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Neonatology

Section edited by Elizabeth Asztalos

This section considers studies regarding all aspects of neonatal health, disease, care, and outcomes.

Page 1 of 8

  1. Prematurity is the leading cause of mortality in children under 5 years of age globally and is also frequently associated with postnatal growth failure (PGF). Although most preterm births occur in low resource...

    Authors: Clare Nakubulwa, Victor Musiime, Flavia B. Namiiro, James K Tumwine, Christine Hongella, James Nyonyintono, Anna B. Hedstrom and Robert Opoka

    Citation: BMC Pediatrics 2020 20:86

    Content type: Research article

    Published on:

  2. Clostridium perfringens forms part of the human gut microbiota and has been associated with life-threatening necrotising enterocolitis (NEC) in premature infants. Whether specific toxigenic strains are responsibl...

    Authors: Alexander G. Shaw, Emma Cornwell, Kathleen Sim, Hannah Thrower, Hannah Scott, Joseph C. S. Brown, Ronald A. Dixon and J. Simon Kroll

    Citation: BMC Pediatrics 2020 20:75

    Content type: Research article

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  3. Different charts are used to assess premature growth. The Fenton chart, based on prenatal growth, has been used in the neonates’ intensive care unit (NICU) of the Notre Dame des Secours University Hospital to ...

    Authors: Marie Samarani, Gianna Restom, Joelle Mardini, Georges Abi Fares, Souheil Hallit and Marie-Claude Fadous Khalife

    Citation: BMC Pediatrics 2020 20:74

    Content type: Research article

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  4. Neonatal mortality remains a serious global public health problem, but Sub-Saharan Africa (SSA), in particular, is largely affected. Current evidence on neonatal mortality is essential to inform programs and p...

    Authors: Animut Alebel, Fasil Wagnew, Pammla Petrucka, Cheru Tesema, Nurilign Abebe Moges, Daniel Bekele Ketema, lieltework Yismaw, Mamaru Wubale Melkamu, Yitbarek Tenaw Hibstie, Belisty Temesgen, Zebenay Workneh Bitew, Animen Ayehu Tadesse and Getiye Dejenu Kibret

    Citation: BMC Pediatrics 2020 20:72

    Content type: Research article

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  5. The first consensus standardised neonatal parenteral nutrition formulations were implemented in many neonatal units in Australia in 2012. The current update involving 49 units from Australia, New Zealand, Sing...

    Authors: Srinivas Bolisetty, David Osborn, Tim Schindler, John Sinn, Girish Deshpande, Chee Sing Wong, Susan E. Jacobs, Nilkant Phad, Pramod Pharande, Rodney Tobiansky, Melissa Luig, Amit Trivedi, Joanne Mcintosh, Eszter Josza, Gillian Opie, Lyn Downe…

    Citation: BMC Pediatrics 2020 20:59

    Content type: Correspondence

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  6. Neonatal sepsis is an invasive infection, usually bacterial, and often occurring during the neonatal period (0–28 days). Neonatal sepsis causes a high burden of morbidity and mortality in developing countries ...

    Authors: Amare Belachew and Tilahun Tewabe

    Citation: BMC Pediatrics 2020 20:55

    Content type: Research article

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  8. Improved neonatal care has resulted in increased survival rates among infants born after only 22 gestational weeks, but extremely preterm children still have an increased risk of neurodevelopmental delays, lea...

    Authors: Erika Baraldi, Mara Westling Allodi, Kristina Löwing, Ann-Charlotte Smedler, Björn Westrup and Ulrika Ådén

    Citation: BMC Pediatrics 2020 20:49

    Content type: Study protocol

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  9. In Canada alone, almost 3000 VLBW infants are born and treated annually with almost 1200 going onto death or survival with severe brain injury, chronic lung disorders, aggressive retinopathy of prematurity, la...

    Authors: Elizabeth V. Asztalos, Keith Barrington, Abhay Lodha, William Tarnow-Mordi and Andrew Martin

    Citation: BMC Pediatrics 2020 20:40

    Content type: Study protocol

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  10. The well-being of mothers of infants requiring Neonatal Intensive Care Unit (NICU) hospitalization may be affected by the architectural design of the unit. A few recent studies suggest there may be some drawba...

