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Neonatology

Section edited by Elizabeth Asztalos

This section considers studies regarding all aspects of neonatal health, disease, care, and outcomes.

Page 1 of 8

  1. Neonatal hypothermia is a global health problem and a major factor for neonatal morbidity and mortality, especially in low and middle-income countries. Therefore, this systematic review and meta-analysis aimed...

    Authors: Biruk Beletew, Ayelign Mengesha, Mesfin Wudu and Melese Abate

    Citation: BMC Pediatrics 2020 20:148

    Content type: Research article

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  2. Lung recruitment at birth has been advocated as an effective method of improving the respiratory transition at birth. Sustained inflations (SI) and dynamic positive end-expiratory pressure (PEEP) were assessed...

    Authors: Zalfa Kanaan, Coralie Bloch-Queyrat, Marouane Boubaya, Vincent Lévy, Pascal Bolot and Paul Waszak

    Citation: BMC Pediatrics 2020 20:144

    Content type: Research article

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  3. The emerging use of video in neonatology units raises ethical and practical questions. This study aims to gain a better understanding of the suitability, limitations and constraints concerning the use of live ...

    Authors: Aude Le Bris, Nadia Mazille-Orfanos, Pauline Simonot, Maude Luherne, Cyril Flamant, Geraldine Gascoin, Gearóid ÓLaighin, Richard Harte and Patrick Pladys

    Citation: BMC Pediatrics 2020 20:143

    Content type: Research article

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  4. Globally, about 2.7 million neonates die annually and more than 99% of these deaths happened in developing countries. Although most neonatal deaths are preventable and attempts had been taken to tackle these d...

    Authors: Banchigizie Adane Mengistu, Ayenew Engida Yismaw, Zelalem Nigussie Azene and Muhabaw Shumye Mihret

    Citation: BMC Pediatrics 2020 20:142

    Content type: Research article

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  5. Bronchopulmonary dysplasia (BPD) is among the most severe chronic lung diseases and predominantly affects premature infants. There is a general understanding of BPD’s significant impact on the short-term outco...

    Authors: Sasha van Katwyk, Sajit Augustine, Bernard Thébaud and Kednapa Thavorn

    Citation: BMC Pediatrics 2020 20:136

    Content type: Research article

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  6. Despite different preventive strategies that have been implemented in different health institutions in the country, neonatal mortality and morbidity are still significantly increasing in Ethiopia. Perinatal as...

    Authors: Fikadu Waltengus Sendeku, Getnet Gedefaw Azeze and Selamawit Lake Fenta

    Citation: BMC Pediatrics 2020 20:135

    Content type: Research article

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  7. Birth asphyxia accounts for one-quarter newborn deaths. Providing quality care service of neonatal resuscitation reduces neonatal mortality. However, challenges to providing quality neonatal resuscitation are ...

    Authors: Haftom Gebrehiwot Weldearegay, Mulugeta Woldu Abrha, Esayas Haregot Hilawe, Brhane Ayele Gebrekidan and Araya Abrha Medhanyie

    Citation: BMC Pediatrics 2020 20:129

    Content type: Research article

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  8. Meconium peritonitis is defined as aseptic chemical inflammation caused by intrauterine bowel perforation. The underlying causes of bowel perforation include intestinal atresia, midgut volvulus, intussusceptio...

    Authors: Kyung Hee Park, Mi Hye Bae, Na Rae Lee, Young Mi Han, Shin-Yun Byun and Hae-Young Kim

    Citation: BMC Pediatrics 2020 20:106

    Content type: Case report

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  9. Robin sequence (RS) is characterized by mandibular micro- and retrognathia, glossoptosis, upper airway obstruction and optionally a cleft palate. With an incidence of 1:8000, it belongs to the so-called rare d...

    Authors: Silvia Müller-Hagedorn, Jörg Arand, Thilo Scholz, Christian F. Poets and Cornelia Wiechers

    Citation: BMC Pediatrics 2020 20:103

    Content type: Technical advance

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  10. Non-invasive monitoring of cerebral tissue oxygen saturation (rcSO2) during transition is of growing interest. Different near-infrared spectroscopy (NIRS) techniques have been developed to measure rcSO2. We compa...

    Authors: Tanja van Essen, Tom G. Goos, Liza van Ballegooijen, Gerhard Pichler, Berndt Urlesberger, Irwin K. M. Reiss and Rogier C. J. de Jonge

    Citation: BMC Pediatrics 2020 20:94

    Content type: Research article

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  11. Prematurity is the leading cause of mortality in children under 5 years of age globally and is also frequently associated with postnatal growth failure (PGF). Although most preterm births occur in low resource...

