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  1. Many studies in sub-Saharan Africa have occasionally reported a higher prevalence of stunting in male children compared to female children. This study examined whether there are systematic sex differences in s...

    Authors: Henry Wamani, Anne Nordrehaug Åstrøm, Stefan Peterson, James K Tumwine and Thorkild Tylleskär

    Citation: BMC Pediatrics 2007 7:17

    Content type: Research article

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  2. In the past, effortful exercises were considered inappropriate for children with spastic cerebral palsy (CP) due to concern that they would escalate abnormalities including spasticity and abnormal movement pat...

    Authors: Eileen G Fowler, Loretta M Knutson, Sharon K DeMuth, Mia Sugi, Kara Siebert, Victoria Simms, Stanley P Azen and Carolee J Winstein

    Citation: BMC Pediatrics 2007 7:14

    Content type: Study protocol

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  3. Few studies address the use of paediatric highly active antiretroviral therapy (HAART) in Africa.

    Authors: Anand Reddi, Sarah C Leeper, Anneke C Grobler, Rosemary Geddes, K Holly France, Gillian L Dorse, Willem J Vlok, Mbali Mntambo, Monty Thomas, Kristy Nixon, Helga L Holst, Quarraisha Abdool Karim, Nigel C Rollins, Hoosen M Coovadia and Janet Giddy

    Citation: BMC Pediatrics 2007 7:13

    Content type: Research article

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  4. Delivery of tobramycin by inhalation to the lungs of patients with cystic fibrosis (CF) who are infected with Pseudomonas aeruginosa has been proven to be effective and safe. The aerosol administration allows hig...

    Authors: Roberto P Santos, Emad Awa and Ran D Anbar

    Citation: BMC Pediatrics 2007 7:11

    Content type: Case report

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  5. Exclusive breastfeeding is recommended as the best feeding alternative for infants up to six months and has a protective effect against mortality and morbidity. It also seems to lower HIV-1 transmission compar...

    Authors: Ingunn Marie S Engebretsen, Henry Wamani, Charles Karamagi, Nulu Semiyaga, James Tumwine and Thorkild Tylleskär

    Citation: BMC Pediatrics 2007 7:10

    Content type: Research article

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  6. The results of recent studies suggest the usefulness of PCT for early diagnosis of neonatal sepsis, with varying results. The aim of this prospective multicenter study was to determine the behavior of serum PC...

    Authors: José B López Sastre, David Pérez Solís, Vicente Roqués Serradilla, Belén Fernández Colomer and Gil D Coto Cotallo

    Citation: BMC Pediatrics 2007 7:9

    Content type: Research article

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  7. Factor V deficiency is a rare autosomal recessive coagulation disorder. Awareness of presenting features and management is important to avoid bleeding complications associated with mortality and neurodisability.

    Authors: Amol Chingale, Michael Eisenhut, Anjali Gadiraju and Ri Liesner

    Citation: BMC Pediatrics 2007 7:8

    Content type: Case report

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  8. Procedural pain relief is sub-optimal in neonates. Topical tetracaine provides pain relief in children. Evidence of its efficacy and safety in neonates is limited. The objective of this study was to assess the...

    Authors: Brigitte Lemyre, Debora L Hogan, Isabelle Gaboury, Rebecca Sherlock, Colline Blanchard and David Moher

    Citation: BMC Pediatrics 2007 7:7

    Content type: Research article

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  9. Brachmann de Lange syndrome (BDLS) is a multiple congenital anomaly syndrome characterized by a distinctive facial appearance, prenatal and postnatal growth deficiency, psychomotor delay, behavioral problems, ...

    Authors: Mona Ellaithi, David Gisselsson, Therese Nilsson, Atif Elagib, Imad Fadl-Elmula and Mashair Abdelgadir

    Citation: BMC Pediatrics 2007 7:6

    Content type: Case report

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  10. A standard contrast enema for Hirschsprung's disease can sometimes be inconclusive in delineating a transition zone especially in neonates and infants. The aim of this study was to determine the utility and di...

    Authors: Akshay Pratap, Devendra K Gupta, Awadhesh Tiwari, Arvind K Sinha, Nisha Bhatta, Satyendra N Singh, Chandra S Agrawal, Anand Kumar and Shailesh Adhikary

    Citation: BMC Pediatrics 2007 7:5

    Content type: Research article

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  11. Hypophosphatasia (HP) is characterized by a genetic defect in the tissue-nonspecific alkaline phosphatase (TNSALP) gene and predominantly an autosomal recessive trait. HP patients suffer from reduced bone mine...

