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  1. Anorexia Nervosa (AN) is a serious, debilitating condition that causes significant physical, emotional, and functional impairment. The condition is characterized by destructive weight loss behaviours and a ref...

    Authors: Wendy Spettigue, Annick Buchholz, Katherine Henderson, Stephen Feder, David Moher, Kader Kourad, Isabelle Gaboury, Mark Norris and Sheila Ledoux

    Citation: BMC Pediatrics 2008 8:4

    Content type: Study protocol

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  2. To promote participation by parents in the care of their child in neonatal intensive care units (NICU), health professionals need better understanding of what facilitates and what obstructs participation. The ...

    Authors: Helena Wigert, Anna-Lena Hellström and Marie Berg

    Citation: BMC Pediatrics 2008 8:3

    Content type: Research article

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  3. Recurrent pain is a common complaint among adolescents. Children learn to resolve or cope with pain largely through family dynamics, particularly maternal influences. By adolescence, young people possess an ar...

    Authors: Jill E Hatchette, Patrick J McGrath, Michael Murray and G Allen Finley

    Citation: BMC Pediatrics 2008 8:2

    Content type: Research article

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  4. The tuberculosis (TB) and human immunodeficiency virus (HIV) epidemics are poorly controlled in sub-Saharan Africa, where highly active antiretroviral treatment (HAART) has become more freely available. Little...

    Authors: Elisabetta Walters, Mark F Cotton, Helena Rabie, H Simon Schaaf, Lourens O Walters and Ben J Marais

    Citation: BMC Pediatrics 2008 8:1

    Content type: Research article

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  5. The aim of this study was to investigate the prevalence of cerebral palsy (CP) as well as to characterize the CP population, its participation in a secondary prevention programme (CPUP) and to validate the CPU...

    Authors: Lena Westbom, Gunnar Hagglund and Eva Nordmark

    Citation: BMC Pediatrics 2007 7:41

    Content type: Research article

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  6. Many definitions are being used to conceptualize child health problems. With survey data, commonly used indicators for identifying children with health problems have included chronic condition checklists, meas...

    Authors: Dafna E Kohen, Jamie C Brehaut, Rochelle E Garner, Anton R Miller, Lucyna M Lach, Anne F Klassen and Peter L Rosenbaum

    Citation: BMC Pediatrics 2007 7:40

    Content type: Research article

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  7. The purpose of this study was to characterize total homocysteine (tHcy) levels at birth in preterm and term infants and identify associations with intraventricular hemorrhage (IVH) and other neonatal outcomes ...

    Authors: Wendy J Sturtz, Kathleen H Leef, Amy B Mackley, Shailja Sharma, Teodoro Bottiglieri and David A Paul

    Citation: BMC Pediatrics 2007 7:38

    Content type: Research article

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  8. Recently, hyperbaric oxygen therapy (HBOT) has increased in popularity as a treatment for autism. Numerous studies document oxidative stress and inflammation in individuals with autism; both of these condition...

    Authors: Daniel A Rossignol, Lanier W Rossignol, S Jill James, Stepan Melnyk and Elizabeth Mumper

    Citation: BMC Pediatrics 2007 7:36

    Content type: Research article

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  9. Guidelines in paediatric oncology encourage health care providers to share relevant information with young patients and parents to enable their active participation in decision making. It is not clear to what ...

    Authors: Marieke Zwaanswijk, Kiek Tates, Sandra van Dulmen, Peter M Hoogerbrugge, Willem A Kamps and Jozien M Bensing

    Citation: BMC Pediatrics 2007 7:35

    Content type: Research article

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  10. Although recent studies suggest that there is an association between intimate partner violence and child mortality, the underlying mechanisms are still unknown. It is against this background that as a secondar...

    Authors: Charles AS Karamagi, James K Tumwine, Thorkild Tylleskar and Kristian Heggenhougen

    Citation: BMC Pediatrics 2007 7:34

    Content type: Research article

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  11. The epidemic of obesity is increasing in all countries. However, the number of controlled studies focusing on childhood obesity, with a long follow-up is still limited. Even though Behavioral Therapy shows som...

