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Neonatology

Section edited by Elizabeth Asztalos

This section considers studies regarding all aspects of neonatal health, disease, care, and outcomes.

Page 5 of 9

  1. The Bernese Pain Scale for Neonates (BPSN) is a multidimensional pain assessment tool that is already widely used in clinical settings in the German speaking areas of Europe. Recent findings indicate that pain...

    Authors: Eva Cignacco, Karin Schenk, Bonnie Stevens, Liliane Stoffel, Dirk Bassler, Sven Schulzke and Mathias Nelle

    Citation: BMC Pediatrics 2017 17:171

    Content type: Study protocol

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  2. Extremely preterm infants (≤ 28 weeks gestation) commonly require endotracheal intubation and mechanical ventilation (MV) to maintain adequate oxygenation and gas exchange. Given that MV is independently assoc...

    Authors: Wissam Shalish, Lara J. Kanbar, Smita Rao, Carlos A. Robles-Rubio, Lajos Kovacs, Sanjay Chawla, Martin Keszler, Doina Precup, Karen Brown, Robert E. Kearney and Guilherme M. Sant’Anna

    Citation: BMC Pediatrics 2017 17:167

    Content type: Study protocol

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  3. Compared to very low gestational age (<32 weeks, VLGA) cohorts, very low birth weight (<1500 g; VLBW) cohorts are more prone to selection bias toward small-for-gestational age (SGA) infants, which may impact u...

    Authors: Louise IM Koller-Smith, Prakesh S. Shah, Xiang Y. Ye, Gunnar Sjörs, Yueping A. Wang, Sharon S. W. Chow, Brian A. Darlow, Shoo K. Lee, Stellan Håkanson and Kei Lui

    Citation: BMC Pediatrics 2017 17:166

    Content type: Research article

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  4. Retinopathy of prematurity (ROP) still represents one of the leading causes of visual impairment in childhood. Systemic propranolol has proven to be effective in reducing ROP progression in preterm newborns, a...

    Authors: Luca Filippi, Giacomo Cavallaro, Elettra Berti, Letizia Padrini, Gabriella Araimo, Giulia Regiroli, Valentina Bozzetti, Chiara De Angelis, Paolo Tagliabue, Barbara Tomasini, Giuseppe Buonocore, Massimo Agosti, Angela Bossi, Gaetano Chirico, Salvatore Aversa, Roberta Pasqualetti…

    Citation: BMC Pediatrics 2017 17:165

    Content type: Study protocol

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  5. Approximately 8–23% of premature infants develop pulmonary hypertension (PH), and this diagnosis confers a higher possibility of mortality. As a result, professional societies recommend PH screening in prematu...

    Authors: Shilpa Vyas-Read, Usama Kanaan, Prabhu Shankar, Jane Stremming, Curtis Travers, David P. Carlton and Anne Fitzpatrick

    Citation: BMC Pediatrics 2017 17:163

    Content type: Research article

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  6. Neonatal mortality accounts for nearly three quarters of all infant deaths in Vietnam. The nursing team are the largest professional group working with newborns, however do not routinely receive neonatal train...

    Authors: Katie Gallagher, Colin Partridge, Hoang T Tran, Suzanna Lubran and Duncan Macrae

    Citation: BMC Pediatrics 2017 17:161

    Content type: Research article

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  7. The use of cord blood in the neonatal screening for glucose-6-phosphate dehydrogenase (G6PD) deficiency is being done with increasing frequency but has yet to be adequately evaluated against the use of periphe...

    Authors: Saif AlSaif, Ma. Bella Ponferrada, Khalid AlKhairy, Khalil AlTawil, Adel Sallam, Ibrahim Ahmed, Mohammed Khawaji, Khalid AlHathlol, Beverly Baylon, Ahmed AlSuhaibani and Mohammed AlBalwi

    Citation: BMC Pediatrics 2017 17:159

    Content type: Research article

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  8. Complications during pregnancy, childbirth and/or the postnatal period may result in the admission of a baby to a neonatal unit (NNU). While the survival and long-term prospects of high-risk infants are enhanc...

    Authors: Susan Kerr, Caroline King, Rhona Hogg, Kerri McPherson, Janet Hanley, Maggie Brierton and Sean Ainsworth

    Citation: BMC Pediatrics 2017 17:158

    Content type: Research article

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  9. According to WHO (2013) report the number of under five-year mortality in Ethiopia was 195,504, out of this 84,437 was from neonatal death and this mortality is related to immediate obstetric and newborn care ...

