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  1. Even minor abnormalities of early child development may have dramatic long term consequences. Accurate prevalence rates for a range of developmental impairments have been difficult to establish. Since related ...

    Authors: Heribert L Stich, Bernhard Th Baune, Riccardo N Caniato, Rafael T Mikolajczyk and Alexander Krämer
    Citation: BMC Pediatrics 2012 12:188
  2. The use of biomarkers has expanded considerably, as an alternative to questionnaire-based metrics of environmental tobacco smoke (ETS); few studies have assessed the affect of such alternative metrics on diver...

    Authors: Chris Carlsten, Helen Dimich-Ward, Anne DyBuncio, Allan B Becker and Moira Chan-Yeung
    Citation: BMC Pediatrics 2012 12:187
  3. The burden of disability is more severe among children in low income countries. Moreover, the number of children with disabilities (CWDs) in sub-Saharan Africa is predicted to increase with reduction in child ...

    Authors: Yoshito Kawakatsu, Satoshi Kaneko, Mohamed Karama and Sumihisa Honda
    Citation: BMC Pediatrics 2012 12:186
  4. The incidence of acute otitis media (AOM) vary from country to country. Geographical variations together with differences in study designs, reporting and settings play a role. We assessed the incidence of AOM ...

    Authors: Paola Marchisio, Luigi Cantarutti, Miriam Sturkenboom, Silvia Girotto, Gino Picelli, Daniele Dona, Antonio Scamarcia, Marco Villa and Carlo Giaquinto
    Citation: BMC Pediatrics 2012 12:185
  5. Oral clefts are one of the most common birth defects with significant medical, psychosocial, and economic ramifications. Oral clefts have a complex etiology with genetic and environmental risk factors. There a...

    Authors: George L Wehby, Norman Goco, Danilo Moretti-Ferreira, Temis Felix, Antonio Richieri-Costa, Carla Padovani, Fernanda Queiros, Camilla Vila Nova Guimaraes, Rui Pereira, Steve Litavecz, Tyler Hartwell, Hrishikesh Chakraborty, Lorette Javois and Jeffrey C Murray
    Citation: BMC Pediatrics 2012 12:184
  6. Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reach...

    Authors: Steve Innes, Mark F Cotton, Richard Haubrich, Maria M Conradie, Margaret van Niekerk, Clair Edson, Helena Rabie, Sonia Jain, Xiaoying Sun, Ekkehard W Zöllner, Stephen Hough and Sara H Browne
    Citation: BMC Pediatrics 2012 12:183
  7. Eustachian tube (ET) dysfunction plays an important role in the pathogenesis of acute otitis media (AOM). Unfortunately, there is a lack of knowledge about the exact role of the ET’s bony support, the temporal...

    Authors: Chantal Morin, Dominique Dorion, Jean-Marie Moutquin and Mélanie Levasseur
    Citation: BMC Pediatrics 2012 12:181
  8. Establishing healthy physical activity (PA) behaviours in early childhood is important for future PA behaviours. Parents play a central role in young children’s PA. However, there is currently little research ...

    Authors: Georgina F Bentley, Joanna K Goodred, Russell Jago, Simon J Sebire, Patricia J Lucas, Kenneth R Fox, Sarah Stewart-Brown and Katrina M Turner
    Citation: BMC Pediatrics 2012 12:180
  9. Studies on the association of birth by caesarean section (C/S) and allergies have produced conflicting findings. Furthermore, evidence on whether this association may differ in those at risk of atopy is limite...

    Authors: Ourania Kolokotroni, Nicos Middleton, Marina Gavatha, Demetris Lamnisos, Kostas N Priftis and Panayiotis K Yiallouros
    Citation: BMC Pediatrics 2012 12:179
  10. PEG-based laxatives are considered today the gold standard for the treatment of constipation in children. PEG formulations differ in terms of composition of inactive ingredients which may have an impact on acc...

    Authors: Francesco Savino, Serena Viola, Maiullari Erasmo, Giovanni Di Nardo, Salvatore Oliva and Salvatore Cucchiara
    Citation: BMC Pediatrics 2012 12:178
  11. Pediatric rehabilitation considers Family-centered service (FCS) as a way to increase participation of children with a physical disability in daily life. An important principal is that parents greatly contribu...

