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  1. Although a number of studies have shown good results in treating children with antiretroviral drugs (ARVs) in hospital settings, there is limited published information on results in pediatric programs that are...

    Authors: Johan van Griensven, Ludwig De Naeyer, Jeanine Uwera, Anita Asiimwe, Claire Gazille and Tony Reid

    Citation: BMC Pediatrics 2008 8:39

    Content type: Research article

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  2. Very low birthweight infants are at risk for deficits in cognitive and language development, as well as attention and behaviour problems. Maternal sensitive behaviour (i.e. awareness of infant cues and appropr...

    Authors: Phyllis Zelkowitz, Nancy Feeley, Ian Shrier, Robyn Stremler, Ruta Westreich, David Dunkley, Russell Steele, Zeev Rosberger, Francine Lefebvre and Apostolos Papageorgiou

    Citation: BMC Pediatrics 2008 8:38

    Content type: Study protocol

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  3. The diagnosis of infantile hypertrophic pyloric stenosis (IHPS), although traditionally clinical, is now increasingly dependent on radiological corroboration. The rate of negative exploration in IHPS has been ...

    Authors: Dhanya Mullassery, Sreelakshmi Mallappa, Raheel Shariff, Ross J Craigie, Paul D Losty, Simon E Kenny, David Pilling and Colin T Baillie

    Citation: BMC Pediatrics 2008 8:37

    Content type: Research article

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  4. Food allergy prevalence is increasing in US children. Presently, the primary means of preventing potentially fatal reactions are avoidance of allergens, prompt recognition of food allergy reactions, and knowle...

    Authors: Ruchi S Gupta, Jennifer S Kim, Julia A Barnathan, Laura B Amsden, Lakshmi S Tummala and Jane L Holl

    Citation: BMC Pediatrics 2008 8:36

    Content type: Research article

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  5. It is generally assumed that most patients with celiac disease (CD) have a slowed growth in terms of length (or height) and weight. However, the effectiveness of slowed growth as a tool for identifying childre...

    Authors: Paula van Dommelen, Floor K Grote, Wilma Oostdijk, Sabine MPF de Muinck Keizer-Schrama, Bart Boersma, Gerard M Damen, Cassandra G Csizmadia, Paul H Verkerk, Jan M Wit and Stef van Buuren

    Citation: BMC Pediatrics 2008 8:35

    Content type: Research article

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  6. Antiretroviral therapy (ART) dramatically improves outcomes for children in Africa; however excellent adherence is required for treatment success. This study describes the utility of different measures of adhe...

    Authors: Mary-Ann Davies, Andrew Boulle, Tanzeem Fakir, James Nuttall and Brian Eley

    Citation: BMC Pediatrics 2008 8:34

    Content type: Research article

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  7. Henoch Schonlein purpura (HSP) is a common vasculitis of small vessels whereas endothelin-1 (ET-1) is usually reported elevated in vasculities and systematic inflammation. The aim of the present study was to i...

    Authors: S Fessatou, P Nicolaidou, D Gourgiotis, H Georgouli, K Douros, M Moustaki and A Fretzayas

    Citation: BMC Pediatrics 2008 8:33

    Content type: Research article

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  8. Otitis media (OM) is the most common paediatric illness for which antibiotics are prescribed. In Australian Aboriginal children OM is frequently asymptomatic and starts at a younger age, is more common and mor...

    Authors: Deborah Lehmann, Sharon Weeks, Peter Jacoby, Dimity Elsbury, Janine Finucane, Annette Stokes, Ruth Monck and Harvey Coates

    Citation: BMC Pediatrics 2008 8:32

    Content type: Research article

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  9. Obesity is a one of the most common nutritional disorder worldwide, clearly associated with the metabolic syndrome, condition with implications for the development of many chronic diseases.

    Authors: Margoth Caceres, Carlos G Teran, Susana Rodriguez and Marcos Medina

    Citation: BMC Pediatrics 2008 8:31

    Content type: Research article

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  10. Assessment of 'potential intellectual ability' of children with severe intellectual disability (ID) is limited, as current tests designed for normal children do not maintain their interest. Thus a manual puzzle v...

    Authors: Katrina D Bello, Nahal Goharpey, Sheila G Crewther and David P Crewther

    Citation: BMC Pediatrics 2008 8:30

    Content type: Research article

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  11. Numerous short-statured children are evaluated for growth hormone (GH) deficiency (GHD). In most patients, GH provocative tests are normal and are thus in retrospect unnecessary.