    Authors: Abadi Kidanemariam Berhe, Fitiwi Tinsae and Gebremedhin Gebreegziabher

    Citation: BMC Pediatrics 2017 17:157

    Content type: Research article

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  10. Infant birth weight, which is classified into low birth weight, normal birth weight and macrosomia, is associated with short and long-term health consequences, such as neonatal mortality and chronic disease in...

    Authors: Hayelom Gebrekirstos Mengesha, Alem Desta Wuneh, Berhe Weldearegawi and Divya L. Selvakumar

    Citation: BMC Pediatrics 2017 17:144

    Content type: Research article

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  11. Hypoxic Ischemic Encephalopathy (HIE) remains a problem of great concern worldwide especially in developing countries. The occurrence of a neurological syndrome can be an indicator of insult to the brain. We a...

    Authors: Irene N. Simiyu, Deborah N. Mchaile, Kahindo Katsongeri, Rune N. Philemon and Sia E. Msuya

    Citation: BMC Pediatrics 2017 17:131

    Content type: Research article

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  12. There are conflicting results in the literature on the impact of chorioamnionitis on neonatal respiratory morbidities. However, most studies are based on small clinical samples and fail to account for the comp...

    Authors: Amy Metcalfe, Sarka Lisonkova, Yasser Sabr, Amelie Stritzke and KS Joseph

    Citation: BMC Pediatrics 2017 17:128

    Content type: Research article

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  13. Early identification of infants at higher risk of developing bronchopulmonary dysplasia (BPD) may enable a targeted approach to reduce BPD. We aimed to evaluate the hypothesis that the interstitial pneumonia p...

    Authors: Hye-Rim Kim, Ji Young Kim, Bo La Yun, Byoungkook Lee, Chang Won Choi and Beyong Il Kim

    Citation: BMC Pediatrics 2017 17:125

    Content type: Research article

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  14. Low birth weight (Birth weight < 2500 g) is a leading cause of prenatal and neonatal deaths. The early identification of Low birth weight (LBW) neonates is essential for any comprehensive initiative to improve...

    Authors: Marta Yemane Hadush, Amanuel Hadgu Berhe and Araya Abrha Medhanyie

    Citation: BMC Pediatrics 2017 17:111

    Content type: Research article

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  15. Necrotizing enterocolitis (NEC) is a severe multifactorial disease in preterm neonates associated with high morbidity and mortality. Better insight into prognostic values of the many reported factors associate...

    Authors: Noor Samuels, Rob A. van de Graaf, Rogier C. J. de Jonge, Irwin K. M. Reiss and Marijn J. Vermeulen

    Citation: BMC Pediatrics 2017 17:105

    Content type: Research article

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  16. Each year 700,000 infants die due to intrapartum-related complications. Implementation of Helping Babies Breathe (HBB)-a simplified neonatal resuscitation protocol in low-resource clinical settings has shown t...

    Authors: Ashish KC, Johan Wrammert, Viktoria Nelin, Robert B. Clark, Uwe Ewald, Stefan Peterson and Mats Målqvist

    Citation: BMC Pediatrics 2017 17:103

    Content type: Research article

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  17. Neonatal hyperbilirubinemia has traditionally been screened by either total serum bilirubin or transcutaneous bilirubin. Whole blood bilirubin (TwB) by the GEM Premier 4000® blood gas analyzer (GEM) is a relat...

    Authors: Li Wang, Arianne Y. K. Albert, Benjamin Jung, Keyvan Hadad, Martha E. Lyon and Melanie Basso

    Citation: BMC Pediatrics 2017 17:92

    Content type: Research article

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  18. Previous studies have indicated edema may be involved in the pathophysiology following hypoxic-ischemic encephalopathy (HIE), and melatonin may exhibit neuro-protection against brain insults. However, little i...

    Authors: Li-Xiao Xu, Yuan Lv, Yan-Hong Li, Xin Ding, Ying Wang, Xing Han, Ming-Hua Liu, Bin Sun and Xing Feng

    Citation: BMC Pediatrics 2017 17:90

    Content type: Research article

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  19. In newborns and children, body fat estimation equations are often used at different ages than the age used to develop the equations. Limited validation studies exist for newborn body fat estimation equations a...

