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  1. The increased survival of preterm and very low birth weight infants in recent years has been well documented but continued surveillance is required in order to monitor the effects of new therapeutic interventi...

    Authors: Huw P Jones, Stella Karuri, Catherine MG Cronin, Arne Ohlsson, Abraham Peliowski, Anne Synnes and Shoo K Lee

    Citation: BMC Pediatrics 2005 5:40

    Content type: Research article

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  2. Bronchitis obliterans is a severe and extremely rare complication of respiratory tract infections in children and is characterized by massive atelectasis and collapse of the affected lung. Of the rare cases re...

    Authors: Elke Govaere, Dirk Van Raemdonck, Hugo Devlieger, Maria-Helena Smet, Eric Verbeken, Marijke Proesmans and Kris De Boeck

    Citation: BMC Pediatrics 2005 5:39

    Content type: Case report

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  3. The delivery of optimal medical care to children is dependent on the availability of child relevant research. Our objectives were to: i) systematically review and describe how children are handled in reviews o...

    Authors: Kristie Cramer, Natasha Wiebe, Virginia Moyer, Lisa Hartling, Katrina Williams, George Swingler and Terry P Klassen

    Citation: BMC Pediatrics 2005 5:38

    Content type: Research article

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  4. The antipyretic effectiveness of rectal versus oral acetaminophen is not well established. This study is designed to compare the antipyretic effectiveness of two rectal acetaminophen doses (15 mg/kg) and (35 m...

    Authors: Mona Nabulsi, Hala Tamim, Ramzi Sabra, Ziyad Mahfoud, Shadi Malaeb, Hadi Fakih and Mohammad Mikati

    Citation: BMC Pediatrics 2005 5:35

    Content type: Research article

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  5. Tourette Syndrome (TS) is a neurodevelopmental disorder of childhood. Learning disabilities are frequently comorbid with TS. Using the largest sample of TS patients ever reported, we sought to identify differe...

    Authors: Larry Burd, Roger D Freeman, Marilyn G Klug and Jacob Kerbeshian

    Citation: BMC Pediatrics 2005 5:34

    Content type: Research article

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  6. Because there are no child-friendly, validated, self-report measures of dyspnea or breathlessness, we developed, and provided initial validation, of three, 7-item, pictorial scales depicting three sub-construc...

    Authors: Patrick J McGrath, Paul T Pianosi, Anita M Unruh and Chloe P Buckley

    Citation: BMC Pediatrics 2005 5:33

    Content type: Research article

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  7. Spina Bifida (SB) is the second most common birth defect worldwide. Since the chances of survival in children with severe SB-forms have increased, medical care has shifted its emphasis from life-saving interve...

    Authors: Ignace PR Vermaes, Jan MAM Janssens, Anna MT Bosman and Jan RM Gerris

    Citation: BMC Pediatrics 2005 5:32

    Content type: Research article

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  8. Acute viral bronchiolitis is one of the most common causes of hospitalisation during infancy in our region with respiratory syncytial virus (RSV) historically being the major causative agent. Many infants with...

    Authors: Hans-Olav Fjærli, Teresa Farstad, Gisle Rød, Gunn Kristin Ufert, Pål Gulbrandsen and Britt Nakstad

    Citation: BMC Pediatrics 2005 5:31

    Content type: Research article

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  9. PCO2 and PO2 are important monitoring parameters in neonatal intensive care units (NICU). Compared to conventional blood gas measurements that cause significant blood loss in preterms, transcutaneous (tc) measure...

    Authors: Mario Rüdiger, Kerstin Töpfer, Hannes Hammer, Gerd Schmalisch and Roland R Wauer

    Citation: BMC Pediatrics 2005 5:30

    Content type: Research article

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  10. Iron supplementation may be associated with oxidative stress particularly in premature infants. Our purpose was to examine 1) early supplemental iron during treatment with erythropoietin (EPO) and oxidative st...

    Authors: James K Friel, Khalid Aziz, Wayne L Andrews and Robert E Serfass

    Citation: BMC Pediatrics 2005 5:29

    Content type: Research article

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  11. Little is known about the factors that predispose to the occurrence and severity of cardio-respiratory symptoms during the placement of a prematurely born infant in a car seat. The impact of gestational age, w...