    Authors: Laëtitia Duché, Christine Trivin, Wassim Chemaitilly, Jean Claude Souberbielle, Gérard Bréart, Raja Brauner and Martin Chalumeau

    Citation: BMC Pediatrics 2008 8:29

    Content type: Research article

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  12. It is sometimes difficult to distinguish between premature thelarche and precocious puberty in girls who develop breasts before the age of 8 years. We evaluated the frequencies of the signs associated with bre...

    Authors: Géraldine Prété, Ana-Claudia Couto-Silva, Christine Trivin and Raja Brauner

    Citation: BMC Pediatrics 2008 8:27

    Content type: Research article

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  13. Infants born at extreme prematurity are at high risk of developmental disability. A major risk factor for disability is having a low level of thyroid hormone described as hypothyroxinaemia, which is recognised...

    Authors: Sze M Ng, Mark A Turner, Carrol Gamble, Mohammed Didi, Suresh Victor, Christina Malamateniou, Laura M Parkes, Anna Tietze, Lloyd Gregory, Vanessa Sluming, Laurence Abernethy and Alan M Weindling

    Citation: BMC Pediatrics 2008 8:26

    Content type: Study protocol

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  14. To reduce the risk of brain damage children with acute lymphoblastic leukaemia (ALL) are nowadays mainly treated with intrathecal chemotherapy (ITC) instead of central nervous system (CNS) radiation therapy (C...

    Authors: Jaap Huisman, Eline J Aukema, Jan Berend Deijen, Silvia CCM van Coeverden, Gertjan JL Kaspers, Heleen JH van der Pal and Henriette A Delemarre-van de Waal

    Citation: BMC Pediatrics 2008 8:25

    Content type: Research article

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  15. Changes and relationships of components of the cytokine and IGF systems have been shown in placenta and cord serum of fetal growth restricted (FGR) compared with normal newborns (AGA). This study aimed to anal...

    Authors: Maria E Street, Enzo Grossi, Cecilia Volta, Elena Faleschini and Sergio Bernasconi

    Citation: BMC Pediatrics 2008 8:24

    Content type: Research article

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  16. For children at high risk of chronic suppurative otitis media (CSOM), strategies to prevent acute otitis media with perforation (AOMwiP) may reduce progression to CSOM.

    Authors: Amanda J Leach, Peter S Morris and John D Mathews

    Citation: BMC Pediatrics 2008 8:23

    Content type: Research article

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  17. Severe malnutrition in childhood associated with HIV infection presents a serious humanitarian and public health challenge in Southern Africa. The aim of this study was to collect country wide data on HIV infe...

    Authors: Susan Thurstans, Marko Kerac, Kenneth Maleta, Theresa Banda and Anne Nesbitt

    Citation: BMC Pediatrics 2008 8:22

    Content type: Research article

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  18. As abnormal growth might be the first manifestation of undetected diseases, it is important to have accurate referral criteria and a proper diagnostic work-up. In the present paper we evaluate the diagnostic w...

    Authors: Floor K Grote, Wilma Oostdijk, Sabine MPF De Muinck Keizer-Schrama, Paula van Dommelen, Stef van Buuren, Friedo W Dekker, Arnoldus G Ketel, Henriette A Moll and Jan M Wit

    Citation: BMC Pediatrics 2008 8:21

    Content type: Research article

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  19. Persistent arterial dysfunction in patients with a history of Kawasaki disease (KD) and an integral role of oxidative stress in the development of cardiovascular disease are increasingly recognized. We sought ...

    Authors: Yiu-fai Cheung, Karmin O, Connie WH Woo, Stephanie Armstrong, Yaw L Siow, Pak-cheong Chow and Eddie WY Cheung

    Citation: BMC Pediatrics 2008 8:20

    Content type: Research article

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  20. The child growth standards released by the World Health Organization (WHO) in 2006 have several technical advantages over the previous 1977 National Center for Health Statistics (NCHS)/WHO reference and are re...

    Authors: Hong Yang and Mercedes de Onis

    Citation: BMC Pediatrics 2008 8:19

    Content type: Research article

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  21. Procalcitonin (PCT) and C reactive protein (CRP) have been used as infection parameters. PCT increase correlates with the infection's severity, course, and mortality. Post-cardiocirculatory arrest syndrome may...

    Authors: Marta Los Arcos, Corsino Rey, Andrés Concha, Alberto Medina and Belen Prieto

    Citation: BMC Pediatrics 2008 8:18

    Content type: Research article

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  22. A hypoxic-ischaemic insult occurring around the time of birth may result in an encephalopathic state characterised by the need for resuscitation at birth, neurological depression, seizures and electroencephalo...