    Authors: Hermann J Girschick, Etienne Mornet, Meinrad Beer, Monika Warmuth-Metz and Peter Schneider

    Citation: BMC Pediatrics 2007 7:3

    Content type: Case report

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  12. Documentation of superfoetation is extremely rare in humans., The younger foetus has invariably been small for gestational age (estimated from the date of the last menstrual bleed) in all the cases reported in...

    Authors: Noopur Baijal, Mohit Sahni, Neeraj Verma, Amit Kumar, Nittin Parkhe and Jacob M Puliyel

    Citation: BMC Pediatrics 2007 7:2

    Content type: Case report

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  13. Implementation of health research findings is important for medicine to be evidence-based. Previous studies have found variation in the information sources thought to be of greatest importance to clinicians bu...

    Authors: Teresa H Jones, Steve Hanney and Martin J Buxton

    Citation: BMC Pediatrics 2007 7:1

    Content type: Research article

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  14. Researchers and clinicians are seeking to develop efficacious behavioral interventions to treat overweight children; however, few studies have documented the behavioral correlates of overweight children in com...

    Authors: Shelagh A Mulvaney, Kristine L Kaemingk, James L Goodwin and Stuart F Quan

    Citation: BMC Pediatrics 2006 6:34

    Content type: Research article

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  15. The purpose of this study was to determine the prevalence of high blood pressure (HBP) and associated risk factors in school children 8 to 13 years of age.

    Authors: Ximena Urrutia-Rojas, Christie U Egbuchunam, Sejong Bae, John Menchaca, Manuel Bayona, Patrick A Rivers and Karan P Singh

    Citation: BMC Pediatrics 2006 6:32

    Content type: Research article

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  16. In 1999, the American Academy of Pediatrics and U.S. Public Health Service recommended suspending the birth dose of hepatitis B vaccine due to concerns about potential mercury exposure. A previous report found...

    Authors: Nancy D Lin, Ken Kleinman, K Arnold Chan, Xian-Jie Yu, Eric K France, Feifei Wei, John P Mullooly, Steven Black, David K Shay, Margarette Kolczak and Tracy A Lieu

    Citation: BMC Pediatrics 2006 6:31

    Content type: Research article

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  17. Childhood injury is the leading cause of mortality, morbidity and permanent disability in children in the developed world. This research examines relationships between socio-economic status (SES), demographics...

    Authors: Susan J Gilbride, Cameron Wild, Douglas R Wilson, Lawrence W Svenson and Donald W Spady

    Citation: BMC Pediatrics 2006 6:30

    Content type: Research article

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  18. Because of the paucity of effective evidence-based therapies for children with recurrent abdominal pain, we evaluated the therapeutic effect of guided imagery, a well-studied self-regulation technique.

    Authors: Joy A Weydert, Daniel E Shapiro, Sari A Acra, Cynthia J Monheim, Andrea S Chambers and Thomas M Ball

    Citation: BMC Pediatrics 2006 6:29

    Content type: Research article

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  19. Point of care (POC) glucose meters are routinely used as a screening tool for hypoglycemia in a neonatal setting. Glucose meters however, lack the same accuracy as laboratory instruments for glucose measuremen...

    Authors: Cynthia Balion, Vijaylaxmi Grey, Afisi Ismaila, Susan Blatz and Wendy Seidlitz

    Citation: BMC Pediatrics 2006 6:28

    Content type: Research article

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  20. For centuries, sunlight has been used for therapeutic purposes. Parents still sun their infants to treat neonatal jaundice, nappy rash or mostly to supply vitamin D for bone development as a consequence of hea...

    Authors: Nihal Aladag, Tuncay M Filiz, Pinar Topsever and Suleyman Gorpelioglu

    Citation: BMC Pediatrics 2006 6:27

    Content type: Research article

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  21. Our goal was to quantify the evidence that is available to the physicians of a pediatric emergency department (PED) in making treatment decisions. Further, we wished to ascertain what percentage of evidence fo...