    Authors: Barbara Piškur, Anna JHM Beurskens, Marian J Jongmans, Marjolijn Ketelaar, Meghan Norton, Christina A Frings, Helena Hemmingsson and Rob JEM Smeets
    Citation: BMC Pediatrics 2012 12:177
  12. The ability of different obesity indices to predict cardiovascular risk is still debated in youth and few data are available in sub Saharan Africa. We compared the associations between several indices of obesi...

    Authors: Pascal Bovet, Tiphaine Arlabosse, Bharathi Viswanathan and Gary Myers
    Citation: BMC Pediatrics 2012 12:176
  13. Allergy represents a risk factor at the base of sleep-disordered breathing in pediatric age. Among allergic diseases, the atopy is characterized by a tendency to be “hyperallergic.” Sleep-disordered breathing ...

    Authors: Anna Maria Zicari, Giuseppe Marzo, Anna Rugiano, Camilla Celani, Maria Palma Carbone, Simona Tecco and Marzia Duse
    Citation: BMC Pediatrics 2012 12:175
  14. Evaluation of elementary writing skills in children is usually obtained with high resolution (and high cost) techniques or with low resolution pen-and-paper tests. In this observational study we tested a quant...

    Authors: Matteo Chiappedi, Rosella Togni, Elisabetta De Bernardi, Ilaria Maria Carlotta Baschenis, Sara Battezzato, Umberto Balottin, Elena Dalla Toffola and Maurizio Bejor
    Citation: BMC Pediatrics 2012 12:173
  15. Evaluation of palpable neck masses may be a diagnostic problem in pediatric patients, with differential diagnosis including congenital, inflammatory, tumoral and traumatic lesions. Ultrasonography is usually a...

    Authors: Vincenzo Davide Catania, Carlo Manzoni, Mariangela Novello, Libero Lauriola and Antonella Coli
    Citation: BMC Pediatrics 2012 12:172
  16. The objective of this work was to explore the impact on parents of the bronchiolitis hospitalization of their infant using the Impact of Bronchiolitis Hospitalization Questionnaire (IBHQ©).

    Authors: Alexandre Lapillonne, Antoine Regnault, Véronique Gournay, Jean-Bernard Gouyon, Hélène Gilet, Daniela Anghelescu, Tatiana Miloradovich, Benoit Arnould and Guy Moriette
    Citation: BMC Pediatrics 2012 12:171
  17. We assessed anthropometric status, breastfeeding duration, morbidity, and mortality outcomes during the first four years of life according to gestational age, in three population-based birth cohorts in the cit...

    Authors: Fernando C Barros, José Luis Diaz Rossello, Alicia Matijasevich, Samuel C Dumith, Aluisio J D Barros, Iná Silva dos Santos, Denise Mota and Cesar G Victora
    Citation: BMC Pediatrics 2012 12:169
  18. Severe eczema in young children is associated with an increased risk of developing asthma and rhino-conjunctivitis. In the general population, however, most cases of eczema are mild to moderate. In an unselect...

    Authors: Marit Saunes, Torbjørn Øien, Christian K Dotterud, Pål R Romundstad, Ola Storrø, Turid L Holmen and Roar Johnsen
    Citation: BMC Pediatrics 2012 12:168
  19. Children's fractures have been enlisted among orthopaedics complaints of childhood obesity. Unhealthy lifestyle behaviours may contribute to increased risk. This study described the prevalence of overweight/ob...

    Authors: Giuliana Valerio, Francesca Gallè, Caterina Mancusi, Valeria Di Onofrio, Pasquale Guida, Antonino Tramontano, Edoardo Ruotolo and Giorgio Liguori
    Citation: BMC Pediatrics 2012 12:166
  20. The number of new cases of type 1 diabetes mellitus (T1DM) has increased substantially in recent years and it is now one of the most common long-term endocrine disorders in childhood. In Sweden the child and f...

    Authors: Lisbeth Jönsson, Inger Hallström and Anita Lundqvist
    Citation: BMC Pediatrics 2012 12:165
  21. Human milk is the optimal nutrition for infants. When breastfeeding is not possible, supplementation of infant formula with long chain polyunsaturated fatty acids appears to promote neurodevelopmental outcome ...

    Authors: Maria Lorella Giannì, Paola Roggero, Charlotte Baudry, Amandine Ligneul, Daniela Morniroli, Francesca Garbarino, Pascale le Ruyet and Fabio Mosca
    Citation: BMC Pediatrics 2012 12:164
  22. Intestinal spirochetosis is an unusual infection in children and its clinical significance in humans is uncertain. The presence of these microorganisms in humans is well-known since the late 1800’s and was fir...