    Authors: Dennis Azzopardi, Peter Brocklehurst, David Edwards, Henry Halliday, Malcolm Levene, Marianne Thoresen and Andrew Whitelaw

    Citation: BMC Pediatrics 2008 8:17

    Content type: Study protocol

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  23. In Nepal, more than 90% of the deliveries take place at home where birth weight is often not recorded. In developing countries, low birth weight (LBW, <2500 grams) accounts for 60–80% of neonatal deaths. Early...

    Authors: Chandrashekhar T Sreeramareddy, Neena Chuni, Rajkumar Patil, Dela Singh and Brishna Shakya

    Citation: BMC Pediatrics 2008 8:16

    Content type: Research article

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  24. Little is known about how pediatricians or internists manage influenza symptoms. Recent guidelines on antiviral prescribing by the Centers for Disease Control and Prevention (CDC) make almost no distinction be...

    Authors: Michael B Rothberg, Aleta B Bonner, MH Rajab, Barbara W Stechenberg and David N Rose

    Citation: BMC Pediatrics 2008 8:15

    Content type: Research article

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  25. Skin-to-skin contact, or kangaroo mother care (KMC) has been shown to be efficacious in diminishing pain response to heel lance in full term and moderately preterm neonates. The purpose of this study was to de...

    Authors: C Celeste Johnston, Francoise Filion, Marsha Campbell-Yeo, Celine Goulet, Linda Bell, Kathryn McNaughton, Jasmine Byron, Marilyn Aita, G Allen Finley and Claire-Dominique Walker

    Citation: BMC Pediatrics 2008 8:13

    Content type: Research article

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  26. Early diagnosis and intervention for children with Fetal Alcohol Spectrum Disorder (FASD) reduces the risk of developing a range of secondary social, emotional and behavioural problems and provides an opportun...

    Authors: Elizabeth Peadon, Emily Fremantle, Carol Bower and Elizabeth J Elliott

    Citation: BMC Pediatrics 2008 8:12

    Content type: Research article

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  27. Gastroesophageal reflux is a common diagnosis in infants. Yet, there is no information on the demographics of those hospitalized with reflux. The aim of this study is to describe the demographics of children w...

    Authors: Susan S Baker, Christine M Roach, Michael S Leonard and Robert D Baker

    Citation: BMC Pediatrics 2008 8:11

    Content type: Research article

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  28. Obesity is now a global epidemic. In this study, we aimed to assess the rates of obesity using several major diagnostic criteria in Chinese school adolescents in Hong Kong.

    Authors: Gary TC Ko, Risa Ozaki, Gary WK Wong, Alice PS Kong, Wing-Yee So, Peter CY Tong, Michael HM Chan, Chung-Shun Ho, Christopher WK Lam and Juliana CN Chan

    Citation: BMC Pediatrics 2008 8:10

    Content type: Research article

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  29. Weight screening in schools has been proposed as one strategy to address childhood obesity. Students' response to such screening is unexplored, however. In this study we evaluated the perceived comfort, utilit...

    Authors: Karrie A Kalich, Virginia Chomitz, Karen E Peterson, Robert McGowan, Robert F Houser and Aviva Must

    Citation: BMC Pediatrics 2008 8:9

    Content type: Research article

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  30. Leukemia is the most common childhood cancer. With the exception of Down syndrome, prenatal radiation exposure, and higher birth weight, particularly for acute lymphoid leukemia (ALL), few risk factors have be...

    Authors: Kimberly J Johnson, John T Soler, Susan E Puumala, Julie A Ross and Logan G Spector

    Citation: BMC Pediatrics 2008 8:7

    Content type: Research article

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  31. HIV is a leading cause of morbidity and mortality in Zambia. Like many other African nations with high HIV burden, heterosexual intercourse is the commonest mode of HIV spread. The estimation of prevalence and...

    Authors: Seter Siziya, Adamson S Muula, Lawrence N Kazembe and Emmanuel Rudatsikira

    Citation: BMC Pediatrics 2008 8:6

    Content type: Research article

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  32. Acute seizures are a common cause of paediatric admissions to hospitals in resource poor countries and a risk factor for neurological and cognitive impairment and epilepsy. We determined the incidence, aetiolo...

    Authors: Richard Idro, Samson Gwer, Michael Kahindi, Hellen Gatakaa, Tony Kazungu, Moses Ndiritu, Kathryn Maitland, Brian GR Neville, Piet A Kager and Charles RJC Newton

    Citation: BMC Pediatrics 2008 8:5

    Content type: Research article

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  33. Anorexia Nervosa (AN) is a serious, debilitating condition that causes significant physical, emotional, and functional impairment. The condition is characterized by destructive weight loss behaviours and a ref...

