Table 1 Severe gastrointestinal cytomegalovirus infection in immuno-competent infants born at term
From: Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: Case Report
Reference | Age at onset | Breast feeding | Clinical findings | Diagnosis | Mode of transmission | Antiviral therapy |
|---|---|---|---|---|---|---|
Jonkhoff-Slok (8) | 5 weeks | Yes° | Bloody diarrhoea Rectal bleeding | Inclusion bodies at intestinal biopsy | Perinatal ? Cow's milk allergy ? | No |
Fox (7) | 5 weeks | Yes | Fever, Lymphoadenopathy Intractable diarrhoea Occult blood in stools | Inclusion bodies at duodenum biopsy | Congenital ? Perinatal ? | i.v. GCV for 5 weeks |
Quiros-Tejeira (9) | 2 months | Yes | Fever, watery diarrhoea | Severe colonic inflammatory changes, inclusion bodies | Perinatal ? | i.v. GCV for 2 weeks |
Rongkavilit (10) | 8 weeks | Yes | Profuse watery diarrhoea | Inclusion bodies in duodenum and sigmoid colon | Perinatal ? Postnatal (breast-feeding ?) | i.v. GCV for 4 weeks |
Buonuomo (1) | 8 weeks | Yes | Fever Anaemia Melena § | Positive PCR at duodenum biopsy | Perinatal ? | Oral VGCV for 5 weeks |