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  1. Nosocomial Infections (NI) are a frequent and relevant problem. The purpose of this study was to determine the epidemiology of the three most common NI in a Pediatric Intensive Care Unit from a developing coun...

    Authors: María R Becerra, José A Tantaleán, Víctor J Suárez, Margarita C Alvarado, Jorge L Candela and Flor C Urcia

    Citation: BMC Pediatrics 2010 10:66

    Content type: Research article

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  2. This study aimed to profile levels of blood cells and serum cytokines during afebrile and febrile phases of periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome to advance pathophysiolog...

    Authors: Kelly L Brown, Per Wekell, Veronica Osla, Martina Sundqvist, Karin Sävman, Anders Fasth, Anna Karlsson and Stefan Berg

    Citation: BMC Pediatrics 2010 10:65

    Content type: Research article

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  3. Stories may be an effective tool to communicate with and influence patients because of their ability to engage the reader. The objective of this paper is to describe the development of a story-based interventi...

    Authors: Lisa Hartling, Shannon Scott, Rena Pandya, David Johnson, Ted Bishop and Terry P Klassen

    Citation: BMC Pediatrics 2010 10:64

    Content type: Research article

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  4. Infant formulas are sophisticated milk-based feeds for infants which are used as a substitute for breast milk. Historically they are known to be contaminated by aluminium and in the past this has raised health...

    Authors: Shelle-Ann M Burrell and Christopher Exley

    Citation: BMC Pediatrics 2010 10:63

    Content type: Research article

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  5. Surveys in Vietnam have indicated that wasting and stunting have been prevalent among children, but the country is undergoing rapid socio-economic changes and little has been known about the relative situation...

    Authors: Arild Vaktskjold, Đoàn Văn Trí, Dương Trọng Phỉ and Torkjel Sandanger

    Citation: BMC Pediatrics 2010 10:62

    Content type: Research article

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  6. Earlier studies have shown an association between secondhand tobacco smoke and allergy development in children. Furthermore, there is an increased risk of developing an allergy if the parents have an allergy. ...

    Authors: Kristina Hansen, Elisabeth Mangrio, Martin Lindström and Maria Rosvall

    Citation: BMC Pediatrics 2010 10:61

    Content type: Research article

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  7. Menarcheal age is a sensitive indicator of environmental conditions during childhood. The aim of study is to determine the age at menarche and growth status in adolescents in a rural area of Tarka, Wannune, Ni...

    Authors: Daniel T Goon, Abel L Toriola, Jonathan Uever, Sarah Wuam and Olutoyin M Toriola

    Citation: BMC Pediatrics 2010 10:60

    Content type: Research article

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  8. One of the most serious, yet common co-morbidities of obesity is insulin resistance, which if untreated may progress to type 2 diabetes. This paper describes the insulin and glucose concentration distributions...

    Authors: Elizabeth Denney-Wilson, Christopher T Cowell, Anthony D Okely, Louise L Hardy, Robert Aitken and Timothy Dobbins

    Citation: BMC Pediatrics 2010 10:58

    Content type: Research article

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  9. Changing epidemiology and diagnostic difficulties of paediatric tuberculosis (TB) are being increasingly reported. Our aim was to describe clinico-epidemiological profile and diagnostic procedures used for pae...

    Authors: Chandrashekhar T Sreeramareddy, Narayan Ramakrishnareddy, Ravi K Shah, Ramkaji Baniya and Pradipta K Swain

    Citation: BMC Pediatrics 2010 10:57

    Content type: Research article

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  10. Scale up of paediatric antiretroviral therapy in resource limited settings continues despite limited access to routine laboratory monitoring. We documented the weight and height responses in HIV infected Ugand...

    Authors: Philippa M Musoke, Peter Mudiope, Linda N Barlow-Mosha, Patrick Ajuna, Danstan Bagenda, Michael M Mubiru, Thorkild Tylleskar and Mary G Fowler

    Citation: BMC Pediatrics 2010 10:56

    Content type: Research article

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  11. "Use it or lose it" is a well known saying which is applicable to boys with Duchenne Muscular Dystrophy (DMD). Besides the direct effects of the muscular dystrophy, the increasing effort to perform activities,...

    Authors: Merel Jansen, Imelda JM de Groot, Nens van Alfen and Alexander CH Geurts

    Citation: BMC Pediatrics 2010 10:55

    Content type: Study protocol

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  12. Since 2003 pediatric antiretroviral treatment (ART) programs have scaled-up in sub-Saharan Africa and should be evaluated to assess progress and identify areas for improvement. We evaluated secular trends in t...