    Authors: Rita Tanas, Renzo Marcolongo, Stefania Pedretti and Giuseppe Gilli

    Citation: BMC Pediatrics 2007 7:33

    Content type: Research article

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  12. In 2006, a new rotavirus vaccine (RotaTeq) was licensed in the US and recommended for routine immunization of all US infants. Because a previously licensed vaccine (Rotashield) was withdrawn from the US for sa...

    Authors: Manish M Patel, Alan P Janssen, Richard R Tardif, Mark Herring and Umesh D Parashar

    Citation: BMC Pediatrics 2007 7:32

    Content type: Research article

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  13. Children with cerebral palsy receive a variety of long-term physical and occupational therapy interventions to facilitate development and to enhance functional independence in movement, self-care, play, school...

    Authors: Mary Law, Johanna Darrah, Nancy Pollock, Peter Rosenbaum, Dianne Russell, Stephen D Walter, Theresa Petrenchik, Brenda Wilson and Virginia Wright

    Citation: BMC Pediatrics 2007 7:31

    Content type: Study protocol

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  14. Studies in adult intensive care have highlighted the importance of insulin and improved glucose control on survival, with 32% reduction in mortality, 22% reduction in intensive care stay and halving of the inc...

    Authors: Kathryn Beardsall, Sophie Vanhaesebrouck, Amanda L Ogilvy-Stuart, Jag S Ahluwalia, Christine Vanhole, Christopher Palmer, Paula Midgley, Mike Thompson, Luc Cornette, Mirjam Weissenbruch, Marta Thio, Francis de Zegher and David Dunger

    Citation: BMC Pediatrics 2007 7:29

    Content type: Study protocol

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  15. Beginning with the 2004–05 influenza season, the Advisory Committee on Immunization Practices (ACIP) strengthened their existing encouragement that children aged 6–23 months receive influenza vaccination by cr...

    Authors: Laura A Zimmerman, Diana L Bartlett, Kyle S Enger, Kimiko Gosney and Warren G Williams

    Citation: BMC Pediatrics 2007 7:28

    Content type: Research article

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  16. Although sucrose has been accepted as an effective analgesic agent for procedural pain in neonates, previous studies are largely in the NICU population using the procedure of heel lance. This is the first repo...

    Authors: Sarah J Curtis, Hsing Jou, Samina Ali, Ben Vandermeer and Terry Klassen

    Citation: BMC Pediatrics 2007 7:27

    Content type: Research article

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  17. The trial aims to evaluate whether neonatal mortality can be reduced through systemic changes to the provision and promotion of healthcare. Neonatal mortality rates in India are high compared to other low inco...

    Authors: Peter Boone, Vera Mann, Alexander Eble, Tarana Mendiratta, Rohini Mukherjee, Ryan Figueiredo, Chitra Jayanty, Chris Frost, M Reddy Padmanabh and Diana Elbourne

    Citation: BMC Pediatrics 2007 7:26

    Content type: Study protocol

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  18. Progressive encephalopathy (PE) in children is a heterogeneous group of diseases mainly composed of metabolic diseases, but it consists also of neurodegenerative disorders where neither metabolic nor other cau...

    Authors: Petter Stromme, Oivind Juris Kanavin, Michael Abdelnoor, Berit Woldseth, Terje Rootwelt, Jorgen Diderichsen, Bjorn Bjurulf, Finn Sommer and Per Magnus

    Citation: BMC Pediatrics 2007 7:25

    Content type: Research article

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  19. More than 90% of heart murmurs in children are innocent. Frequently the skills of the first examiner are not adequate to differentiate between innocent and pathological murmurs. Our goal was to evaluate the va...

    Authors: Anna-Leena Noponen, Sakari Lukkarinen, Anna Angerla and Raimo Sepponen

    Citation: BMC Pediatrics 2007 7:23

    Content type: Research article

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  20. We evaluated the use of computerized quantification of wheezing and crackles compared to a clinical score in assessing the effect of inhaled albuterol or inhaled epinephrine in infants with RSV bronchiolitis.

    Authors: Raphael Beck, Nael Elias, Shay Shoval, Naveh Tov, Gil Talmon, Simon Godfrey and Lea Bentur

    Citation: BMC Pediatrics 2007 7:22

    Content type: Technical advance

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  21. It is important to determine if rates of survival and major neurodevelopmental impairment in extremely low gestational age newborns (ELGANs; infants born at 23–27 weeks gestation) are changing over time.