    Authors: Clare Nakubulwa, Victor Musiime, Flavia B. Namiiro, James K Tumwine, Christine Hongella, James Nyonyintono, Anna B. Hedstrom and Robert Opoka

    Citation: BMC Pediatrics 2020 20:86

    Content type: Research article

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  12. Clostridium perfringens forms part of the human gut microbiota and has been associated with life-threatening necrotising enterocolitis (NEC) in premature infants. Whether specific toxigenic strains are responsibl...

    Authors: Alexander G. Shaw, Emma Cornwell, Kathleen Sim, Hannah Thrower, Hannah Scott, Joseph C. S. Brown, Ronald A. Dixon and J. Simon Kroll

    Citation: BMC Pediatrics 2020 20:75

    Content type: Research article

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  13. Different charts are used to assess premature growth. The Fenton chart, based on prenatal growth, has been used in the neonates’ intensive care unit (NICU) of the Notre Dame des Secours University Hospital to ...

    Authors: Marie Samarani, Gianna Restom, Joelle Mardini, Georges Abi Fares, Souheil Hallit and Marie-Claude Fadous Khalife

    Citation: BMC Pediatrics 2020 20:74

    Content type: Research article

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  14. Neonatal mortality remains a serious global public health problem, but Sub-Saharan Africa (SSA), in particular, is largely affected. Current evidence on neonatal mortality is essential to inform programs and p...

    Authors: Animut Alebel, Fasil Wagnew, Pammla Petrucka, Cheru Tesema, Nurilign Abebe Moges, Daniel Bekele Ketema, lieltework Yismaw, Mamaru Wubale Melkamu, Yitbarek Tenaw Hibstie, Belisty Temesgen, Zebenay Workneh Bitew, Animen Ayehu Tadesse and Getiye Dejenu Kibret

    Citation: BMC Pediatrics 2020 20:72

    Content type: Research article

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  15. The first consensus standardised neonatal parenteral nutrition formulations were implemented in many neonatal units in Australia in 2012. The current update involving 49 units from Australia, New Zealand, Sing...

    Authors: Srinivas Bolisetty, David Osborn, Tim Schindler, John Sinn, Girish Deshpande, Chee Sing Wong, Susan E. Jacobs, Nilkant Phad, Pramod Pharande, Rodney Tobiansky, Melissa Luig, Amit Trivedi, Joanne Mcintosh, Eszter Josza, Gillian Opie, Lyn Downe…

    Citation: BMC Pediatrics 2020 20:59

    Content type: Correspondence

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  16. Neonatal sepsis is an invasive infection, usually bacterial, and often occurring during the neonatal period (0–28 days). Neonatal sepsis causes a high burden of morbidity and mortality in developing countries ...

    Authors: Amare Belachew and Tilahun Tewabe

    Citation: BMC Pediatrics 2020 20:55

    Content type: Research article

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  18. Improved neonatal care has resulted in increased survival rates among infants born after only 22 gestational weeks, but extremely preterm children still have an increased risk of neurodevelopmental delays, lea...

    Authors: Erika Baraldi, Mara Westling Allodi, Kristina Löwing, Ann-Charlotte Smedler, Björn Westrup and Ulrika Ådén

    Citation: BMC Pediatrics 2020 20:49

    Content type: Study protocol

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  19. In Canada alone, almost 3000 VLBW infants are born and treated annually with almost 1200 going onto death or survival with severe brain injury, chronic lung disorders, aggressive retinopathy of prematurity, la...

    Authors: Elizabeth V. Asztalos, Keith Barrington, Abhay Lodha, William Tarnow-Mordi and Andrew Martin

    Citation: BMC Pediatrics 2020 20:40

    Content type: Study protocol

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  20. The well-being of mothers of infants requiring Neonatal Intensive Care Unit (NICU) hospitalization may be affected by the architectural design of the unit. A few recent studies suggest there may be some drawba...

    Authors: Nancy Feeley, Stephanie Robins, Christine Genest, Robyn Stremler, Phyllis Zelkowitz and Lyne Charbonneau

    Citation: BMC Pediatrics 2020 20:38

    Content type: Research article

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  21. Neonatal seizures are difficult to diagnose and, when they are, tradition dictates first line treatment is phenobarbital. There is little data on how consultants diagnose neonatal seizures, choose when to trea...

    Authors: Lucy Gossling, James J. P. Alix, Theocharis Stavroulakis and Anthony R. Hart

    Citation: BMC Pediatrics 2020 20:36

    Content type: Research article

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  22. Adverse birth outcome which attributes to most perinatal deaths is an important indicator of child health and survival. Hence, this study aims to identify determinants of adverse birth outcome among mothers wh...

    Authors: Helen Tsehaye Hailemichael, Gurmesa Tura Debelew, Haileselasie Berhane Alema, Meresa Gebremedhin Weldu and Kebede Haile Misgina

    Citation: BMC Pediatrics 2020 20:10

    Content type: Research article

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  23. Perinatal decision-making affects outcomes for extremely preterm babies (22–26 weeks’ gestational age (GA)): more active units have improved survival without increased morbidity. We hypothesised such units may...