    Authors: Vallier C Ojadi, Anna Petrova, Rajeev Mehta and Thomas Hegyi

    Citation: BMC Pediatrics 2005 5:28

    Content type: Research article

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  12. Middle ear disease (otitis media) is common and frequently severe in Australian Aboriginal children. There have not been any recent large-scale surveys using clear definitions and a standardised middle ear ass...

    Authors: Peter S Morris, Amanda J Leach, Peter Silberberg, Gabrielle Mellon, Cate Wilson, Elizabeth Hamilton and Jemima Beissbarth

    Citation: BMC Pediatrics 2005 5:27

    Content type: Research article

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  13. Improved survival due to advances in neonatal care has brought issues such as postnatal growth and development more to the focus of our attention. Most studies report stunting in children born very preterm and...

    Authors: Noël BB Knops, Kommer CA Sneeuw, Ronald Brand, Elysee TM Hille, A Lya den Ouden, Jan-Maarten Wit and S Pauline Verloove-Vanhorick

    Citation: BMC Pediatrics 2005 5:26

    Content type: Research article

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  14. In children with severe generalized cerebral palsy, pneumonias are a major health issue. Malnutrition, dysphagia, gastro-oesophageal reflux, impaired respiratory function and constipation are hypothesized risk...

    Authors: Rebekka Veugelers, Elsbeth AC Calis, Corine Penning, Arianne Verhagen, Roos Bernsen, Jan Bouquet, Marc A Benninga, Peter JFM Merkus, Hubertus GM Arets, Dick Tibboel and Heleen M Evenhuis

    Citation: BMC Pediatrics 2005 5:25

    Content type: Study protocol

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  15. Gastroesophageal reflux disease (GERD) is believed to be more common in adult males as compared to females. It also has been shown in adults to be more common in Caucasians. We wanted to determine ethnicity an...

    Authors: Dena Nazer, Ronald Thomas and Vasundhara Tolia

    Citation: BMC Pediatrics 2005 5:24

    Content type: Research article

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  16. Information is lacking on the effects of congenital toxoplasmosis on development, behavior, and impairment in later childhood, as well as on parental concerns and anxiety. This information is important for cou...

    Authors: Katherine Freeman, Alison Salt, Andrea Prusa, Gunilla Malm, Nicole Ferret, Wilma Buffolano, Dorthe Schmidt, Hooi Kuan Tan and Ruth E Gilbert

    Citation: BMC Pediatrics 2005 5:23

    Content type: Research article

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  17. Nosocomial infection (NI), particularly with positive blood or cerebrospinal fluid bacterial cultures, is a major cause of morbidity in neonatal intensive care units (NICUs). Rates of NI appear to vary substan...

    Authors: Khalid Aziz, Douglas D McMillan, Wayne Andrews, Margaret Pendray, Zhenguo Qiu, Stella Karuri and Shoo K Lee

    Citation: BMC Pediatrics 2005 5:22

    Content type: Research article

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  18. We aimed to determine how response to a parent-completed postal questionnaire measuring development, behaviour, impairment, and parental concerns and anxiety, varies in different European centres.

    Authors: A Salt, K Freeman, A Prusa, N Ferret, W Buffolano, G Malm, D Schmidt, HK Tan and RE Gilbert

    Citation: BMC Pediatrics 2005 5:21

    Content type: Research article

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  19. Induced mutagenesis in utero is likely to have life-long repercussions for the exposed fetus, affecting survival, birth weight and susceptibility to both childhood and adult-onset diseases, such as cancer. In the...

    Authors: Stephen G Grant

    Citation: BMC Pediatrics 2005 5:20

    Content type: Research article

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  20. Determination of PC20-FEV1 during Methacholine bronchial provocation test (MCT) is considered to be impossible in preschool children, as it requires repetitive spirometry sets. The aim of this study was to assess...

    Authors: Lea Bentur, Raphael Beck, Nael Elias, Asher Barak, Ori Efrati, Yaacov Yahav and Daphna Vilozni

    Citation: BMC Pediatrics 2005 5:19

    Content type: Research article

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  21. For treatment of Graf class IIb dysplastic hips at walking onset a treatment concept with abduction splints allowing patterns as walking and crawling under constant abduction control was investigated. However,...

