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Neonatology

Section edited by Elizabeth Asztalos

This section considers studies regarding all aspects of neonatal health, disease, care, and outcomes.

Page 4 of 9

  1. Despite worldwide efforts to reduce neonatal mortality, 44% of under-five deaths occur in the first 28 days of life. The primary causes of neonatal death are preventable or treatable. This study describes the ...

    Authors: Merab Nyishime, Ryan Borg, Willy Ingabire, Bethany Hedt-Gauthier, Evrard Nahimana, Neil Gupta, Anne Hansen, Michelle Labrecque, Fulgence Nkikabahizi, Christine Mutaganzwa, Francois Biziyaremye, Claudine Mukayiranga, Francine Mwamini and Hema Magge

    Citation: BMC Pediatrics 2018 18:353

    Content type: Research article

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  2. Congenital bilateral vocal cord paralysis is a rare occurrence. Approximately half the cases are associated with a major comorbidity, usually neurological, neuromuscular or malformative.

    Authors: Camille Brotelande, Nicolas Leboucq, Mohamed Akkari, Thomas Roujeau, Massimo Di Maio, Christophe Milési, Michel Mondain, Charles Raybaud and Gilles Cambonie

    Citation: BMC Pediatrics 2018 18:351

    Content type: Case report

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  3. Preterm infants are especially vulnerable to pain. The intensive treatment often necessary for their survival unfortunately includes many painful interventions and procedures. Untreated pain can lead to both s...

    Authors: Emma Olsson, Agneta Anderzén-Carlsson, Sigríður María Atladóttir, Anna Axelin, Marsha Campbell-Yeo, Mats Eriksson, Guðrún Kristjánsdóttir, Emilia Peltonen, Bonnie Stevens, Bente Vederhus and Randi Dovland Andersen

    Citation: BMC Pediatrics 2018 18:349

    Content type: Research article

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  4. Neonatal severe primary hyperparathyroidism (NSHPT) is a rare autosomal recessive disorder of calcium homeostasis, characterized by striking hyperparathyroidism, marked hypercalcemia and hyperparathyroid bone ...

    Authors: Manuela Capozza, Iolanda Chinellato, Vito Guarnieri, Natascia Di lorgi, Maria Accadia, Cristina Traggiai, Girolamo Mattioli, Antonio Di Mauro and Nicola Laforgia

    Citation: BMC Pediatrics 2018 18:340

    Content type: Case report

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    The Correction to this article has been published in BMC Pediatrics 2019 19:463

  5. There is evidence that delivery room resuscitation of very preterm infants often deviates from internationally recommended guidelines. There were no published data in Spain regarding the quality of neonatal re...

    Authors: Silvia Maya-Enero, Francesc Botet-Mussons, Josep Figueras-Aloy, Montserrat Izquierdo-Renau, Marta Thió and Martin Iriondo-Sanz

    Citation: BMC Pediatrics 2018 18:319

    Content type: Research article

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  6. Childhood mortality remains high in resource-limited third world countries. Most childhood deaths in hospital often occur within the first 24 h of admission. Many of these deaths are from preventable causes. T...

    Authors: Gemechu Jofiro, Kemal Jemal, Lemlem Beza and Tigist Bacha Heye

    Citation: BMC Pediatrics 2018 18:316

    Content type: Research article

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  7. This study compares the minimally invasive Bilistick and a noninvasive method with standard Total Serum Bilirubin (TSB) measurement in preterm newborns receiving phototherapy. We assess the agreement of Transc...

    Authors: Rinawati Rohsiswatmo, Hanifah Oswari, Radhian Amandito, Hikari Ambara Sjakti, Endang Windiastuti, Rosalina Dewi Roeslani and Indrayady Barchia

    Citation: BMC Pediatrics 2018 18:315

    Content type: Research article

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  8. Stimulation is the most common intervention during neonatal resuscitation at birth, but scarce information is available on the actual methods, timing and efficacy of this basic step. To evaluate the occurrence...