    Authors: Rossana Helbling, Maria-Chiara Osterheld, Bernard Vaudaux, Katia Jaton and Andreas Nydegger
    Citation: BMC Pediatrics 2012 12:163
  23. Anatomical progression of pediatric inflammatory bowel disease is under-reported. The aim of this work was to examine possible changes in the anatomical distribution of IBD in pediatric patients at diagnosis a...

    Authors: Jessica Tsang, Sheena Sikora, Donald Spady and Wael El-Matary
    Citation: BMC Pediatrics 2012 12:162
  24. An estimated 2.5 million children were living with HIV/AIDS at the end of 2009, 2.3 million (92%) in sub-Saharan Africa. Without treatment, a third of children with HIV will die of AIDS before their first birt...

    Authors: Digsu Negese Koye, Tadesse Awoke Ayele and Berihun Megabiaw Zeleke
    Citation: BMC Pediatrics 2012 12:161
  25. The Prevalence of liver disease among diabetics has been estimated to be between 17% and 100%. Most of these data were obtained from adult studies. The aim of our study was to screen for liver disease among ty...

    Authors: Abdulrahman A Al-Hussaini, Nimer M Sulaiman, Musa D AlZahrani, Ahmed S Alenizi and Mannan Khan
    Citation: BMC Pediatrics 2012 12:160
  26. Reducing neonatal death has been an emerging challenge in low and middle income countries in the past decade. The development of the low cost interventions and their effective delivery are needed to reduce dea...

    Authors: Ashish KC, Mats Målqvist, Johan Wrammert, Sheela Verma, Dhan Raj Aryal, Robert Clark, Naresh P KC, Ravi Vitrakoti, Kedar Baral and Uwe Ewald
    Citation: BMC Pediatrics 2012 12:159
  27. The Responsive Interdisciplinary Child-Community Health Education and Research (RICHER) initiative is an intersectoral and interdisciplinary community outreach primary health care (PHC) model. It is being unde...

    Authors: Sabrina T Wong, M Judith Lynam, Koushambhi B Khan, Lorine Scott and Christine Loock
    Citation: BMC Pediatrics 2012 12:158
  28. Human milk contains immune molecules involved in the protection of newborns against infections. We analyzed the concentration of Deleted in Malignant Brain Tumors 1 (DMBT1), a protein with functions in innate ...

    Authors: Sebastian Ronellenfitsch, Christel Weiß, David Frommhold, Lutz Koch, Jan Mollenhauer, Johannes Poeschl and Hanna Müller
    Citation: BMC Pediatrics 2012 12:157
  29. Currently over 50% of drugs prescribed to children have not been evaluated properly for use in their age group. One key reason why children have been excluded from clinical trials is that they are not consider...

    Authors: Irma M Hein, Pieter W Troost, Robert Lindeboom, Martine C de Vries, C Michel Zwaan and Ramón J L Lindauer
    Citation: BMC Pediatrics 2012 12:156
  30. Cerebral sparganosis in children is an extremely rare disease of central nervous system, and caused by a tapeworm larva from the genus of Spirometra. In this study, we discussed and summarized epidemiological,...

    Authors: Caigui Gong, Weihua Liao, Ashley Chineah, Xiaoyi Wang and Bob L Hou
    Citation: BMC Pediatrics 2012 12:155
  31. A critical factor shaping parental attitudes to vaccination is the parent’s interactions with health professionals. An effective interaction can address the concerns of vaccine supportive parents and motivate ...

    Authors: Julie Leask, Paul Kinnersley, Cath Jackson, Francine Cheater, Helen Bedford and Greg Rowles
    Citation: BMC Pediatrics 2012 12:154
  32. The Institute of Medicine has prioritized shared decision making (SDM), yet little is known about the impact of SDM over time on behavioral outcomes for children. This study examined the longitudinal associati...

    Authors: Alexander G Fiks, Stephanie Mayne, A Russell Localio, Chris Feudtner, Evaline A Alessandrini and James P Guevara
    Citation: BMC Pediatrics 2012 12:153
  33. To assess initial efficacy and feasibility of a structured behavioural group training (DELFIN) for parents of children with diabetes type 1, in order to reduce parenting stress and to improve parenting skills.

