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  1. Adverse cardiorespiratory events including apnea, bradycardia, and desaturations have been described following administration of the first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae typ...

    Authors: Jackie Lee, Joan L Robinson and Donald W Spady

    Citation: BMC Pediatrics 2006 6:20

    Content type: Research article

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  2. In view of the fact that a significant proportion of neonates with malaria may be missed on our wards on the assumption that the disease condition is rare, this study aims at documenting the prevalence of mala...

    Authors: Iyabo T Runsewe-Abiodun, Olusoga B Ogunfowora and Bolanle M Fetuga

    Citation: BMC Pediatrics 2006 6:19

    Content type: Research article

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  3. To determine the validity of the recently developed child-specific thoracic gas volume (TGV) prediction equations for use in air-displacement plethysmography (ADP) in diverse pediatric populations.

    Authors: Paul B Higgins, Analiza M Silva, Luis B Sardinha, Holly R Hull, Michael I Goran, Barbara A Gower and David A Fields

    Citation: BMC Pediatrics 2006 6:18

    Content type: Research article

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  4. It has recently been suggested that serum procalcitonin (PCT) is of value in the diagnosis of neonatal sepsis, with varying results. The aim of this prospective multicenter study was to assess the usefulness o...

    Authors: José B López Sastre, David Pérez Solís, Vicente Roqués Serradilla, Belén Fernández Colomer, Gil D Coto Cotallo, Xavier Krauel Vidal, Eduardo Narbona López, Manuel García del Río, Manuel Sánchez Luna, Antonio Belaustegui Cueto, Manuel Moro Serrano, Alfonso Urbón Artero, Emilio Álvaro Iglesias, Ángel Cotero Lavín, Eduardo Martínez Vilalta and Bartolomé Jiménez Cobos

    Citation: BMC Pediatrics 2006 6:16

    Content type: Research article

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  5. The patent ductus arteriosus (PDA) is an important problem in premature infants. Surgical PDA ligation is usually only be considered when medical treatment has either failed or was contraindicated. The aims of...

    Authors: LLeona CL Lee, Angela Tillett, Robert Tulloh, Robert Yates and Wilf Kelsall

    Citation: BMC Pediatrics 2006 6:15

    Content type: Research article

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  6. The hard edges of adult finger clip probes of the pulse oximetry oxygen saturation (POOS) monitor can cause skin damage if used for prolonged periods in a neonate. Covering the skin under the probe with Microp...

    Authors: Jyotsna James, Lokesh Tiwari, Pramod Upadhyay, Vishnubhatla Sreenivas, Vikas Bhambhani and Jacob M Puliyel

    Citation: BMC Pediatrics 2006 6:14

    Content type: Research article

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  7. ACOG states meconium stained amniotic fluid (MSAF) as one of the historical indicators of perinatal asphyxia. Thick meconium along with other indicators is used to identify babies with severe intrapartum asphy...

    Authors: Rishi Kant Ojha, Saroj K Singh, Sanjay Batra, V Sreenivas and Jacob M Puliyel

    Citation: BMC Pediatrics 2006 6:13

    Content type: Research article

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  8. Thyroid hormone plays a crucial role in the growth and function of the central nervous system. The purpose of the study was to examine the relationships between the status of subclinical thyroid conditions and...

    Authors: Tiejian Wu, Joanne W Flowers, Fred Tudiver, Jim L Wilson and Natavut Punyasavatsut

    Citation: BMC Pediatrics 2006 6:12

    Content type: Research article

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  9. SRY (sex-determining region, Y) is the gene responsible of gonadal differentiation in the male and it is essential for the regular development of male genitalia. Translocations involving the human sex chromosome...

    Authors: M Ellaithi, D Gisselsson, T Nilsson, S Abd El-Fatah, T Ali, A Elagib, ME Ibrahim and I Fadl-Elmula

    Citation: BMC Pediatrics 2006 6:11

    Content type: Case report

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  10. We aimed to investigate incidence rates of urinary tract infections in Dutch general practice and their association with gender, season and urbanisation level, and to analyse prescription and referral in case ...

    Authors: Wing-Yee Kwok, Marjolein CE de Kwaadsteniet, Mirjam Harmsen, Lisette WA van Suijlekom-Smit, François G Schellevis and Johannes C van der Wouden

    Citation: BMC Pediatrics 2006 6:10

    Content type: Research article

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  11. The contribution of birth defects, including cleft lip and palate, to neonatal and infant mortality and morbidity is substantial. As other mortality and morbidity causes including infections, hygiene, prematur...