    Authors: Andrea Pietravalle, Francesco Cavallin, Anna Opocher, Stefania Madella, Maria Elena Cavicchiolo, Damiano Pizzol, Giovanni Putoto and Daniele Trevisanuto

    Citation: BMC Pediatrics 2018 18:306

    Content type: Research article

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  9. Neonatal hypoxic-ischemic encephalopathy (HIE) commonly leads to neurodevelopmental impairment, raising the need for prognostic tools which may guide future therapies in time. Prognostic value of proton MR spe...

    Authors: Hajnalka Barta, Agnes Jermendy, Marton Kolossvary, Lajos R. Kozak, Andrea Lakatos, Unoke Meder, Miklos Szabo and Gabor Rudas

    Citation: BMC Pediatrics 2018 18:302

    Content type: Research article

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  10. Congenital brain lesions expose infants to be at high-risk for being affected by neurodevelopmental disorders such as cerebral palsy (CP). Early interventions programs can significantly impact and improve thei...

    Authors: Giuseppina Sgandurra, Elena Beani, Matteo Giampietri, Riccardo Rizzi and Giovanni Cioni

    Citation: BMC Pediatrics 2018 18:295

    Content type: Study protocol

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  11. Although persistent pulmonary hypertension of the newborn (PPHN) and infantile hypertrophic pyloric stenosis (HPS) are both well-known diseases that occur in early infancy, PPHN complicated by HPS is rare. As ...

    Authors: Shigeo Iijima, Daizo Ueno, Toru Baba and Akira Ohishi

    Citation: BMC Pediatrics 2018 18:290

    Content type: Case report

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  12. Intraventricular hemorrhage (IVH) is a frequent complication in extreme and very preterm births. Despite a high risk of death and impaired neurodevelopment, the precise prognosis of infants with IVH remains un...

    Authors: Vianney Gilard, Alexandra Chadie, François-Xavier Ferracci, Marie Brasseur-Daudruy, François Proust, Stéphane Marret and Sophie Curey

    Citation: BMC Pediatrics 2018 18:288

    Content type: Research article

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  13. The supply of breast milk to preterm infants tends to occur at a lower rate than that recorded among term infants. We aimed to investigate the facilitators of and barriers to breastfeeding during hospital stay...

    Authors: Maria Lorella Gianni, Elena Nicoletta Bezze, Patrizio Sannino, Michela Baro, Paola Roggero, Salvatore Muscolo, Laura Plevani and Fabio Mosca

    Citation: BMC Pediatrics 2018 18:283

    Content type: Research article

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  14. Survival of preterm neonates has steadily improved over the past five decades, due to changes in the neonatal intensive care. However, in Saudi Arabia, there are no written guidelines on the definition of the ...

    Authors: Mostafa A. Abolfotouh, Saif Al Saif, Waleed A. Altwaijri and Mohammed A. Al Rowaily

    Citation: BMC Pediatrics 2018 18:280

    Content type: Research article

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  15. Sick newborns in neonatal units who are unable to breastfeed are fed expressed breast milk. In Sri Lanka, most mothers stay in hospital throughout baby’s stay to provide this milk freshly. In other countries m...

    Authors: Ranmali Rodrigo, Lisa H. Amir and Della A. Forster

    Citation: BMC Pediatrics 2018 18:271

    Content type: Research article

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  16. Necrotizing enterocolitis (NEC) is a leading cause of neonatal morbidity and mortality in premature infants. To date, no effective biomarkers exist to predict which premature infants will develop NEC, limiting...

    Authors: Terri Marin, Ravi M. Patel, John D. Roback, Sean R. Stowell, Ying Guo, Kirk Easley, Megan Warnock, Jane Skvarich and Cassandra D. Josephson

    Citation: BMC Pediatrics 2018 18:270

    Content type: Study protocol

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  17. Preterm infants are high risk for delayed neurodevelopment. The main goal is to develop a program of early intervention for very preterm infants that allows families to apply it continuously at home, and quant...

    Authors: Rita C. Silveira, Eliane Wagner Mendes, Rubia Nascimento Fuentefria, Nadia Cristina Valentini and Renato S. Procianoy

    Citation: BMC Pediatrics 2018 18:268

    Content type: Study protocol

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  18. Seven years of age is a milestone for learning basic knowledge that is strongly related to attention abilities such as Alerting, Orienting, and Inhibition function, allowing for appropriate adaptation to prima...