    Authors: Kellie L Waters, Natasha Wiebe, Kristie Cramer, Lisa Hartling and Terry P Klassen

    Citation: BMC Pediatrics 2006 6:26

    Content type: Research article

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  22. Cystic fibrosis (CF) is caused by mutations in the gene encoding for the CF transmembrane conductance regulator (CFTR) protein, which acts as a chloride channel after activation by cyclic AMP (cAMP). Newborn s...

    Authors: Isabelle Sermet-Gaudelus, Delphine Roussel, Stéphanie Bui, Eric Deneuville, Frédéric Huet, Philippe Reix, Gabriel Bellon, Gérard Lenoir and Aleksander Edelman

    Citation: BMC Pediatrics 2006 6:25

    Content type: Study protocol

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  23. Birth weight is a composite of skeletal size and soft tissue. These components are likely to have different growth patterns. The aim of this paper is to investigate the association between established determin...

    Authors: Beverley M Shields, Bridget A Knight, Roy J Powell, Andrew T Hattersley and David E Wright

    Citation: BMC Pediatrics 2006 6:24

    Content type: Research article

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  24. Previous studies regarding the use of information technologies (IT) specifically among pediatricians and other physicians who treat children are lacking. As such, the objective of this study is to examine the ...

    Authors: Nir Menachemi, Donna L Ettel, Robert G Brooks and Lisa Simpson

    Citation: BMC Pediatrics 2006 6:21

    Content type: Research article

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  25. Adverse cardiorespiratory events including apnea, bradycardia, and desaturations have been described following administration of the first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae typ...

    Authors: Jackie Lee, Joan L Robinson and Donald W Spady

    Citation: BMC Pediatrics 2006 6:20

    Content type: Research article

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  26. In view of the fact that a significant proportion of neonates with malaria may be missed on our wards on the assumption that the disease condition is rare, this study aims at documenting the prevalence of mala...

    Authors: Iyabo T Runsewe-Abiodun, Olusoga B Ogunfowora and Bolanle M Fetuga

    Citation: BMC Pediatrics 2006 6:19

    Content type: Research article

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  27. To determine the validity of the recently developed child-specific thoracic gas volume (TGV) prediction equations for use in air-displacement plethysmography (ADP) in diverse pediatric populations.

    Authors: Paul B Higgins, Analiza M Silva, Luis B Sardinha, Holly R Hull, Michael I Goran, Barbara A Gower and David A Fields

    Citation: BMC Pediatrics 2006 6:18

    Content type: Research article

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  28. It has recently been suggested that serum procalcitonin (PCT) is of value in the diagnosis of neonatal sepsis, with varying results. The aim of this prospective multicenter study was to assess the usefulness o...

    Authors: José B López Sastre, David Pérez Solís, Vicente Roqués Serradilla, Belén Fernández Colomer, Gil D Coto Cotallo, Xavier Krauel Vidal, Eduardo Narbona López, Manuel García del Río, Manuel Sánchez Luna, Antonio Belaustegui Cueto, Manuel Moro Serrano, Alfonso Urbón Artero, Emilio Álvaro Iglesias, Ángel Cotero Lavín, Eduardo Martínez Vilalta and Bartolomé Jiménez Cobos

    Citation: BMC Pediatrics 2006 6:16

    Content type: Research article

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  29. The patent ductus arteriosus (PDA) is an important problem in premature infants. Surgical PDA ligation is usually only be considered when medical treatment has either failed or was contraindicated. The aims of...

    Authors: LLeona CL Lee, Angela Tillett, Robert Tulloh, Robert Yates and Wilf Kelsall

    Citation: BMC Pediatrics 2006 6:15

    Content type: Research article

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  30. The hard edges of adult finger clip probes of the pulse oximetry oxygen saturation (POOS) monitor can cause skin damage if used for prolonged periods in a neonate. Covering the skin under the probe with Microp...

    Authors: Jyotsna James, Lokesh Tiwari, Pramod Upadhyay, Vishnubhatla Sreenivas, Vikas Bhambhani and Jacob M Puliyel

    Citation: BMC Pediatrics 2006 6:14

    Content type: Research article

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  31. ACOG states meconium stained amniotic fluid (MSAF) as one of the historical indicators of perinatal asphyxia. Thick meconium along with other indicators is used to identify babies with severe intrapartum asphy...