    Authors: Nancy Feeley, Stephanie Robins, Christine Genest, Robyn Stremler, Phyllis Zelkowitz and Lyne Charbonneau

    Citation: BMC Pediatrics 2020 20:38

    Content type: Research article

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  11. Neonatal seizures are difficult to diagnose and, when they are, tradition dictates first line treatment is phenobarbital. There is little data on how consultants diagnose neonatal seizures, choose when to trea...

    Authors: Lucy Gossling, James J. P. Alix, Theocharis Stavroulakis and Anthony R. Hart

    Citation: BMC Pediatrics 2020 20:36

    Content type: Research article

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  12. Adverse birth outcome which attributes to most perinatal deaths is an important indicator of child health and survival. Hence, this study aims to identify determinants of adverse birth outcome among mothers wh...

    Authors: Helen Tsehaye Hailemichael, Gurmesa Tura Debelew, Haileselasie Berhane Alema, Meresa Gebremedhin Weldu and Kebede Haile Misgina

    Citation: BMC Pediatrics 2020 20:10

    Content type: Research article

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  13. Perinatal decision-making affects outcomes for extremely preterm babies (22–26 weeks’ gestational age (GA)): more active units have improved survival without increased morbidity. We hypothesised such units may...

    Authors: Andrei Scott Morgan, Babak Khoshnood, Caroline Diguisto, Laurence Foix L’Helias, Laetitia Marchand-Martin, Monique Kaminski, Jennifer Zeitlin, Gérard Bréart, François Goffinet and Pierre-Yves Ancel

    Citation: BMC Pediatrics 2020 20:8

    Content type: Research Article

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  14. Natural vegetable oils are widely used for newborn massage in many low resource settings. Animal models indicated that sunflower seed oil (SSO) can accelerate skin barrier recovery following damage, while othe...

    Authors: Aimee Summers, Marty O. Visscher, Subarna K. Khatry, Jeevan B. Sherchand, Steven C. LeClerq, Joanne Katz, James M. Tielsch and Luke C. Mullany

    Citation: BMC Pediatrics 2019 19:512

    Content type: Research article

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  15. The neonatal period is the most vulnerable time for child survival. The declines in the neonatal mortality rate have been slower than the post-neonatal under-five mortality rate in the majority of countries. T...

    Authors: Abera Mersha, Agegnehu Bante and Shitaye Shibiru

    Citation: BMC Pediatrics 2019 19:499

    Content type: Research article

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  16. This study aims to investigate the application value of three-dimensional arterial spin labeling (3DASL) in investigating cerebral blood flow dynamics in full-term neonates.

    Authors: Jia-Ning Wang, Jia Li, Huai-Jun Liu, Xiao-Ping Yin, Huan Zhou, Ya-Ting Zheng, Na An, Si Liang and Zuo-Jun Geng

    Citation: BMC Pediatrics 2019 19:495

    Content type: Research article

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  18. Colon stenosis and acute appendicitis are rare diseases among premature babies. To the best of our knowledge, no study has identified both the conditions in preterm babies.

    Authors: Takuto Naito, Hiromu Teramen, Hiroaki Hayashi, Mai Takegawa, Haruko Sakamoto, Toshihide Shimada, Koichi Ohno and Misao Yoshii

    Citation: BMC Pediatrics 2019 19:492

    Content type: Case report

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  19. The objective of the study was to evaluate data on early-onset neonatal invasive infections in western Sweden for the period 1997–2017. To identify changes in incidence, etiology and mortality and compare to p...

    Authors: Margrét Johansson Gudjónsdóttir, Anders Elfvin, Elisabet Hentz, Ingegerd Adlerberth, Ingemar Tessin and Birger Trollfors

    Citation: BMC Pediatrics 2019 19:490

    Content type: Research article

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  20. There is increasing evidence that intrauterine environment and, consequently, growth in utero have both immediate and far-reaching consequences for health. Neonatal body composition might be a more sensitive m...