    Authors: Lisa K Washburn, Robert G Dillard, Donald J Goldstein, Kurt L Klinepeter, Raye-Ann deRegnier and Thomas Michael O'Shea

    Citation: BMC Pediatrics 2007 7:20

    Content type: Research article

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  22. Increasing activity levels in adolescents with obesity requires the development of exercise programs that are both attractive to adolescents and easily reproducible. The aim of this study was to develop a modu...

    Authors: Peter HC Klijn, Olga H van der Baan-Slootweg and Henk F van Stel

    Citation: BMC Pediatrics 2007 7:19

    Content type: Research article

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  23. Mild gestational diabetes is a common complication of pregnancy, affecting up to 9% of pregnant women. Treatment of mild GDM is known to reduce adverse perinatal outcomes such as macrosomia and associated birt...

    Authors: Louise K Pirc, Julie A Owens, Caroline A Crowther, Kristyn Willson, Miles J De Blasio and Jeffrey S Robinson

    Citation: BMC Pediatrics 2007 7:18

    Content type: Research article

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  24. Many studies in sub-Saharan Africa have occasionally reported a higher prevalence of stunting in male children compared to female children. This study examined whether there are systematic sex differences in s...

    Authors: Henry Wamani, Anne Nordrehaug Åstrøm, Stefan Peterson, James K Tumwine and Thorkild Tylleskär

    Citation: BMC Pediatrics 2007 7:17

    Content type: Research article

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  25. In the past, effortful exercises were considered inappropriate for children with spastic cerebral palsy (CP) due to concern that they would escalate abnormalities including spasticity and abnormal movement pat...

    Authors: Eileen G Fowler, Loretta M Knutson, Sharon K DeMuth, Mia Sugi, Kara Siebert, Victoria Simms, Stanley P Azen and Carolee J Winstein

    Citation: BMC Pediatrics 2007 7:14

    Content type: Study protocol

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  26. Few studies address the use of paediatric highly active antiretroviral therapy (HAART) in Africa.

    Authors: Anand Reddi, Sarah C Leeper, Anneke C Grobler, Rosemary Geddes, K Holly France, Gillian L Dorse, Willem J Vlok, Mbali Mntambo, Monty Thomas, Kristy Nixon, Helga L Holst, Quarraisha Abdool Karim, Nigel C Rollins, Hoosen M Coovadia and Janet Giddy

    Citation: BMC Pediatrics 2007 7:13

    Content type: Research article

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  27. Delivery of tobramycin by inhalation to the lungs of patients with cystic fibrosis (CF) who are infected with Pseudomonas aeruginosa has been proven to be effective and safe. The aerosol administration allows hig...

    Authors: Roberto P Santos, Emad Awa and Ran D Anbar

    Citation: BMC Pediatrics 2007 7:11

    Content type: Case report

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  28. Exclusive breastfeeding is recommended as the best feeding alternative for infants up to six months and has a protective effect against mortality and morbidity. It also seems to lower HIV-1 transmission compar...

    Authors: Ingunn Marie S Engebretsen, Henry Wamani, Charles Karamagi, Nulu Semiyaga, James Tumwine and Thorkild Tylleskär

    Citation: BMC Pediatrics 2007 7:10

    Content type: Research article

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  29. The results of recent studies suggest the usefulness of PCT for early diagnosis of neonatal sepsis, with varying results. The aim of this prospective multicenter study was to determine the behavior of serum PC...

    Authors: José B López Sastre, David Pérez Solís, Vicente Roqués Serradilla, Belén Fernández Colomer and Gil D Coto Cotallo

    Citation: BMC Pediatrics 2007 7:9

    Content type: Research article

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  30. Factor V deficiency is a rare autosomal recessive coagulation disorder. Awareness of presenting features and management is important to avoid bleeding complications associated with mortality and neurodisability.