    Authors: George L Wehby, Eduardo E Castilla, Norman Goco, Monica Rittler, Viviana Cosentino, Lorette Javois, Ann Marie McCarthy, Georgiy Bobashev, Stephen Litavecz, Alejandra Mariona, Graca Dutra, Jorge S López-Camelo, Iêda M Orioli and Jeffrey C Murray

    Citation: BMC Pediatrics 2006 6:9

    Content type: Study protocol

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  12. Monitoring plasma gentamicin concentrations in neonates 24 hours after a once daily dose (4 mg/kg) often necessitates additional blood sampling. In adults a nomogram has been developed enabling evaluation of g...

    Authors: Elaine M Boyle, Isobel Brookes, Kathy Nye, Mike Watkinson and F Andrew I Riordan

    Citation: BMC Pediatrics 2006 6:8

    Content type: Research article

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  13. Early detection and treatment of neonatal hyperbilirubinemia is important in the prevention of bilirubin-induced encephalopathy. In this study, we evaluated the New Jersey pediatricians' practices and beliefs ...

    Authors: Anna Petrova, Rajeev Mehta, Gillian Birchwood, Barbara Ostfeld and Thomas Hegyi

    Citation: BMC Pediatrics 2006 6:6

    Content type: Research article

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  14. Bacille Calmette-Guérin (BCG) vaccine is given to Canadian Aboriginal neonates in selected communities. Severe reactions and deaths associated with BCG have been reported among infants born with immunodeficien...

    Authors: Michael Clark and D William Cameron

    Citation: BMC Pediatrics 2006 6:5

    Content type: Research article

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  15. There are no prospective studies that have examined for chronic cough in children without lung disease but with gastroesophageal reflux (GER). In otherwise healthy children undergoing flexible upper gastrointe...

    Authors: Anne B Chang, Nancy C Cox, Joan Faoagali, Geoffrey J Cleghorn, Christopher Beem, Looi C Ee, Geoffrey D Withers, Mark K Patrick and Peter J Lewindon

    Citation: BMC Pediatrics 2006 6:4

    Content type: Research article

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  16. Our primary purpose was to determine the normal range and variability of blood volume (BV) in healthy children, in order to provide reference values during childhood and adolescence. Our secondary aim was to c...

    Authors: Ann Raes, Sarah Van Aken, Margarita Craen, Raymond Donckerwolcke and Johan Vande Walle

    Citation: BMC Pediatrics 2006 6:3

    Content type: Research article

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  17. Recent reports have documented a leveling-off of survival rates in preterm infants through the 1990's. The objective of this study was to determine temporal changes in illness severity in very low birth weight...

    Authors: David A Paul, Kathleen H Leef, Robert G Locke, Louis Bartoshesky, Judy Walrath and John L Stefano

    Citation: BMC Pediatrics 2006 6:2

    Content type: Research article

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  18. A number of infant pain measures have been developed over the past 15 years incorporating behavioural and physiologic indicators; however, no reliable or valid measure exists for infants who are at risk for ne...

    Authors: Bonnie Stevens, Patrick McGrath, Janet Yamada, Sharyn Gibbins, Joseph Beyene, Lynn Breau, Carol Camfield, Allen Finley, Linda Franck, Alexandra Howlett, Celeste Johnston, Patricia McKeever, Karel O'Brien and Arne Ohlsson

    Citation: BMC Pediatrics 2006 6:1

    Content type: Research article

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  19. Coagulase negative staphylococcus (CONS) is the main cause of late-onset sepsis in Neonatal Intensive Care Units (NICU). Although CONS rarely causes fulminant sepsis, vancomycin is frequently used as empiric t...

    Authors: Sarah L Lawrence, Virginia Roth, Robert Slinger, Baldwin Toye, Isabelle Gaboury and Brigitte Lemyre

    Citation: BMC Pediatrics 2005 5:49

    Content type: Research article

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  20. The condition of obesity has become a significant public health problem in the United States. In children and adolescents, the prevalence of overweight has tripled in the last 20 years, with approximately 16.0...

    Authors: Carol Curtin, Linda G Bandini, Ellen C Perrin, David J Tybor and Aviva Must

    Citation: BMC Pediatrics 2005 5:48

    Content type: Research article

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  21. Subacute Sclerosing Panencephalitis (SSPE) is so rare in developed countries with measles immunization programs that national active surveillance is now needed to capture sufficient number of cases for meaning...

    Authors: Craig Campbell, Simon Levin, Peter Humphreys, Wikke Walop and Renee Brannan

    Citation: BMC Pediatrics 2005 5:47

    Content type: Research article

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  22. Anaemia is highly prevalent in children of developing countries. It is associated with impaired physical growth and mental development. Palmar pallor is recommended at primary level for diagnosing it, on the b...