    Authors: Catherine G Sutcliffe, Carolyn Bolton-Moore, Janneke H van Dijk, Matt Cotham, Bushimbwa Tambatamba and William J Moss

    Citation: BMC Pediatrics 2010 10:54

    Content type: Research article

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  13. Neonatal sepsis is difficult to diagnose and pathogens cannot be detected from blood cultures in many cases. Development of a rapid and accurate method for detecting pathogens is thus essential. The main purpo...

    Authors: Makoto Fujimori, Ken Hisata, Satoru Nagata, Nobuaki Matsunaga, Mitsutaka Komatsu, Hiromichi Shoji, Hiroaki Sato, Yuichiro Yamashiro, Takashi Asahara, Koji Nomoto and Toshiaki Shimizu

    Citation: BMC Pediatrics 2010 10:53

    Content type: Research article

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  14. Hyperglycemia in premature infants is associated with increased morbidity and mortality, but data on long-term outcome are limited. We investigated the effects of neonatal hyperglycemia (blood glucose ≥ 10 mmo...

    Authors: N Margreth van der Lugt, Vivianne EHJ Smits-Wintjens, Paul HT van Zwieten and Frans J Walther

    Citation: BMC Pediatrics 2010 10:52

    Content type: Research article

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  15. Many children with type 1 diabetes have poor glycaemic control. Since the Diabetes Control and Complications Trial (DCCT) showed that tighter control reduces complication rates, there has been more emphasis on...

    Authors: Katharine Barnard, Sian Thomas, Pamela Royle, Kathryn Noyes and Norman Waugh

    Citation: BMC Pediatrics 2010 10:50

    Content type: Research article

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  16. Some evidence suggests that obesity and behavior problems are related in children, but studies have been conflicting and have rarely included children under age 4. An association between behavior problems in e...

    Authors: Sarah E Anderson, Xin He, Sarah Schoppe-Sullivan and Aviva Must

    Citation: BMC Pediatrics 2010 10:49

    Content type: Research article

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  17. M. pneumoniae pneumonia (MP) has been reported in 10-40% of community-acquired pneumonia cases. We aimed to evaluate the difference of clinical features in children with MP, according to their age and chest radi...

    Authors: You-Sook Youn, Kyung-Yil Lee, Ja-Young Hwang, Jung-Woo Rhim, Jin-Han Kang, Joon-Sung Lee and Ji-Chang Kim

    Citation: BMC Pediatrics 2010 10:48

    Content type: Research article

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  18. We present a case of Xanthogranulomatous pyelonephritis (XGPN) in a male child with renal vein thrombus extending into the inferior vena cava. This is a rare presentation. XGPN is a rare type of renal infectio...

    Authors: Geetanjali Gupta, Reecha Singh, Dhananjay S Kotasthane, Vaishali D Kotasthane and Shailesh Kumar

    Citation: BMC Pediatrics 2010 10:47

    Content type: Case report

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  19. There are at least 51 adenovirus serotypes (AdV) known to cause human infections. The prevalence of the different human AdV (HAdV) serotypes varies among different regions. Presently, there are no reports of t...

    Authors: Juraina Abd-Jamil, Boon-Teong Teoh, Eddy H Hassan, Nuruliza Roslan and Sazaly AbuBakar

    Citation: BMC Pediatrics 2010 10:46

    Content type: Research article

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  20. Pediatric asthma is a serious public health problem in Chicago and has been designated a high priority concern by residents of Chicago's Humboldt Park, a diverse community area with a large number of Puerto Ri...

    Authors: Ruchi S Gupta, Juana Ballesteros, Elizabeth E Springston, Bridget Smith, Molly Martin, Eileen Wang and Maureen Damitz

    Citation: BMC Pediatrics 2010 10:45

    Content type: Research article

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  21. In Tanzania, less than a third of HIV infected children estimated to be in need of antiretroviral therapy (ART) are receiving it. In this setting where other infections and malnutrition mimic signs and symptom...

    Authors: Harriet Nuwagaba-Biribonwoha, Bazghina Werq-Semo, Aziz Abdallah, Amy Cunningham, John G Gamaliel, Sevestine Mtunga, Victoria Nankabirwa, Isaya Malisa, Luis F Gonzalez, Charles Massambu, Denis Nash, Jessica Justman and Elaine J Abrams

    Citation: BMC Pediatrics 2010 10:44

    Content type: Research article

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  22. Complementary feeding is currently recommended after six months of age, when the nutrients in breast milk alone are no longer adequate to support growth. Few studies have examined macro- and micro-nutrient int...

    Authors: James K Friel, Rhona M Hanning, Corinne A Isaak, Daniel Prowse and Angela C Miller

    Citation: BMC Pediatrics 2010 10:43

    Content type: Research article

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  23. The Rotavirus Efficacy and Safety Trial was a placebo-controlled Phase III study that evaluated the safety and efficacy of a three-dose pentavalent rotavirus vaccine (RV5) including its effect on healthcare ut...

