monitoring of plasma bone and liver biochemistry; TG: triglyceride levels; AA amino acid levels.

ISSN: 1471-2431