    Authors: Cornelia Wiechers, Sara Kirchhof, Christoph Maas, Christian F. Poets and Axel R. Franz

    Citation: BMC Pediatrics 2019 19:489

    Content type: Research article

    Published on:

    The Research article to this article has been published in BMC Pediatrics 2019 19:488

  21. During pregnancy, a variety of factors can influence fetal growth and development. Intrauterine growth may impact on later life and health. Neonatal body composition may be a more sensitive marker for the intr...

    Authors: Cornelia Wiechers, Sara Kirchhof, Lena Balles, Vanessa Avelina, Romy Weber, Christoph Maas, Jan Pauluschke-Fröhlich, Manfred Hallschmid, Hubert Preißl, Andreas Fritsche, Christian F. Poets and Axel R. Franz

    Citation: BMC Pediatrics 2019 19:488

    Content type: Research article

    Published on:

    The Research article to this article has been published in BMC Pediatrics 2019 19:489

  22. Nutritive sucking is a complex activity, the biomechanical components of which may vary in relation to respiratory phase, swallow-rate per minute, suck-swallow ratio, and swallow non-inspiratory flow (SNIF). Q...

    Authors: M. L. J. Lagarde, N. van Alfen, S. A. F. de Groot, A. C. H. Geurts and L. van den Engel-Hoek

    Citation: BMC Pediatrics 2019 19:477

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Pediatrics 2020 20:44

  23. Recent guidelines recommend a cranial ultrasound (CU) in neonates born at < 30 weeks gestation, admitted to the neonatal intensive care unit (NICU), or with a CU indication. Here, we addressed the need to exte...

    Authors: Judith Weise, Matthias Heckmann, Hagen Bahlmann, Till Ittermann, Heike Allenberg, Grzegorz Domanski and Anja Erika Lange

    Citation: BMC Pediatrics 2019 19:476

    Content type: Research article

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  24. The purpose of this study was to examine differences in attitudes to feeding in neonates with Gastroschisis between clinical groups and to develop a standardized feeding protocol. Confusion, inconsistencies in...

    Authors: Donna Hobson, Kaye Spence, Amit Trivedi and Gordon Thomas

    Citation: BMC Pediatrics 2019 19:475

    Content type: Research article

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  25. Family Centered Care (FCC) has been widely adopted as the framework for caring for infants in the Neonatal Intensive Care Unit (NICU) but it is not uniformly defined or practiced, making it difficult to determ...

    Authors: Linda S. Franck, Rebecca M. Kriz, Robin Bisgaard, Diana M. Cormier, Priscilla Joe, Pamela S. Miller, Jae H. Kim, Carol Lin and Yao Sun

    Citation: BMC Pediatrics 2019 19:469

    Content type: Study protocol

    Published on:

  26. This study aims to provide guidance for clinical work through analysis of the clinical characteristics, endoscopic and pathological manifestations, diagnosis, and treatment of an 18-day-old neonate with exfoli...

    Authors: Zu-Qin Yang, Jing-Yun Mai, Min-Li Zhu, Xiu-Man Xiao, Xiao-Xiao He, Shang-Qin Chen and Zhen-Lang Lin

    Citation: BMC Pediatrics 2019 19:464

    Content type: Case report

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  27. Gaining a better understanding of the probability, timing and prediction of rehospitalisation amongst preterm babies could help improve outcomes. There is limited research addressing these topics amongst extre...

    Authors: Robert Anthony Reed, Andrei Scott Morgan, Jennifer Zeitlin, Pierre-Henri Jarreau, Héloïse Torchin, Véronique Pierrat, Pierre-Yves Ancel and Babak Khoshnood

    Citation: BMC Pediatrics 2019 19:451

    Content type: Research article

    Published on:

  28. Stress signals during sucking activity such as nasal flaring, head turning, and extraneous movements of the body have been attributed to incoordination of sucking, swallowing, and respiration (SSR) in prematur...

    Authors: You Gyoung Yi, Byung-Mo Oh, Seung Han Shin, Jin Yong Shin, Ee-Kyung Kim and Hyung-Ik Shin

    Citation: BMC Pediatrics 2019 19:440

    Content type: Research article

    Published on:

  29. With the rapid development of economy in recent two decades, neonatology has been progressing quickly in China. However, there is little knowledge about the exact developmental status of neonatal departments i...