    Authors: Rishi Kant Ojha, Saroj K Singh, Sanjay Batra, V Sreenivas and Jacob M Puliyel

    Citation: BMC Pediatrics 2006 6:13

    Content type: Research article

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  32. Thyroid hormone plays a crucial role in the growth and function of the central nervous system. The purpose of the study was to examine the relationships between the status of subclinical thyroid conditions and...

    Authors: Tiejian Wu, Joanne W Flowers, Fred Tudiver, Jim L Wilson and Natavut Punyasavatsut

    Citation: BMC Pediatrics 2006 6:12

    Content type: Research article

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  33. SRY (sex-determining region, Y) is the gene responsible of gonadal differentiation in the male and it is essential for the regular development of male genitalia. Translocations involving the human sex chromosome...

    Authors: M Ellaithi, D Gisselsson, T Nilsson, S Abd El-Fatah, T Ali, A Elagib, ME Ibrahim and I Fadl-Elmula

    Citation: BMC Pediatrics 2006 6:11

    Content type: Case report

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  34. We aimed to investigate incidence rates of urinary tract infections in Dutch general practice and their association with gender, season and urbanisation level, and to analyse prescription and referral in case ...

    Authors: Wing-Yee Kwok, Marjolein CE de Kwaadsteniet, Mirjam Harmsen, Lisette WA van Suijlekom-Smit, François G Schellevis and Johannes C van der Wouden

    Citation: BMC Pediatrics 2006 6:10

    Content type: Research article

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  35. The contribution of birth defects, including cleft lip and palate, to neonatal and infant mortality and morbidity is substantial. As other mortality and morbidity causes including infections, hygiene, prematur...

    Authors: George L Wehby, Eduardo E Castilla, Norman Goco, Monica Rittler, Viviana Cosentino, Lorette Javois, Ann Marie McCarthy, Georgiy Bobashev, Stephen Litavecz, Alejandra Mariona, Graca Dutra, Jorge S López-Camelo, Iêda M Orioli and Jeffrey C Murray

    Citation: BMC Pediatrics 2006 6:9

    Content type: Study protocol

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  36. Monitoring plasma gentamicin concentrations in neonates 24 hours after a once daily dose (4 mg/kg) often necessitates additional blood sampling. In adults a nomogram has been developed enabling evaluation of g...

    Authors: Elaine M Boyle, Isobel Brookes, Kathy Nye, Mike Watkinson and F Andrew I Riordan

    Citation: BMC Pediatrics 2006 6:8

    Content type: Research article

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  37. Early detection and treatment of neonatal hyperbilirubinemia is important in the prevention of bilirubin-induced encephalopathy. In this study, we evaluated the New Jersey pediatricians' practices and beliefs ...

    Authors: Anna Petrova, Rajeev Mehta, Gillian Birchwood, Barbara Ostfeld and Thomas Hegyi

    Citation: BMC Pediatrics 2006 6:6

    Content type: Research article

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  38. Bacille Calmette-Guérin (BCG) vaccine is given to Canadian Aboriginal neonates in selected communities. Severe reactions and deaths associated with BCG have been reported among infants born with immunodeficien...

    Authors: Michael Clark and D William Cameron

    Citation: BMC Pediatrics 2006 6:5

    Content type: Research article

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  39. There are no prospective studies that have examined for chronic cough in children without lung disease but with gastroesophageal reflux (GER). In otherwise healthy children undergoing flexible upper gastrointe...

    Authors: Anne B Chang, Nancy C Cox, Joan Faoagali, Geoffrey J Cleghorn, Christopher Beem, Looi C Ee, Geoffrey D Withers, Mark K Patrick and Peter J Lewindon

    Citation: BMC Pediatrics 2006 6:4

    Content type: Research article

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  40. Our primary purpose was to determine the normal range and variability of blood volume (BV) in healthy children, in order to provide reference values during childhood and adolescence. Our secondary aim was to c...

    Authors: Ann Raes, Sarah Van Aken, Margarita Craen, Raymond Donckerwolcke and Johan Vande Walle

    Citation: BMC Pediatrics 2006 6:3

    Content type: Research article

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  41. Recent reports have documented a leveling-off of survival rates in preterm infants through the 1990's. The objective of this study was to determine temporal changes in illness severity in very low birth weight...

    Authors: David A Paul, Kathleen H Leef, Robert G Locke, Louis Bartoshesky, Judy Walrath and John L Stefano

    Citation: BMC Pediatrics 2006 6:2

    Content type: Research article

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