    Authors: Jennifer S. Cauble, Mira Dewi and Holly R. Hull

    Citation: BMC Pediatrics 2017 17:88

    Content type: Research article

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    The Correction to this article has been published in BMC Pediatrics 2020 20:92

  20. Some infants with congenital heart disease are at risk of in-hospital cardiac arrest. To better foresee cardiac arrest in infants with congenital heart disease, it might be useful to continuously assess end-or...

    Authors: Mirthe J. Mebius, Gideon J. du Marchie Sarvaas, Diana W. Wolthuis, Beatrijs Bartelds, Martin C. J. Kneyber, Arend F. Bos and Elisabeth M. W. Kooi

    Citation: BMC Pediatrics 2017 17:79

    Content type: Case report

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  21. Some etiological factors involved in developmental dysplasia of the hip (DDH) occur in the last trimester of pregnancy, which could result in a decreased incidence of DDH in preterm infants. The aim of this st...

    Authors: A. E. Lange, J. Lange, Till Ittermann, M. Napp, Paul-Christian Krueger, H. Bahlmann, R. Kasch and M. Heckmann

    Citation: BMC Pediatrics 2017 17:78

    Content type: Research article

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  22. While there are good data to describe changing trends in mortality and morbidity rates for preterm populations, there is very little information on the specific causes and pattern of death in terms of age of v...

    Authors: Tim Schindler, Louise Koller-Smith, Kei Lui, Barbara Bajuk and Srinivas Bolisetty

    Citation: BMC Pediatrics 2017 17:59

    Content type: Research article

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  23. Vancomycin has recently gained popularity as an empiric therapy for late onset sepsis in the NICU. Changes in resistance patterns in common organisms has resulted in targeting higher trough concentrations of v...

    Authors: Vidit Bhargava, Michael Malloy and Rafael Fonseca

    Citation: BMC Pediatrics 2017 17:50

    Content type: Research article

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  24. Handling neonates with postnatal respiratory failure due to congenital airway malformations implies knowledge about emergency management of unexpected difficult airway. In these stressful situations both techn...

    Authors: Beate Grass, Leopold Simma, Michael Reinehr, Urs Zimmermann, Claudine Gysin, Georg Henze and Vincenzo Cannizzaro

    Citation: BMC Pediatrics 2017 17:49

    Content type: Case report

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  25. In the UK, 1–2% of infants are born very preterm (<32 weeks of gestation) or have very low birth weight (<1500 g). Very preterm infants are initially unable to be fed nutritional volumes of milk and therefore ...

    Authors: Jane Abbott, Janet Berrington, Ursula Bowler, Elaine Boyle, Jon Dorling, Nicholas Embleton, Edmund Juszczak, Alison Leaf, Louise Linsell, Samantha Johnson, Kenny McCormick, William McGuire, Tracy Roberts and Ben Stenson

    Citation: BMC Pediatrics 2017 17:39

    Content type: Study protocol

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  26. Preterm neonates undergo many painful procedures as part of their standard care in the neonatal intensive care unit. However, pain treatment is inadequate in many of these routine procedures. In the present st...

    Authors: Jie Qiu, Yun-fei Jiang, Fang Li, Qian-hong Tong, Hui Rong and Rui Cheng

    Citation: BMC Pediatrics 2017 17:38

    Content type: Research article

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  27. Perinatal stroke is the leading cause of unilateral (hemiparetic) cerebral palsy, with life-long personal, social and financial consequences. Translational research findings indicate that early therapy interve...

    Authors: Anna Purna Basu, Janice Elizabeth Pearse, Jessica Baggaley, Rose Mary Watson and Tim Rapley

    Citation: BMC Pediatrics 2017 17:33

    Content type: Research article

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  28. This study aims to identify risk factors and the neurodevelopmental impact of neonatal hyperbilirubinemia in a limited-resource setting among a refugee and migrant population residing along the Thai-Myanmar bo...

    Authors: Laurence Thielemans, Margreet Trip-Hoving, Germana Bancone, Claudia Turner, Julie A. Simpson, Borimas Hanboonkunupakarn, Michaël Boele van Hensbroek, Patrick van Rheenen, Moo Kho Paw, François Nosten, Rose McGready and Verena I. Carrara

    Citation: BMC Pediatrics 2017 17:32

    Content type: Study protocol

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  29. Anaemia is one of the major causes of death among children under five years in Africa, with a prevalence of 64.6% among pre-school children. In 2014, we conducted a cross-sectional study in Namutumba district ...