    Authors: Qiuping Li, Tao Han, Yanping Zhang, Qian Zhang, Xiangyong Kong, Yonghui Yang and Zhichun Feng

    Citation: BMC Pediatrics 2019 19:436

    Content type: Research article

    Published on:

  30. Identification of early signs of hypoxic ischemic encephalopathy (HIE) with magnetic resonance imaging (MRI) has proven of prognostic significance. Yet, the importance of intracranial hemorrhage (ICH), being p...

    Authors: Andrea Lakatos, Márton Kolossváry, Miklós Szabó, Ágnes Jermendy, Hajnalka Barta, Gyula Gyebnár, Gábor Rudas and Lajos R. Kozák

    Citation: BMC Pediatrics 2019 19:430

    Content type: Research article

    Published on:

  31. To construct birth weight charts for the Chongqing municipality, China and to identify whether differences in birth weight exist across urban/rural populations, thereby warranting separate charts.

    Authors: Xue Zhao, Yinyin Xia, Hua Zhang, Philip N. Baker and Tom Norris

    Citation: BMC Pediatrics 2019 19:426

    Content type: Research article

    Published on:

  32. Premature preterm rupture of membranes (PPROM) is reported to be associated with high rates of neonatal mortality and morbidity. Sildenafil has been used in infants with persistent pulmonary hypertension of ne...

    Authors: Karen Lavie-Nevo, Kevin C. Harris and Joseph Y. Ting

    Citation: BMC Pediatrics 2019 19:416

    Content type: Case report

    Published on:

  34. The factors that determine the effect of enteral feeding on intestinal perfusion after preterm birth remain largely unknown. We aimed to determine the effect of enteral feeding on intestinal oxygen saturation (ri...

    Authors: Sara J. Kuik, Anne G. J. F. van Zoonen, Arend F. Bos, Koenraad N. J. A. Van Braeckel, Jan B. F. Hulscher and Elisabeth M. W. Kooi

    Citation: BMC Pediatrics 2019 19:404

    Content type: Research article

    Published on:

  36. Previous studies showed that parents of very preterm infants expressed feelings of incompetence and experienced high levels of stress upon the discharge of their infants. We conducted a systematic review of se...

    Authors: S. Y. Lee, J. P. C. Chau, K. C. Choi and S. H. S. Lo

    Citation: BMC Pediatrics 2019 19:402

    Content type: Research article

    Published on:

  37. Thyroid hormones are critical for growth and brain development during the newborn period and infancy. Because of delayed maturation of the hypothalamic-pituitary-thyroid axis in preterm infants, thyroid dysfun...

    Authors: Hye-Rim Kim, Young Hwa Jung, Chang Won Choi, Hye Rim Chung, Min-Jae Kang and Beyong Il Kim

    Citation: BMC Pediatrics 2019 19:391

    Content type: Research article

    Published on:

  38. Nasal continuous positive airway pressure (CPAP) is widely used in the treatment and prevention of respiratory distress in preterm neonates, with only few severe adverse skin effects reported.

    Authors: P. Zachhau, A. E. Gravergaard and H. T. Christesen

    Citation: BMC Pediatrics 2019 19:383

    Content type: Case report

    Published on:

  39. Newborn screening (NBS) for cystic fibrosis (CF) not only identifies infants with a diagnosis of CF, but also those with an uncertain diagnosis of cystic fibrosis (CF), i.e. CF transmembrane conductance regula...

    Authors: Chee Y. Ooi, Rosie Sutherland, Carlo Castellani, Katherine Keenan, Margaret Boland, Joe Reisman, Candice Bjornson, Mark A. Chilvers, Richard van Wylick, Steven Kent, April Price, Dimas Mateos-Corral, Daniel Hughes, Melinda Solomon, Peter Zuberbuhler, Janna Brusky…

    Citation: BMC Pediatrics 2019 19:369

    Content type: Research article

    Published on:

  41. Most extremely low gestational age neonates (ELGANS, postmenstrual age at birth (PMA) < 28 completed weeks) require supplemental oxygen and experience frequent intermittent hypoxemic and hyperoxemic episodes. ...