    Authors: Robbin Itzler, Gary Koch, David O Matson, Leif Gothefors, Pierre Van Damme, Mark J DiNubile and Penny M Heaton

    Citation: BMC Pediatrics 2010 10:42

    Content type: Research article

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  24. Acid suppression with a proton pump inhibitor is standard treatment for gastroesophageal reflux disease and erosive esophagitis in adults and increasingly is becoming first-line therapy for children aged 1-17 ...

    Authors: Vasundhara Tolia, Nader N Youssef, Mark A Gilger, Barry Traxler and Marta Illueca

    Citation: BMC Pediatrics 2010 10:41

    Content type: Research article

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  25. Neonatal sepsis is a significant cause of morbidity and mortality in neonates. Appropriate clinical diagnosis and empirical treatment in a given setting is crucial as pathogens of bacterial sepsis and antibiot...

    Authors: Neema Kayange, Erasmus Kamugisha, Damas L Mwizamholya, Seni Jeremiah and Stephen E Mshana

    Citation: BMC Pediatrics 2010 10:39

    Content type: Research article

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  26. Respiratory syncytial virus (RSV) is an important pathogen causing annual epidemics of bronchiolitis and pneumonia among infants worldwide. High-risk infants currently receive RSV prophylaxis with palivizumab,...

    Authors: Pilar Fernández, Adrian Trenholme, Katia Abarca, M Pamela Griffin, Micki Hultquist, Brian Harris and Genevieve A Losonsky

    Citation: BMC Pediatrics 2010 10:38

    Content type: Research article

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  27. Bronchiolitis is the most common reason for admission of infants to hospital in developed countries. Fluid replacement therapy is required in about 30% of children admitted with bronchiolitis. There are curren...

    Authors: Ed Oakley, Franz E Babl, Jason Acworth, Meredith Borland, David Kreiser, Jocelyn Neutze, Theane Theophilos, Susan Donath, Mike South and Andrew Davidson

    Citation: BMC Pediatrics 2010 10:37

    Content type: Study protocol

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  28. Worldwide, insulin-dependent type 1 diabetes is one of the most frequently diagnosed long-term endocrine disorders found in children and the incidences of this diseased is still increasing. In Sweden the routi...

    Authors: Lisbeth Jönsson, Inger Hallström and Anita Lundqvist

    Citation: BMC Pediatrics 2010 10:36

    Content type: Research article

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  29. Over the past few years, great efforts have been made to screen duct-dependent congenital heart diseases in the newborn. Arterial pulse oximetry screening (foot and/or right hand) has been put forth as the mos...

    Authors: Christoph Rüegger, Hans Ulrich Bucher and Romaine Arlettaz Mieth

    Citation: BMC Pediatrics 2010 10:35

    Content type: Research article

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  30. Systematic reviews (SRs) are considered an important tool for decision-making. There has been no recent comprehensive identification or description of child-relevant SRs. A description of existing child-releva...

    Authors: Simon Bow, Jeffrey Klassen, Annabritt Chisholm, Lisa Tjosvold, Denise Thomson, Terry P Klassen, David Moher and Lisa Hartling

    Citation: BMC Pediatrics 2010 10:34

    Content type: Research article

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  31. Among children, early mortality following highly active antiretroviral therapy (HAART) remains high. It is important to define correlates of mortality in order to improve outcome.

    Authors: Dalton C Wamalwa, Elizabeth M Obimbo, Carey Farquhar, Barbra A Richardson, Dorothy A Mbori-Ngacha, Irene Inwani, Sara Benki-Nugent and Grace John-Stewart

    Citation: BMC Pediatrics 2010 10:33

    Content type: Research article

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  32. The co-existence of two genetically distinct metabolic disorders in the same patient has rarely been reported. Phenylketonuria (PKU) is an inborn error of the metabolism resulting from a phenylalanine hydroxyl...

    Authors: Daniela Concolino, Maria Rapsomaniki, Eliana Disabella, Simona Sestito, Maria G Pascale, Maria T Moricca, Giuseppe Bonapace, Elisea Arbustini and Pietro Strisciuglio

    Citation: BMC Pediatrics 2010 10:32

    Content type: Case report

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  33. Lactose intolerance is a common complication of diarrhoea in infants with malnutrition and a cause of treatment failure. A combination of nutritional injury and infectious insults in severe protein energy maln...

    Authors: Richard Nyeko, Israel Kalyesubula, Edison Mworozi and Hanifa Bachou

    Citation: BMC Pediatrics 2010 10:31

    Content type: Research article

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  34. Non-invasive ventilation (NIV) may be useful after extubation in children. Our objective was to determine postextubation NIV characteristics and to identify risk factors of postextubation NIV failure.