    Authors: Henning Windhagen, Fritz Thorey, Heinrich Kronewid, Thomas Pressel, Dieter Herold and Christina Stukenborg-Colsman

    Citation: BMC Pediatrics 2005 5:17

    Content type: Research article

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  22. It is unclear why some children with acute otitis media (AOM) have poor outcomes. Our aim was to describe the clinical course of AOM and the associated bacterial nasopharyngeal colonisation in a high-risk popu...

    Authors: Katherine B Gibney, Peter S Morris, Jonathan R Carapetis, Susan A Skull, Heidi C Smith-Vaughan, Elizabeth Stubbs and Amanda J Leach

    Citation: BMC Pediatrics 2005 5:16

    Content type: Research article

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  23. Growth-enhancing hormone treatment is considered a possible intervention in short but otherwise healthy adolescents. Although height gain is an obvious measure for evaluating hormone treatment, this may not be...

    Authors: Hanneke Visser – van Balen, Rinie Geenen, Gerdine A Kamp, Jaap Huisman, Jan M Wit and Gerben Sinnema

    Citation: BMC Pediatrics 2005 5:15

    Content type: Research article

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  24. Kawasaki disease is a systemic vasculitis and may affect cerebral function acutely. The aim of the present study was to measure a number of behaviour and social parameters within a cohort of Kawasaki disease p...

    Authors: Daniel Carlton-Conway, Raju Ahluwalia, Lucy Henry, Colin Michie, Louise Wood and Robert Tulloh

    Citation: BMC Pediatrics 2005 5:14

    Content type: Research article

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  25. The appropriateness of an individual's intra uterine growth is now considered an important determinant of both short and long term outcomes, yet currently used measures have several shortcomings. This study de...

    Authors: Eve M Blair, Yingxin Liu, Nicholas H de Klerk and David M Lawrence

    Citation: BMC Pediatrics 2005 5:13

    Content type: Research article

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  26. There are no standard criteria for when to discontinue intravenous antimicrobial therapy (IVAMT) in children with febrile neutropenia (FN), but it is now common to discontinue IVAMT and discharge patients with...

    Authors: Heather Hodgson-Viden, Paul E Grundy and Joan L Robinson

    Citation: BMC Pediatrics 2005 5:10

    Content type: Research article

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  27. Mucopolysaccharidoses are heritable, metabolic diseases caused by deficiency in an activity of one of specific lysosomal enzymes involved in degradation of mucoplysaccharides (glycosaminoglycans). Among many m...

    Authors: Grzegorz Węgrzyn, Julianna Kurlenda, Anna Liberek, Anna Tylki-Szymańska, Barbara Czartoryska, Ewa Piotrowska, Joanna Jakóbkiewicz-Banecka and Alicja Węgrzyn

    Citation: BMC Pediatrics 2005 5:9

    Content type: Case report

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  28. Advances in medical technology may be increasing the population of children who are technology-dependent (TD). We assessed the proportion of children discharged from a children's hospital who are judged to be ...

    Authors: Chris Feudtner, Nanci Larter Villareale, Barbara Morray, Virginia Sharp, Ross M Hays and John M Neff

    Citation: BMC Pediatrics 2005 5:8

    Content type: Research article

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  29. Bronchiolitis is the most common cause of lower respiratory tract illness in infancy, and hospital admission rates appear to be increasing in Canada and the United States. Inhaled beta agonists offer only mode...

    Authors: Joanne M Langley, Michael B Smith, John C LeBlanc, Heather Joudrey, Cecil R Ojah and Paul Pianosi

    Citation: BMC Pediatrics 2005 5:7

    Content type: Research article

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  30. Phenylketonuria is an inborn error of amino acid metabolism which can cause severe damage to the patient or, in the case of maternal phenylketonuria, to the foetus. The maternal phenylketonuria syndrome is cau...

    Authors: Ina Knerr, Johannes Zschocke, Stefan Schellmoser, Hans G Topf, Corina Weigel, Jörg Dötsch and Wolfgang Rascher

    Citation: BMC Pediatrics 2005 5:5

    Content type: Case report

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  31. Urinary tract infection (UTI) is one of the most common sources of infection in children under five. Prompt diagnosis and treatment is important to reduce the risk of renal scarring. Rapid, cost-effective, met...