    Authors: Amol Chingale, Michael Eisenhut, Anjali Gadiraju and Ri Liesner

    Citation: BMC Pediatrics 2007 7:8

    Content type: Case report

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  31. Procedural pain relief is sub-optimal in neonates. Topical tetracaine provides pain relief in children. Evidence of its efficacy and safety in neonates is limited. The objective of this study was to assess the...

    Authors: Brigitte Lemyre, Debora L Hogan, Isabelle Gaboury, Rebecca Sherlock, Colline Blanchard and David Moher

    Citation: BMC Pediatrics 2007 7:7

    Content type: Research article

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  32. Brachmann de Lange syndrome (BDLS) is a multiple congenital anomaly syndrome characterized by a distinctive facial appearance, prenatal and postnatal growth deficiency, psychomotor delay, behavioral problems, ...

    Authors: Mona Ellaithi, David Gisselsson, Therese Nilsson, Atif Elagib, Imad Fadl-Elmula and Mashair Abdelgadir

    Citation: BMC Pediatrics 2007 7:6

    Content type: Case report

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  33. A standard contrast enema for Hirschsprung's disease can sometimes be inconclusive in delineating a transition zone especially in neonates and infants. The aim of this study was to determine the utility and di...

    Authors: Akshay Pratap, Devendra K Gupta, Awadhesh Tiwari, Arvind K Sinha, Nisha Bhatta, Satyendra N Singh, Chandra S Agrawal, Anand Kumar and Shailesh Adhikary

    Citation: BMC Pediatrics 2007 7:5

    Content type: Research article

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  34. Hypophosphatasia (HP) is characterized by a genetic defect in the tissue-nonspecific alkaline phosphatase (TNSALP) gene and predominantly an autosomal recessive trait. HP patients suffer from reduced bone mine...

    Authors: Hermann J Girschick, Etienne Mornet, Meinrad Beer, Monika Warmuth-Metz and Peter Schneider

    Citation: BMC Pediatrics 2007 7:3

    Content type: Case report

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  35. Documentation of superfoetation is extremely rare in humans., The younger foetus has invariably been small for gestational age (estimated from the date of the last menstrual bleed) in all the cases reported in...

    Authors: Noopur Baijal, Mohit Sahni, Neeraj Verma, Amit Kumar, Nittin Parkhe and Jacob M Puliyel

    Citation: BMC Pediatrics 2007 7:2

    Content type: Case report

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  36. Implementation of health research findings is important for medicine to be evidence-based. Previous studies have found variation in the information sources thought to be of greatest importance to clinicians bu...

    Authors: Teresa H Jones, Steve Hanney and Martin J Buxton

    Citation: BMC Pediatrics 2007 7:1

    Content type: Research article

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  37. Researchers and clinicians are seeking to develop efficacious behavioral interventions to treat overweight children; however, few studies have documented the behavioral correlates of overweight children in com...

    Authors: Shelagh A Mulvaney, Kristine L Kaemingk, James L Goodwin and Stuart F Quan

    Citation: BMC Pediatrics 2006 6:34

    Content type: Research article

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  38. The purpose of this study was to determine the prevalence of high blood pressure (HBP) and associated risk factors in school children 8 to 13 years of age.

    Authors: Ximena Urrutia-Rojas, Christie U Egbuchunam, Sejong Bae, John Menchaca, Manuel Bayona, Patrick A Rivers and Karan P Singh

    Citation: BMC Pediatrics 2006 6:32

    Content type: Research article

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  39. In 1999, the American Academy of Pediatrics and U.S. Public Health Service recommended suspending the birth dose of hepatitis B vaccine due to concerns about potential mercury exposure. A previous report found...

    Authors: Nancy D Lin, Ken Kleinman, K Arnold Chan, Xian-Jie Yu, Eric K France, Feifei Wei, John P Mullooly, Steven Black, David K Shay, Margarette Kolczak and Tracy A Lieu

    Citation: BMC Pediatrics 2006 6:31

    Content type: Research article

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  40. Childhood injury is the leading cause of mortality, morbidity and permanent disability in children in the developed world. This research examines relationships between socio-economic status (SES), demographics...

    Authors: Susan J Gilbride, Cameron Wild, Douglas R Wilson, Lawrence W Svenson and Donald W Spady

    Citation: BMC Pediatrics 2006 6:30

    Content type: Research article

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