Table 1 Demographic and laboratory characteristics of the study groups before the study
From: Erythroferrone and hepcidin levels in children with iron deficiency anemia
Group 3 (n = 26) | Group 1 (n = 26) | P value | |
|---|---|---|---|
Age | 9.46 ± 3.93 | 7.62 ± 3.77 | 0.090 |
Gender | |||
Boy | 9 (34.7%) | 11 (42.3%) | 0.430 |
Girl | 17 (65.3%) | 15 (57.7%) | |
Leukocyte count (mm3) | 7.53 ± 1.76 | 8.21 ± 2.15 | 0.292 |
Hemoglobin(g/dL) | 13.87 ± 0.95 | 12.45 ± 0.78 | < 0.001 |
Hematocrit (%) | 39.5 ± 2.68 | 38.63 ± 3.25 | 0.304 |
MCV (fl.) | 79.68 ± 3.91 | 75.36 ± 4.8 | 0.001 |
MCH (pg) | 28.03 ± 1.78 | 25.45 ± 1.96 | < 0.001 |
MCHC (g/dl) | 35.18 ± 1.19 | 33.75 ± 1.37 | < 0.001 |
Platelet count (mm3) | 313.6 ± 72.3 | 335.9 ± 67.7 | 0.260 |
RDW | 12.43 ± 0.72 | 13.38 ± 1.06 | 0.001 |
Neutrophil % | 45.63 ± 11.79 | 42.58 ± 16.67 | 0.458 |
Leukocyte % | 43.02 ± 11.39 | 43.88 ± 17.93 | 0.955 |
Monocyte % | 7.63 ± 1.67 | 7.26 ± 2.27 | 0.521 |
Eosinophil % | 2.47 ± 2.7 | 2.06 ± 2.81 | 0.599 |
Iron (µg/mL) | 105.62 ± 33.44 | 43.38 ± 12.16 | < 0.001 |
Iron binding capacity (µg/mL) | 395 ± 44.78 | 416.77 ± 56.69 | 0.135 |
Ferritin(ng/mL) | 30.62 ± 12.92 | 15.16 ± 9.13 | < 0.001 |
Hepcidin (pg/mL) | 4358.3 ± 840.3 | 2600.9 ± 1588.1 | < 0.001 |
Erythroferrone (ng/mL) | 0.137 ± 0.003 | 0.143 ± 0.020 | 0.133 |