    Authors: Fiona Kuziga, Yeka Adoke and Rhoda K. Wanyenze

    Citation: BMC Pediatrics 2017 17:25

    Content type: Research article

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  30. A patent ductus arteriosus (PDA) is frequently found in very preterm neonates and is associated with increased risk of morbidity and mortality. A shunt across a PDA can result in an unfavorable distribution of...

    Authors: Anna Sellmer, Bodil H. Bech, Jesper V. Bjerre, Michael R. Schmidt, Vibeke E. Hjortdal, Gitte Esberg, Søren Rittig and Tine B. Henriksen

    Citation: BMC Pediatrics 2017 17:7

    Content type: Research article

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  31. The indications and strategies for treatment of patent ductus arteriosus (PDA) are controversial, and the safety and long-term benefits of surgical PDA closure remain uncertain. The aim of this study was to co...

    Authors: Payman Barikbin, Hannes Sallmon, Silke Wilitzki, Joachim Photiadis, Christoph Bührer, Petra Koehne and Gerd Schmalisch

    Citation: BMC Pediatrics 2017 17:5

    Content type: Research article

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  32. Necrotizing enterocolitis (NEC) is a serious gastrointestinal disorder that is often seen in premature infants. Probiotics decrease the risk of NEC; however, the mechanism by which probiotics work is not clear...

    Authors: Wenshen Wu, Yanli Wang, Jingjing Zou, Fang Long, Huiheng Yan, Lijuan Zeng and Yunbin Chen

    Citation: BMC Pediatrics 2017 17:1

    Content type: Research article

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  33. Occurrence and consequence of cord blood (CB) vitamin D insufficiency/deficiency has not been adequately explored despite rising concern regarding this topic in pediatrics. This study was designed to determine...

    Authors: Ian Marshall, Rajeev Mehta, Charletta Ayers, Smita Dhumal and Anna Petrova

    Citation: BMC Pediatrics 2016 16:208

    Content type: Research article

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  34. The birth weight reference curve to estimate the newborns at risk in need of assessment and monitoring has been established. The previous reference curves from Indonesia, approximately 8 years ago, were based ...

    Authors: Ekawaty L. Haksari, Harrie N. Lafeber, Mohammad Hakimi, Endy P. Pawirohartono and Lennarth Nyström

    Citation: BMC Pediatrics 2016 16:188

    Content type: Research article

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  35. Late preterm infants account for the majority of preterm births. They are at an increased risk of neonatal mortality and morbidity and are less likely to initiate breastfeeding and to be exclusively breastfed ...

    Authors: Maria Lorella Giannì, Elena Bezze, Patrizio Sannino, Elena Stori, Laura Plevani, Paola Roggero, Massimo Agosti and Fabio Mosca

    Citation: BMC Pediatrics 2016 16:179

    Content type: Research article

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  36. The outcome of preterm infants has been varied in different hospitals and regions in developing countries. Regular clinical monitor are needed to know the effects of health care. This study aimed to describe t...

    Authors: XiangYong Kong, FengDan Xu, Rong Wu, Hui Wu, Rong Ju, XiaoLin Zhao, XiaoMei Tong, HongYan Lv, YanJie Ding, Fang Liu, Ping Xu, WeiPeng Liu, HongBin Cheng, TieQiang Chen, ShuJuan Zeng, WenZheng Jia…

    Citation: BMC Pediatrics 2016 16:174

    Content type: Research article

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  37. Pregnancies resulting through oocyte donation have been associated with increased risk for adverse outcomes for the mother, such as gestational hypertensive disorders. However, little is known about possible n...

    Authors: Evangelia Elenis, Gunilla Sydsjö, Alkistis Skalkidou, Claudia Lampic and Agneta Skoog Svanberg

    Citation: BMC Pediatrics 2016 16:170

    Content type: Research article

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  38. Perfusion index (PI) is becoming a part of clinical practice in neonatology to monitor peripheral perfusion noninvasively. Hemodynamic and respiratory changes occur in newborns during the transition period aft...