    Authors: Juan Mayordomo-Colunga, Alberto Medina, Corsino Rey, Andrés Concha, Sergio Menéndez, Marta Los Arcos and Irene García

    Citation: BMC Pediatrics 2010 10:29

    Content type: Research article

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  35. To determine the agents of poisoning and demographic distribution of children brought to Civil Hospital Karachi (CHK) with a history of accidental poison intake and to examine the factors associated with it.

    Authors: Nabeel Manzar, Syed Muhammad Ali Saad, Bushra Manzar and Syeda Shahzeen Fatima

    Citation: BMC Pediatrics 2010 10:28

    Content type: Research article

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  36. This randomized controlled trial aims to evaluate the effects of an early developmental intervention program on the development of young children in low- and low-middle-income countries who are at risk for neu...

    Authors: Jan L Wallander, Elizabeth McClure, Fred Biasini, Shivaprasad S Goudar, Omrana Pasha, Elwyn Chomba, Darlene Shearer, Linda Wright, Vanessa Thorsten, Hrishikesh Chakraborty, Sangappa M Dhaded, Niranjana S Mahantshetti, Roopa M Bellad, Zahid Abbasi and Waldemar Carlo

    Citation: BMC Pediatrics 2010 10:27

    Content type: Study protocol

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  37. The effects of intensive training for children with cerebral palsy (CP) remain uncertain. The aim of the study was to investigate the impact on motor function, quality of movements and everyday activities of t...

    Authors: Anne Brit Sorsdahl, Rolf Moe-Nilssen, Helga K Kaale, Jannike Rieber and Liv Inger Strand

    Citation: BMC Pediatrics 2010 10:26

    Content type: Research article

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  38. Cow's milk is the most common food allergen in infants and the diagnosis of cow's milk allergy is difficult, even with the use of several diagnostic tests. Therefore, elimination diets and challenge tests are ...

    Authors: Mário C Vieira, Mauro B Morais, José VN Spolidoro, Mauro S Toporovski, Ary L Cardoso, Gabriela TB Araujo, Victor Nudelman and Marcelo CM Fonseca

    Citation: BMC Pediatrics 2010 10:25

    Content type: Research article

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  39. Existing evidence indicates that once mature neonates with severe cardio-respiratory failure become eligible for Extra Corporeal Membrane Oxygenation (ECMO) their chances of intact survival are doubled if they...

    Authors: David J Field, Richard Firmin, Denis V Azzopardi, Frances Cowan, Edmund Juszczak and Peter Brocklehurst

    Citation: BMC Pediatrics 2010 10:24

    Content type: Study protocol

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  40. Raised intracranial pressure (ICP) is known to complicate both traumatic and non-traumatic encephalopathies. It impairs cerebral perfusion and may cause death due to global ischaemia and intracranial herniatio...

    Authors: Samson Gwer, Hellen Gatakaa, Leah Mwai, Richard Idro and Charles R Newton

    Citation: BMC Pediatrics 2010 10:23

    Content type: Research article

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  41. Diagnosis of neonatal infection is difficult, because of it's non-specific clinical presentation and the lack of reliable diagnostic tests. The purpose of this study was to examine the potential diagnostic val...

    Authors: J David M Edgar, Vanessa Gabriel, J Ruth Gallimore, Stanley A McMillan and Judith Grant

    Citation: BMC Pediatrics 2010 10:22

    Content type: Research article

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  42. Robust data on the prevalence of childhood disability and the circumstances and characteristics of disabled children is crucial to understanding the relationship between impairment and social disadvantage. It ...

    Authors: Clare M Blackburn, Nick J Spencer and Janet M Read

    Citation: BMC Pediatrics 2010 10:21

    Content type: Research article

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  43. Children at highest risk of developmental problems benefit from early identification and intervention. Investigating factors affecting child development at the time of transition to school may reveal opportuni...

    Authors: Suzanne C Tough, Jodi E Siever, Karen Benzies, Shirley Leew and David W Johnston

    Citation: BMC Pediatrics 2010 10:19

    Content type: Research article

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  44. Ethnic differences in the prevalence of asthma among children in the UK are under-researched. We aimed to determine the ethnic differences in the prevalence of asthma and atopic asthma in children from the mai...

    Authors: Melissa J Whitrow and Seeromanie Harding

    Citation: BMC Pediatrics 2010 10:18

    Content type: Research article

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  45. Muscle strength is important for young people with Down syndrome as they make the transition to adulthood, because their workplace activities typically emphasise physical rather than cognitive skills. Muscle s...

    Authors: Nora Shields, Nicholas F Taylor and Bo Fernhall

    Citation: BMC Pediatrics 2010 10:17

    Content type: Study protocol

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