    Authors: Wendy Spettigue, Annick Buchholz, Katherine Henderson, Stephen Feder, David Moher, Kader Kourad, Isabelle Gaboury, Mark Norris and Sheila Ledoux

    Citation: BMC Pediatrics 2008 8:4

    Content type: Study protocol

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  34. To promote participation by parents in the care of their child in neonatal intensive care units (NICU), health professionals need better understanding of what facilitates and what obstructs participation. The ...

    Authors: Helena Wigert, Anna-Lena Hellström and Marie Berg

    Citation: BMC Pediatrics 2008 8:3

    Content type: Research article

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  35. Recurrent pain is a common complaint among adolescents. Children learn to resolve or cope with pain largely through family dynamics, particularly maternal influences. By adolescence, young people possess an ar...

    Authors: Jill E Hatchette, Patrick J McGrath, Michael Murray and G Allen Finley

    Citation: BMC Pediatrics 2008 8:2

    Content type: Research article

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  36. The tuberculosis (TB) and human immunodeficiency virus (HIV) epidemics are poorly controlled in sub-Saharan Africa, where highly active antiretroviral treatment (HAART) has become more freely available. Little...

    Authors: Elisabetta Walters, Mark F Cotton, Helena Rabie, H Simon Schaaf, Lourens O Walters and Ben J Marais

    Citation: BMC Pediatrics 2008 8:1

    Content type: Research article

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  37. The aim of this study was to investigate the prevalence of cerebral palsy (CP) as well as to characterize the CP population, its participation in a secondary prevention programme (CPUP) and to validate the CPU...

    Authors: Lena Westbom, Gunnar Hagglund and Eva Nordmark

    Citation: BMC Pediatrics 2007 7:41

    Content type: Research article

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  38. Many definitions are being used to conceptualize child health problems. With survey data, commonly used indicators for identifying children with health problems have included chronic condition checklists, meas...

    Authors: Dafna E Kohen, Jamie C Brehaut, Rochelle E Garner, Anton R Miller, Lucyna M Lach, Anne F Klassen and Peter L Rosenbaum

    Citation: BMC Pediatrics 2007 7:40

    Content type: Research article

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  39. The purpose of this study was to characterize total homocysteine (tHcy) levels at birth in preterm and term infants and identify associations with intraventricular hemorrhage (IVH) and other neonatal outcomes ...

    Authors: Wendy J Sturtz, Kathleen H Leef, Amy B Mackley, Shailja Sharma, Teodoro Bottiglieri and David A Paul

    Citation: BMC Pediatrics 2007 7:38

    Content type: Research article

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  40. Recently, hyperbaric oxygen therapy (HBOT) has increased in popularity as a treatment for autism. Numerous studies document oxidative stress and inflammation in individuals with autism; both of these condition...

    Authors: Daniel A Rossignol, Lanier W Rossignol, S Jill James, Stepan Melnyk and Elizabeth Mumper

    Citation: BMC Pediatrics 2007 7:36

    Content type: Research article

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  41. Guidelines in paediatric oncology encourage health care providers to share relevant information with young patients and parents to enable their active participation in decision making. It is not clear to what ...

    Authors: Marieke Zwaanswijk, Kiek Tates, Sandra van Dulmen, Peter M Hoogerbrugge, Willem A Kamps and Jozien M Bensing

    Citation: BMC Pediatrics 2007 7:35

    Content type: Research article

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  42. Although recent studies suggest that there is an association between intimate partner violence and child mortality, the underlying mechanisms are still unknown. It is against this background that as a secondar...

    Authors: Charles AS Karamagi, James K Tumwine, Thorkild Tylleskar and Kristian Heggenhougen

    Citation: BMC Pediatrics 2007 7:34

    Content type: Research article

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  43. The epidemic of obesity is increasing in all countries. However, the number of controlled studies focusing on childhood obesity, with a long follow-up is still limited. Even though Behavioral Therapy shows som...

    Authors: Rita Tanas, Renzo Marcolongo, Stefania Pedretti and Giuseppe Gilli

    Citation: BMC Pediatrics 2007 7:33

    Content type: Research article

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  44. In 2006, a new rotavirus vaccine (RotaTeq) was licensed in the US and recommended for routine immunization of all US infants. Because a previously licensed vaccine (Rotashield) was withdrawn from the US for sa...

    Authors: Manish M Patel, Alan P Janssen, Richard R Tardif, Mark Herring and Umesh D Parashar

    Citation: BMC Pediatrics 2007 7:32

    Content type: Research article

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