    Authors: Sezin Unal, Ebru Ergenekon, Selma Aktas, Serdar Beken, Nilgun Altuntas, Ebru Kazanci, Ferit Kulali, Ibrahim M. Hirfanoglu, Esra Onal, Canan Turkyilmaz, Esin Koc and Yildiz Atalay

    Citation: BMC Pediatrics 2016 16:164

    Content type: Research article

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  39. Due to clinical benefits, delayed cord clamping (DCC) is recommended in infants born before 37 weeks gestational age. The objective was to institute a delayed cord clamping program and to evaluate clinical out...

    Authors: Jeff Bolstridge, Tracy Bell, Barbara Dean, Amy Mackley, Gina Moore, Cheryl Swift, Dina Viscount, David A. Paul and Stephen A. Pearlman

    Citation: BMC Pediatrics 2016 16:155

    Content type: Research article

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  40. Thrombosis in neonates is commonly a central venous access device (CVAD) associated complication. Furthermore, a patent foramen ovale (PFO) is frequently seen in preterm infants. Even though a coincidence of b...

    Authors: Marlene Biermayr, Barbara Brunner, Kathrin Maurer, Rudolf Trawoeger, Ursula Kiechl-Kohlendorfer and Vera Neubauer

    Citation: BMC Pediatrics 2016 16:154

    Content type: Case report

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  41. Preterm infants follow an altered neurodevelopmental trajectory compared to their term born peers as a result of the influence of early birth, and the altered environment. Infant massage in the preterm infant ...

    Authors: Melissa M. Lai, Giulia D’Acunto, Andrea Guzzetta, Roslyn N. Boyd, Stephen E. Rose, Jurgen Fripp, Simon Finnigan, Naoni Ngenda, Penny Love, Koa Whittingham, Kerstin Pannek, Robert S. Ware and Paul B. Colditz

    Citation: BMC Pediatrics 2016 16:146

    Content type: Study protocol

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  42. Ganciclovir is a therapeutic choice for extremely premature infants with severe postnatal cytomegalovirus disease, but little is known about its optimal dose size and dosing interval for them.

    Authors: Mariko Sunada, Daisuke Kinoshita, Naoko Furukawa, Minako Kihara, Akira Nishimura, Masako Moriuchi and Hiroyuki Moriuchi

    Citation: BMC Pediatrics 2016 16:141

    Content type: Case report

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  43. Interventions to improve neonatal resuscitation are considered a priority for reducing neonatal mortality. In addition to training programs for health caregivers, the availability of adequate equipment in all ...

    Authors: Daniele Trevisanuto, Francesco Cavallin, Gaston Arnolda, Tran Dinh Chien, Ornella Lincetto, Ngo Minh Xuan, Nguyen Viet Tien, Nguyen Thi Xuan Hoi and Luciano Moccia

    Citation: BMC Pediatrics 2016 16:139

    Content type: Research article

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  44. When a newborn requires neonatal intensive care unit (NICU) hospitalization, parent and infant experience an unusual often prolonged separation. This critical care environment poses challenges to parent-infant...

    Authors: Nancy Feeley, Christine Genest, Hannakaisa Niela-Vilén, Lyne Charbonneau and Anna Axelin

    Citation: BMC Pediatrics 2016 16:134

    Content type: Research article

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  45. Infections are the single most important cause of neonatal mortality in developing countries. Results from trials in Asia evaluating the effect of chlorhexidine on neonatal mortality have been encouraging but ...

    Authors: Sushma Nangia, Usha Dhingra, Pratibha Dhingra, Arup Dutta, Venugopal P. Menon, Robert E. Black and Sunil Sazawal

    Citation: BMC Pediatrics 2016 16:121

    Content type: Research article

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  46. Low/medium income countries, with health inequalities present high rates of neonates having low birthweight and/or are small for the gestational age. This study aims to analyze the absolute and relative income...

    Authors: Ana D. I. Sadovsky, Alicia Matijasevich, Iná S. Santos, Fernando C. Barros, Angelica E. Miranda and Mariangela F. Silveira

    Citation: BMC Pediatrics 2016 16:115

    Content type: Research article

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  47. The extent of lung hypoplasia in neonates with congenital diaphragmatic hernia (CDH) can be assessed from gas exchange. We examined the role of preductal capillary blood gases in prognosticating outcome in pat...

    Authors: Ruža Grizelj, Katarina Bojanić, Ena Pritišanac, Tomislav Luetić, Jurica Vuković, Toby N. Weingarten, Darrell R. Schroeder and Juraj Sprung

    Citation: BMC Pediatrics 2016 16:114

    Content type: Research article

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