    Authors: Hadrien Ceyte, Joëlle Rosenbaum, Isabelle Hamon, Maëlle Wirth, Sébastien Caudron and Jean-Michel Hascoët

    Citation: BMC Pediatrics 2018 18:264

    Content type: Study protocol

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  19. Neonatal hypothermia is a worldwide problem and an important contributing factor for Neonatal morbidity and mortality especially in developing countries. High prevalence of hypothermia has been reported from c...

    Authors: Birhanu Wondimeneh Demissie, Balcha Berhanu Abera, Tesfaye Yitna Chichiabellu and Feleke Hailemichael Astawesegn

    Citation: BMC Pediatrics 2018 18:263

    Content type: Research article

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  20. Much controversy exists about the optimal management of a patent ductus arteriosus (PDA) in preterm infants, especially in those born at a gestational age (GA) less than 28 weeks. No causal relationship has be...

    Authors: Tim Hundscheid, Wes Onland, Bart van Overmeire, Peter Dijk, Anton H. L. C. van Kaam, Koen P. Dijkman, Elisabeth M. W. Kooi, Eduardo Villamor, André A. Kroon, Remco Visser, Daniel C. Vijlbrief, Susanne M. de Tollenaer, Filip Cools, David van Laere, Anne-Britt Johansson, Catheline Hocq…

    Citation: BMC Pediatrics 2018 18:262

    Content type: Study protocol

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  21. The death of a child before or shortly after birth is frequently preceded by an end-of-life decision (ELD). Population-based studies of incidence and characteristics of ELDs in neonates and infants are rare, a...

    Authors: Laure Dombrecht, Kim Beernaert, Ellen Roets, Kenneth Chambaere, Filip Cools, Linde Goossens, Gunnar Naulaers, Luc De Catte, Joachim Cohen and Luc Deliens

    Citation: BMC Pediatrics 2018 18:260

    Content type: Study protocol

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  22. Hypoxic-ischemic encephalopathy (HIE) is a rare neonatal condition affecting about 1‰ births. Despite a significant improvement in the management of this condition in the last ten years, HIE remains associated...

    Authors: Thierry Debillon, Nathalie Bednarek and Anne Ego

    Citation: BMC Pediatrics 2018 18:255

    Content type: Study protocol

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  23. Sepsis is a leading cause of morbidity and mortality among newborns. C-reactive protein (CRP) and procalcitonin (PCT) have some limitations in the diagnosis of preterm neonatal sepsis. In this study, the cut-o...

    Authors: C. Aydemir, H. Aydemir, F. Kokturk, C. Kulah and A. G. Mungan

    Citation: BMC Pediatrics 2018 18:253

    Content type: Research article

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  24. Unlicensed and off label drug use is an issue recognized worldwide in pediatric pharmacotherapy. The study was designed to assess the prevalence and predictors of unlicensed and off label drug use in neonatal ...

    Authors: Muhammad Aamir, Jamshaid Ali Khan, Faisal Shakeel, Rabeea Shareef and Nazia Shah

    Citation: BMC Pediatrics 2018 18:242

    Content type: Research article

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  25. Early discharge of very low birth weight infant (VLBW) in low resource settings is inevitable but to minimize mortality of these infants after discharge we need to identify the death attributes.

    Authors: Yaser Abdallah, Flavia Namiiro, Jolly Nankunda, Jamiru Mugalu and Yvonne Vaucher

    Citation: BMC Pediatrics 2018 18:239

    Content type: Research article

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  26. Delayed cord clamping is the standard of care in infants not requiring resuscitation; however effects of cord clamping strategies have not been evaluated systematically in small for gestational age (SGA) infan...

    Authors: Abhishek Chopra, Anup Thakur, Pankaj Garg, Neelam Kler and Kanwal Gujral

    Citation: BMC Pediatrics 2018 18:234

    Content type: Research article

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  27. Measurement of transcutaneous bilirubin (TcB) is a quick, reliable and painless method to guide management of hyperbilirubinemia. Studies in term and late preterm infants have found that TcB measurements from ...