    Authors: Juan P Chalco, Luis Huicho, Carlos Alamo, Nilton Y Carreazo and Carlos A Bada

    Citation: BMC Pediatrics 2005 5:46

    Content type: Research article

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  23. Care procedures for preventing neonatal diseases are carried out according to nurseries' traditions and may be not consistent with the evidence based medicine issues.

    Authors: Andrea Guala, Roberta Guarino, Mauro Zaffaroni, Claudio Martano, Claudio Fabris, Guido Pastore and Gianni Bona

    Citation: BMC Pediatrics 2005 5:45

    Content type: Research article

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  24. The introduction of pneumococcal conjugate vaccine (PCV) to the U.S. recommended childhood immunization schedule in the year 2000 added three injections to the number of vaccinations a child is expected to rec...

    Authors: Nancy D Lin, Ken Kleinman, K Arnold Chan, Xian-Jie Yu, Eric K France, Stanley Xu, Feifei Wei, John Mullooly, Jeanne Santoli and Tracy A Lieu

    Citation: BMC Pediatrics 2005 5:43

    Content type: Research article

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  25. The Complete Blood Count (CBC) is a test frequently performed on children presenting to the Pediatric Emergency Department (PED), usually for the evaluation of an infectious illness. The CBC also allows for sc...

    Authors: Martin V Pusic, Brenda J Dawyduk and David Mitchell

    Citation: BMC Pediatrics 2005 5:42

    Content type: Research article

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  26. The increased survival of preterm and very low birth weight infants in recent years has been well documented but continued surveillance is required in order to monitor the effects of new therapeutic interventi...

    Authors: Huw P Jones, Stella Karuri, Catherine MG Cronin, Arne Ohlsson, Abraham Peliowski, Anne Synnes and Shoo K Lee

    Citation: BMC Pediatrics 2005 5:40

    Content type: Research article

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  27. Bronchitis obliterans is a severe and extremely rare complication of respiratory tract infections in children and is characterized by massive atelectasis and collapse of the affected lung. Of the rare cases re...

    Authors: Elke Govaere, Dirk Van Raemdonck, Hugo Devlieger, Maria-Helena Smet, Eric Verbeken, Marijke Proesmans and Kris De Boeck

    Citation: BMC Pediatrics 2005 5:39

    Content type: Case report

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  28. The delivery of optimal medical care to children is dependent on the availability of child relevant research. Our objectives were to: i) systematically review and describe how children are handled in reviews o...

    Authors: Kristie Cramer, Natasha Wiebe, Virginia Moyer, Lisa Hartling, Katrina Williams, George Swingler and Terry P Klassen

    Citation: BMC Pediatrics 2005 5:38

    Content type: Research article

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  29. The antipyretic effectiveness of rectal versus oral acetaminophen is not well established. This study is designed to compare the antipyretic effectiveness of two rectal acetaminophen doses (15 mg/kg) and (35 m...

    Authors: Mona Nabulsi, Hala Tamim, Ramzi Sabra, Ziyad Mahfoud, Shadi Malaeb, Hadi Fakih and Mohammad Mikati

    Citation: BMC Pediatrics 2005 5:35

    Content type: Research article

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  30. Tourette Syndrome (TS) is a neurodevelopmental disorder of childhood. Learning disabilities are frequently comorbid with TS. Using the largest sample of TS patients ever reported, we sought to identify differe...

    Authors: Larry Burd, Roger D Freeman, Marilyn G Klug and Jacob Kerbeshian

    Citation: BMC Pediatrics 2005 5:34

    Content type: Research article

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  31. Because there are no child-friendly, validated, self-report measures of dyspnea or breathlessness, we developed, and provided initial validation, of three, 7-item, pictorial scales depicting three sub-construc...

    Authors: Patrick J McGrath, Paul T Pianosi, Anita M Unruh and Chloe P Buckley

    Citation: BMC Pediatrics 2005 5:33

    Content type: Research article

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  32. Spina Bifida (SB) is the second most common birth defect worldwide. Since the chances of survival in children with severe SB-forms have increased, medical care has shifted its emphasis from life-saving interve...

    Authors: Ignace PR Vermaes, Jan MAM Janssens, Anna MT Bosman and Jan RM Gerris

    Citation: BMC Pediatrics 2005 5:32

    Content type: Research article

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  33. Acute viral bronchiolitis is one of the most common causes of hospitalisation during infancy in our region with respiratory syncytial virus (RSV) historically being the major causative agent. Many infants with...

