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Table 2 Clinical and demographic characteristics of preterm infants with or without BPD*P < 0.05

From: Nutritional support during the first week for infants with bronchopulmonary dysplasia and respiratory distress: a multicenter cohort study in China

 

BPD I group

345 (56.2)

BPD II group

174 (28.3)

BPD III group

89 (14.5)

Non-BPD group

672 (52.3)

Z/χ2

P value

GA, weeks, median (IQR)

29 (27,30)

28 (27,29)

28 (27,29.3)

29 (28.0,30.0)

87.324

< 0.001*

BW, grams, median (IQR)

1185 (950,1463)

1070 (908,1293)

1045 (888,1243)

1340 (1100,1530)

112.246

< 0.001*

Male sex, n (%)

205 (59.4)

96 (55.2)

54 (60.7)

383 (57.1)

1.302

0.729

Apgar score at 5 min, score,

n (%)

43.417

< 0.001*

<7

56 (16.2)

35 (20.1)

31 (34.8)

69 (10.3)

  

≥7

289 (83.8)

139 (79.9)

58 (65.2)

603 (89.7)

  

Maternal diabetes, N (%)

67 (19.4)

38 (21.8)

17 (19.1)

139 (20.7)

0.552

0.907

Maternal hypertension, N (%)

90 (26.1)

44 (25.3)

16 (18.0)

144 (21.4)

4.579

0.205

Assisted reproduction, N (%)

65 (19.0)

56 (32.2)

23 (25.8)

150 (22.4)

11.915

0.008*

PROM > 18 h,N (%)

87 (25.2)

35 (20.1)

17 (19.1)

183 (27.2)

5.621

0.132

IUGR, N (%)

25 (7.2)

15 (8.6)

11 (12.4)

47 (7.0)

3.512

0.319

Respiratory distress score at admission, score

    

59.890

< 0.001*

5–8, N (%)

311 (90.1)

150 (86.2)

72 (80.9)

658 (97.8)

  

> 8, N (%)

34 (9.9)

24 (13.8)

17 (19.1)

15 (2.2)

  

Surfactant, N (%)

272 (78.8)

160 (92)

83 (93.3)

414 (61.6)

99.386

< 0.001*

Mechanical ventilation, N (%)

201 (58.3)

139 (79.9)

76 (85.4)

281 (41.8)

125.018

< 0.001*

Ventilator days, ds, median (IQR)

6.0 (3.0,13.4)

9.6 (4.0,22.0)

21.3 (8.0,38.1)

3.0 (1.2,7.3)

241.258

< 0.001*

hsPDA, N (%)

106 (30.7)

59 (33.9)

38 (42.7)

115 (17.1)

50.748

< 0.001*

NEC(Stage ≥ 2), N (%)

38 (11.0)

33 (19.0)

20 (22.5)

41 (6.1)

41.383

< 0.001*

LOS, ds, median (IQR)

56 (44,73)

68 (54,86)

78 (60,106)

46 (35,59)

295.460

< 0.001*

  1. BPD, bronchopulmonary dysplasia; GA, gestational age; BW, birth weight; PPROM, preterm premature rupture of membranes; IUGR, intrauterine growth retardation; hsPDA, hemodynamically significant patent ductus arteriosus; NEC, necrotizing enterocolitis; LOS, length of stay; IQR, interquartile range; SD, standard deviation