    Authors: Vidit Bhargava, Daniel Tawfik, Bruce Niebuhr and Sunil K. Jain

    Citation: BMC Pediatrics 2018 18:227

    Content type: Research article

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  28. Various intervention programs exist for parents of preterm babies and some systematic reviews (SRs) have synthesised the evidence of their effectiveness. These reviews are, however, limited to specific interve...

    Authors: Shuby Puthussery, Muhammad Chutiyami, Pei-Ching Tseng, Lesley Kilby and Jogesh Kapadia

    Citation: BMC Pediatrics 2018 18:223

    Content type: Research article

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  29. Babies born at moderate-late preterm gestations account for > 80% of all preterm births. Although survival is excellent, these babies are at increased risk of adverse neurodevelopmental outcomes. They also are...

    Authors: Frank H. Bloomfield, Jane E. Harding, Michael P. Meyer, Jane M. Alsweiler, Yannan Jiang, Clare R. Wall and Tanith Alexander

    Citation: BMC Pediatrics 2018 18:220

    Content type: Study protocol

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  30. Generalized Arterial Calcification of Infancy (GACI) is a heritable ectopic mineralization disorder resulting in diffuse arterial calcifications and/or stenosis, mostly caused by mutations in the ENPP1 gene. Here...

    Authors: Iole Brunod, Barthélémy Tosello, Sophie Hassid, Catherine Gire, Laurent Thomachot and Michel Panuel

    Citation: BMC Pediatrics 2018 18:217

    Content type: Case report

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  31. Very preterm birth (24 to < 32 week’s gestation) is a major public health issue due to its prevalence, the clinical and ethical questions it raises and the associated costs. It raises two major clinical and et...

    Authors: Isabelle Aujoulat, Séverine Henrard, Anne Charon, Anne-Britt Johansson, Jean-Paul Langhendries, Anne Mostaert, Danièle Vermeylen and Gaston Verellen

    Citation: BMC Pediatrics 2018 18:206

    Content type: Research article

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  32. Neonatal hyperbilirubinaemia is one of the commonest causes of hospital visit in the neonatal period. When severe, it is a leading cause of irreversible neurological and musculoskeletal disability. Prompt reco...

    Authors: Chidiebere D. I. Osuorah, Uchenna Ekwochi and Isaac N. Asinobi

    Citation: BMC Pediatrics 2018 18:202

    Content type: Research article

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  33. Indirect neonatal hyperbilirubinemia (INH) is a common neonatal disorder worldwide which can remain benign if prompt management is available. However there is a higher morbidity and mortality risk in settings ...

    Authors: L. Thielemans, M. Trip-Hoving, J. Landier, C. Turner, T. J. Prins, E. M. N. Wouda, B. Hanboonkunupakarn, C. Po, C. Beau, M. Mu, T. Hannay, F. Nosten, B. Van Overmeire, R. McGready and V. I. Carrara

    Citation: BMC Pediatrics 2018 18:190

    Content type: Research article

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  34. Considering the significant prevalence of Neonatal Indirect Hyperbilirubinemia (NIH) and its irreversible neurological complications, identifying the factors involved in the prevalence of neonatal jaundice is ...

    Authors: Shahrokh Mehrpisheh, Azadeh Memarian, Abolfazl Mahyar and Negin Sadat Valiahdi

    Citation: BMC Pediatrics 2018 18:178

    Content type: Research article

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  35. To investigate the trends in the incidence and associated factors of late-onset sepsis (LOS) associated with improved survival in extremely preterm infants.

    Authors: Jin Kyu Kim, Yun Sil Chang, Sein Sung, So Yoon Ahn and Won Soon Park

    Citation: BMC Pediatrics 2018 18:172

    Content type: Research article

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  36. About three – quarters of all neonatal deaths occur during the first week of life, with over half of these occurring within the first 24 h after birth. The first minutes after birth are critical to reducing ne...