    Authors: Christian A. Maiwald, Hendrik J. Niemarkt, Christian F. Poets, Michael S. Urschitz, Jochem König, Helmut Hummler, Dirk Bassler, Corinna Engel and Axel R. Franz

    Citation: BMC Pediatrics 2019 19:363

    Content type: Study protocol

    Published on:

  42. In Reunion Island, a French overseas department, the burden of preterm birth and perinatal mortality exceed those observed in mainland France, despite similar access to standard perinatal care. The purpose of ...

    Authors: Anais Godeluck, Patrick Gérardin, Victorine Lenclume, Corinne Mussard, Pierre-Yves Robillard, Sylvain Sampériz, Valérie Benhammou, Patrick Truffert, Pierre-Yves Ancel and Duksha Ramful

    Citation: BMC Pediatrics 2019 19:360

    Content type: Research article

    Published on:

  43. Incontinentia Pigmenti is a rare disease affecting multiple organs. Fifty of patients show affection of the eye with retinopathy and possible amaurosis being the worst outcome. Treatment has commonly been panr...

    Authors: S. Kunzmann, T. Ngyuen, A. Stahl, J. M. Walz, M. M. Nentwich, C. P. Speer and K. Ruf

    Citation: BMC Pediatrics 2019 19:353

    Content type: Case report

    Published on:

  45. Although over the years a number of studies have used chest circumference (CC) as a sensitive tool to identify the health status of infants, a particularly important aspect for this population is the lack of d...

    Authors: Ingrid G. Azevedo, Norrara S. O. Holanda, Nivia M. R. Arrais, Raweny T. G. Santos, Ana G. F. Araujo and Silvana A. Pereira

    Citation: BMC Pediatrics 2019 19:341

    Content type: Research article

    Published on:

  46. Patent ductus arteriosus (PDA), the most commonly diagnosed cardiovascular condition in preterm infants, is associated with increased mortality and harmful long-term outcomes (chronic lung disease, neurodevelo...

    Authors: Jonathan L. Slaughter, Clifford L. Cua, Jennifer L. Notestine, Brian K. Rivera, Laura Marzec, Erinn M. Hade, Nathalie L. Maitre, Mark A. Klebanoff, Megan Ilgenfritz, Vi T. Le, Dennis J. Lewandowski and Carl H. Backes

    Citation: BMC Pediatrics 2019 19:333

    Content type: Study protocol

    Published on:

  47. Most studies have revealed that the incidence of morbidity and mortality of preterm male infants is greater than that of preterm female infants. Recently, conflicting outcomes have been reported regarding mixe...

    Authors: Bernard Barzilay, Nina Shirman, Haim Bibi and Ibrahim Abu-Kishk

    Citation: BMC Pediatrics 2019 19:328

    Content type: Research article

    Published on:

  48. Although aminoglycosides are routinely used in neonates, controversy exists regarding empiric dosing regimens. The objectives were to determine gentamicin pharmacokinetics in neonates, and develop initial mg/k...

    Authors: Monique Bergenwall, Sandra A. N. Walker, Marion Elligsen, Dolores C. Iaboni, Carla Findlater, Winnie Seto and Eugene Ng

    Citation: BMC Pediatrics 2019 19:318

    Content type: Research article

    Published on:

  49. Complications of prematurity are the leading cause of deaths in children under the age of five. The predominant reason for these preterm deaths is respiratory distress syndrome (RDS). In low-income countries (...

    Authors: F. Okello, E. Egiru, J. Ikiror, L. Acom, KSM Loe, P. Olupot-Olupot and K. Burgoine

    Citation: BMC Pediatrics 2019 19:311

    Content type: Research article

    Published on:

  50. Various types of noninvasive respiratory modalities that lead to successful extubation in preterm infants have been explored. We aimed to compare noninvasive neurally adjusted ventilatory assist (NIV-NAVA) and...

    Authors: Byoung Kook Lee, Seung Han Shin, Young Hwa Jung, Ee-Kyung Kim and Han-Suk Kim

    Citation: BMC Pediatrics 2019 19:298

    Content type: Research article

    Published on:

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