    Authors: Heike Saßmann, Mira de Hair, Thomas Danne and Karin Lange
    Citation: BMC Pediatrics 2012 12:152
  34. There are few reports on the nutritional status of Bhutanese children. The objective of this paper is to summarize results from the 2008 National Nutrition Survey and to describe progress achieved during the l...

    Authors: Ugyen Zangmo, Mercedes de Onis and Tandin Dorji
    Citation: BMC Pediatrics 2012 12:151
  35. The ATP7A gene encodes the ATP7A protein, which is a trans-Golgi network copper transporter expressed in the brain and other organs. Mutations in this gene cause disorders of copper metabolism, such as Menkes dis...

    Authors: Gregorio León-García, Alfredo Santana, Nicolás Villegas-Sepúlveda, Concepción Pérez-González, José M Henrríquez-Esquíroz, Carlota de León-García, Carlos Wong and Isabel Baeza
    Citation: BMC Pediatrics 2012 12:150
  36. The World Health Organization (WHO) is in the process of establishing a new global database on the growth of school children and adolescents. Limited national data exist from Asian children, notably those livi...

    Authors: Marjan Mansourian, Hamid Reza Marateb, Roya Kelishadi, Mohammad Esmaeil Motlagh, Tahereh Aminaee, Mahnaz Taslimi, Reza Majdzadeh, Ramin Heshmat, Gelayol Ardalan and Parinaz Poursafa
    Citation: BMC Pediatrics 2012 12:149
  37. The frequency of preterm labour has risen over the last few years. Hence, there is growing interest in the identification of markers that may facilitate prediction and prevention of premature birth complicatio...

    Authors: Maciej Kotowski, Krzysztof Safranow, Miłosz P Kawa, Joanna Lewandowska, Patrycja Kłos, Violetta Dziedziejko, Edyta Paczkowska, Ryszard Czajka, Zbigniew Celewicz, Jacek Rudnicki and Bogusław Machaliński
    Citation: BMC Pediatrics 2012 12:148
  38. Follow up of Human Immunodeficiency Virus (HIV)-exposed infants is an important component of Prevention of Mother-to-Child Transmission (PMTCT) programmes in order to ascertain infant outcomes post delivery. W...

    Authors: Terusha Chetty, Stephen Knight, Janet Giddy, Tamaryn L Crankshaw, Lisa M Butler and Marie-Louise Newell
    Citation: BMC Pediatrics 2012 12:146
  39. Despite progresses in neonatal care, the mortality and the incidence of neuro-motor disability after perinatal asphyxia have failed to show substantial improvements. In countries with a high level of perinatal...

    Authors: Luca Filippi, Patrizio Fiorini, Marta Daniotti, Serena Catarzi, Sara Savelli, Claudio Fonda, Laura Bartalena, Antonio Boldrini, Matteo Giampietri, Rosa Scaramuzzo, Paola Papoff, Francesca Del Balzo, Alberto Spalice, Giancarlo la Marca, Sabrina Malvagia, Maria Luisa Della Bona…
    Citation: BMC Pediatrics 2012 12:144
  40. Adolescence is characterized by marked psychosocial, behavioural and biological changes and represents a critical life transition through which adult health and well-being are established. Substantial research...

    Authors: Katharine Steinbeck, Philip Hazell, Robert G Cumming, S Rachel Skinner, Rebecca Ivers, Robert Booy, Greg Fulcher, David J Handelsman, Andrew J Martin, Geoff Morgan, Jean Starling, Adrian Bauman, Margot L Rawsthorne, David L Bennett, Chin Moi Chow, Mary K Lam…
    Citation: BMC Pediatrics 2012 12:143
  41. Necrotizing enterocolitis (NEC) is a disease in neonates, often resulting in death or serious medical or neurodevelopmental complications. The rate of NEC is highest in the smallest babies and many efforts hav...

    Authors: Chelsea Hunter, Mary Ann VT Dimaguila, Peter Gal, John E Wimmer Jr, James Laurence Ransom, Rita Q Carlos, McCrae Smith and Christie C Davanzo
    Citation: BMC Pediatrics 2012 12:142
  42. Although the links between poverty and health have often been studied , the dynamics of poverty and physical health in early childhood remain under-investigated. In particular, it is not known whether the heal...

    Authors: Nikiéma Béatrice, Gauvin Lise, Zunzunegui Maria Victoria and Séguin Louise
    Citation: BMC Pediatrics 2012 12:141

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