    Authors: Hans-Olav Fjærli, Teresa Farstad, Gisle Rød, Gunn Kristin Ufert, Pål Gulbrandsen and Britt Nakstad

    Citation: BMC Pediatrics 2005 5:31

    Content type: Research article

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  34. PCO2 and PO2 are important monitoring parameters in neonatal intensive care units (NICU). Compared to conventional blood gas measurements that cause significant blood loss in preterms, transcutaneous (tc) measure...

    Authors: Mario Rüdiger, Kerstin Töpfer, Hannes Hammer, Gerd Schmalisch and Roland R Wauer

    Citation: BMC Pediatrics 2005 5:30

    Content type: Research article

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  35. Iron supplementation may be associated with oxidative stress particularly in premature infants. Our purpose was to examine 1) early supplemental iron during treatment with erythropoietin (EPO) and oxidative st...

    Authors: James K Friel, Khalid Aziz, Wayne L Andrews and Robert E Serfass

    Citation: BMC Pediatrics 2005 5:29

    Content type: Research article

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  36. Little is known about the factors that predispose to the occurrence and severity of cardio-respiratory symptoms during the placement of a prematurely born infant in a car seat. The impact of gestational age, w...

    Authors: Vallier C Ojadi, Anna Petrova, Rajeev Mehta and Thomas Hegyi

    Citation: BMC Pediatrics 2005 5:28

    Content type: Research article

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  37. Middle ear disease (otitis media) is common and frequently severe in Australian Aboriginal children. There have not been any recent large-scale surveys using clear definitions and a standardised middle ear ass...

    Authors: Peter S Morris, Amanda J Leach, Peter Silberberg, Gabrielle Mellon, Cate Wilson, Elizabeth Hamilton and Jemima Beissbarth

    Citation: BMC Pediatrics 2005 5:27

    Content type: Research article

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  38. Improved survival due to advances in neonatal care has brought issues such as postnatal growth and development more to the focus of our attention. Most studies report stunting in children born very preterm and...

    Authors: Noël BB Knops, Kommer CA Sneeuw, Ronald Brand, Elysee TM Hille, A Lya den Ouden, Jan-Maarten Wit and S Pauline Verloove-Vanhorick

    Citation: BMC Pediatrics 2005 5:26

    Content type: Research article

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  39. In children with severe generalized cerebral palsy, pneumonias are a major health issue. Malnutrition, dysphagia, gastro-oesophageal reflux, impaired respiratory function and constipation are hypothesized risk...

    Authors: Rebekka Veugelers, Elsbeth AC Calis, Corine Penning, Arianne Verhagen, Roos Bernsen, Jan Bouquet, Marc A Benninga, Peter JFM Merkus, Hubertus GM Arets, Dick Tibboel and Heleen M Evenhuis

    Citation: BMC Pediatrics 2005 5:25

    Content type: Study protocol

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  40. Gastroesophageal reflux disease (GERD) is believed to be more common in adult males as compared to females. It also has been shown in adults to be more common in Caucasians. We wanted to determine ethnicity an...

    Authors: Dena Nazer, Ronald Thomas and Vasundhara Tolia

    Citation: BMC Pediatrics 2005 5:24

    Content type: Research article

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  41. Information is lacking on the effects of congenital toxoplasmosis on development, behavior, and impairment in later childhood, as well as on parental concerns and anxiety. This information is important for cou...

    Authors: Katherine Freeman, Alison Salt, Andrea Prusa, Gunilla Malm, Nicole Ferret, Wilma Buffolano, Dorthe Schmidt, Hooi Kuan Tan and Ruth E Gilbert

    Citation: BMC Pediatrics 2005 5:23

    Content type: Research article

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  42. Nosocomial infection (NI), particularly with positive blood or cerebrospinal fluid bacterial cultures, is a major cause of morbidity in neonatal intensive care units (NICUs). Rates of NI appear to vary substan...

    Authors: Khalid Aziz, Douglas D McMillan, Wayne Andrews, Margaret Pendray, Zhenguo Qiu, Stella Karuri and Shoo K Lee

    Citation: BMC Pediatrics 2005 5:22

    Content type: Research article

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  43. We aimed to determine how response to a parent-completed postal questionnaire measuring development, behaviour, impairment, and parental concerns and anxiety, varies in different European centres.

    Authors: A Salt, K Freeman, A Prusa, N Ferret, W Buffolano, G Malm, D Schmidt, HK Tan and RE Gilbert

    Citation: BMC Pediatrics 2005 5:21

    Content type: Research article

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  44. Induced mutagenesis in utero is likely to have life-long repercussions for the exposed fetus, affecting survival, birth weight and susceptibility to both childhood and adult-onset diseases, such as cancer. In the...

    Authors: Stephen G Grant

    Citation: BMC Pediatrics 2005 5:20

    Content type: Research article

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