    Authors: Penny Whiting, Marie Westwood, Ian Watt, Julie Cooper and Jos Kleijnen

    Citation: BMC Pediatrics 2005 5:4

    Content type: Research article

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  32. Cyclical Vomiting Syndrome (CVS) is characterised by discrete, unexplained episodes of intense nausea and vomiting, and mainly affects children and adolescents. Comprehending Cyclical Vomiting Syndrome require...

    Authors: Fiona E McRonald and David R Fleisher

    Citation: BMC Pediatrics 2005 5:3

    Content type: Case report

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  33. The management of burn injuries is reported as painful, distressing and a cause of anxiety in children and their parents. Child's and parents' pain and anxiety, often contributes to extended time required for ...

    Authors: Debashish A Das, Karen A Grimmer, Anthony L Sparnon, Sarah E McRae and Bruce H Thomas

    Citation: BMC Pediatrics 2005 5:1

    Content type: Research article

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  34. The ACE gene contains a polymorphism consisting of either the presence (insertion, I) or absence (deletion, D) of a 287 bp alu repeat in intron 16. The D allele is associated with increased ACE activity in bot...

    Authors: Krishna Yanamandra, John Loggins and R John Baier

    Citation: BMC Pediatrics 2004 4:26

    Content type: Research article

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  35. RSV is recognized as the most important cause of serious lower respiratory tract illness in infants and young children worldwide leading to hospitalisation in a great number of cases, especially in certain hig...

    Authors: Hans-Olav Fjaerli, Teresa Farstad and Dag Bratlid

    Citation: BMC Pediatrics 2004 4:25

    Content type: Research article

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  36. There is little information in the research literature on how parents of children who spend time in a neonatal intensive care unit (NICU) adapt psychologically to the demands of caregiving beyond the initial h...

    Authors: Anne F Klassen, Shoo K Lee, Parminder Raina and Sarka Lisonkova

    Citation: BMC Pediatrics 2004 4:24

    Content type: Research article

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  37. To determine whether healthcare professionals perceive the pain of infants differently due to their understanding of that infant's level of risk for neurological impairment.

    Authors: Lynn M Breau, Patrick J McGrath, Bonnie Stevens, Joseph Beyene, Carol S Camfield, G Allen Finley, Linda Franck, Alexandra Howlett, Karel O'Brien and Arne Ohlsson

    Citation: BMC Pediatrics 2004 4:23

    Content type: Research article

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  38. Several studies have linked low birth weight to adverse levels of cardiovascular risk factors and related diseases. However, information is sparse at a community level in the U.S. general population regarding ...

    Authors: Maria G Frontini, Sathanur R Srinivasan, Jihua Xu and Gerald S Berenson

    Citation: BMC Pediatrics 2004 4:22

    Content type: Research article

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  39. We sought to elicit preference weights from parents for health states corresponding to children with various levels of severity of atopic dermatitis. We also evaluated the hypothesis that parents with children...

    Authors: Joëlle Y Friedman, Shelby D Reed, Kevin P Weinfurt, Kristijan H Kahler, Emmanuel B Walter and Kevin A Schulman

    Citation: BMC Pediatrics 2004 4:21

    Content type: Research article

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  40. Elective endotracheal intubations are still commonly performed without premedication in many institutions. The hypothesis tested in this study was that morphine given prior to elective intubations in neonates ...

    Authors: Brigitte Lemyre, Joanne Doucette, Angela Kalyn, Shari Gray and Michael L Marrin

    Citation: BMC Pediatrics 2004 4:20

    Content type: Research article

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  41. Lung disease in patients with cystic fibrosis is thought to develop as a result of airway inflammation, infection, and obstruction. Pulmonary therapies for cystic fibrosis that reduce airway inflammation inclu...

    Authors: Jennifer E Mackey and Ran D Anbar

    Citation: BMC Pediatrics 2004 4:19

    Content type: Case report

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  42. Adjuvant therapy to ORT with probiotic bacteria for infants with acute watery diarrhea has been under active investigation. Most studies have been done in the developed world showing benefit only for viral mil...

    Authors: Eduardo Salazar-Lindo, Percy Miranda-Langschwager, Miguel Campos-Sanchez, Elsa Chea-Woo and R Bradley Sack

    Citation: BMC Pediatrics 2004 4:18

    Content type: Research article

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