    Authors: Duncan N. Shikuku, Benson Milimo, Elizabeth Ayebare, Peter Gisore and Gorrette Nalwadda

    Citation: BMC Pediatrics 2018 18:167

    Content type: Research article

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  37. Feeding breast milk is associated with reduced morbidity and mortality, as well as improved neurodevelopmental outcome but does not meet the high nutritional requirements of preterm infants. Both plasma and ur...

    Authors: Michaela Mathes, Christoph Maas, Christine Bleeker, Julia Vek, Wolfgang Bernhard, Andreas Peter, Christian F. Poets and Axel R. Franz

    Citation: BMC Pediatrics 2018 18:154

    Content type: Research article

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  38. Inhaled corticosteroids (ICS) offer targeted treatment for bronchopulmonary dysplasia (BPD) with minimal systemic effects compared to systemic steroids. However, dosing of ICS in the management of infants at h...

    Authors: Kamini Raghuram, Michael Dunn, Krista Jangaard, Maureen Reilly, Elizabeth Asztalos, Edmond Kelly, Michael Vincer and Vibhuti Shah

    Citation: BMC Pediatrics 2018 18:153

    Content type: Research article

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  39. There is increasing evidence that neonatal seizures in term neonates with stroke, asphyxia or brain haemorrhage might be associated with adverse neurodevelopment and development of epilepsy. The extent of this...

    Authors: T. R. De Haan, J. Langeslag, J. H. van der Lee and A. H. van Kaam

    Citation: BMC Pediatrics 2018 18:147

    Content type: Research article

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  40. The point prevalence of Clostridium difficile stool shedding in hospitalized infants from two neonatal intensive care units (NICUs) was examined utilizing standard clinical testing compared with duplex PCR to ide...

    Authors: Andrea Green Hines, Alison Freifeld, Xing Zhao, Ann Anderson Berry, Lynne Willett, Peter C. Iwen and Kari A. Simonsen

    Citation: BMC Pediatrics 2018 18:137

    Content type: Research article

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  41. Infants in Neonatal Intensive Care Units represent a heavily transfused population, and are the focus of much research interest. Such research commonly relies on custom research databases or routinely collecte...

    Authors: Jillian A. Patterson, Jennifer R. Bowen, Sally Francis and Jane B. Ford

    Citation: BMC Pediatrics 2018 18:86

    Content type: Research article

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  42. Orally administered sucrose is effective and safe in reducing pain intensity during single, tissue-damaging procedures in neonates, and is commonly recommended in neonatal pain guidelines. However, there is wi...

    Authors: Bonnie Stevens, Janet Yamada, Marsha Campbell-Yeo, Sharyn Gibbins, Denise Harrison, Kimberley Dionne, Anna Taddio, Carol McNair, Andrew Willan, Marilyn Ballantyne, Kimberley Widger, Souraya Sidani, Carole Estabrooks, Anne Synnes, Janet Squires, Charles Victor…

    Citation: BMC Pediatrics 2018 18:85

    Content type: Research article

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  43. In critically ill (preterm) neonates, central venous catheters (CVCs) are increasingly used for administration of medication or parenteral nutrition. A serious complication, however, is the development of cath...

    Authors: Jeanine J. Sol, Moniek van de Loo, Marit Boerma, Klasien A. Bergman, Albertine E. Donker, Mark A. H. B. M. van der Hoeven, Christiaan V. Hulzebos, Ronny Knol, K. Djien Liem, Richard A. van Lingen, Enrico Lopriore, Monique H. Suijker, Daniel C. Vijlbrief, Remco Visser, Margreet A. Veening, Mirjam M. van Weissenbruch…

    Citation: BMC Pediatrics 2018 18:84

    Content type: Study protocol

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  44. Therapeutic hypothermia is neuroprotective in asphyxiated neonates by counteracting mechanisms contributing to brain injury. Although an initial increased permeability is part of an inflammatory reaction and t...

    Authors: Hans Jørgen Timm Guthe, Torbjørn Nedrebø, Jan Kristian Damås, Helge Wiig and Ansgar Berg

    Citation: BMC Pediatrics 2018 18:82

    Content type: Research article

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