    Authors: Andrei Scott Morgan, Babak Khoshnood, Caroline Diguisto, Laurence Foix L’Helias, Laetitia Marchand-Martin, Monique Kaminski, Jennifer Zeitlin, Gérard Bréart, François Goffinet and Pierre-Yves Ancel

    Citation: BMC Pediatrics 2020 20:8

    Content type: Research Article

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  24. Natural vegetable oils are widely used for newborn massage in many low resource settings. Animal models indicated that sunflower seed oil (SSO) can accelerate skin barrier recovery following damage, while othe...

    Authors: Aimee Summers, Marty O. Visscher, Subarna K. Khatry, Jeevan B. Sherchand, Steven C. LeClerq, Joanne Katz, James M. Tielsch and Luke C. Mullany

    Citation: BMC Pediatrics 2019 19:512

    Content type: Research article

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  25. The neonatal period is the most vulnerable time for child survival. The declines in the neonatal mortality rate have been slower than the post-neonatal under-five mortality rate in the majority of countries. T...

    Authors: Abera Mersha, Agegnehu Bante and Shitaye Shibiru

    Citation: BMC Pediatrics 2019 19:499

    Content type: Research article

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  26. This study aims to investigate the application value of three-dimensional arterial spin labeling (3DASL) in investigating cerebral blood flow dynamics in full-term neonates.

    Authors: Jia-Ning Wang, Jia Li, Huai-Jun Liu, Xiao-Ping Yin, Huan Zhou, Ya-Ting Zheng, Na An, Si Liang and Zuo-Jun Geng

    Citation: BMC Pediatrics 2019 19:495

    Content type: Research article

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  28. Colon stenosis and acute appendicitis are rare diseases among premature babies. To the best of our knowledge, no study has identified both the conditions in preterm babies.

    Authors: Takuto Naito, Hiromu Teramen, Hiroaki Hayashi, Mai Takegawa, Haruko Sakamoto, Toshihide Shimada, Koichi Ohno and Misao Yoshii

    Citation: BMC Pediatrics 2019 19:492

    Content type: Case report

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  29. The objective of the study was to evaluate data on early-onset neonatal invasive infections in western Sweden for the period 1997–2017. To identify changes in incidence, etiology and mortality and compare to p...

    Authors: Margrét Johansson Gudjónsdóttir, Anders Elfvin, Elisabet Hentz, Ingegerd Adlerberth, Ingemar Tessin and Birger Trollfors

    Citation: BMC Pediatrics 2019 19:490

    Content type: Research article

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  30. There is increasing evidence that intrauterine environment and, consequently, growth in utero have both immediate and far-reaching consequences for health. Neonatal body composition might be a more sensitive m...

    Authors: Cornelia Wiechers, Sara Kirchhof, Christoph Maas, Christian F. Poets and Axel R. Franz

    Citation: BMC Pediatrics 2019 19:489

    Content type: Research article

    Published on:

    The Research article to this article has been published in BMC Pediatrics 2019 19:488

  31. During pregnancy, a variety of factors can influence fetal growth and development. Intrauterine growth may impact on later life and health. Neonatal body composition may be a more sensitive marker for the intr...

    Authors: Cornelia Wiechers, Sara Kirchhof, Lena Balles, Vanessa Avelina, Romy Weber, Christoph Maas, Jan Pauluschke-Fröhlich, Manfred Hallschmid, Hubert Preißl, Andreas Fritsche, Christian F. Poets and Axel R. Franz

    Citation: BMC Pediatrics 2019 19:488

    Content type: Research article

    Published on:

    The Research article to this article has been published in BMC Pediatrics 2019 19:489

  32. Nutritive sucking is a complex activity, the biomechanical components of which may vary in relation to respiratory phase, swallow-rate per minute, suck-swallow ratio, and swallow non-inspiratory flow (SNIF). Q...

    Authors: M. L. J. Lagarde, N. van Alfen, S. A. F. de Groot, A. C. H. Geurts and L. van den Engel-Hoek

    Citation: BMC Pediatrics 2019 19:477

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Pediatrics 2020 20:44

  33. Recent guidelines recommend a cranial ultrasound (CU) in neonates born at < 30 weeks gestation, admitted to the neonatal intensive care unit (NICU), or with a CU indication. Here, we addressed the need to exte...

    Authors: Judith Weise, Matthias Heckmann, Hagen Bahlmann, Till Ittermann, Heike Allenberg, Grzegorz Domanski and Anja Erika Lange

    Citation: BMC Pediatrics 2019 19:476

    Content type: Research article

    Published on:

  34. The purpose of this study was to examine differences in attitudes to feeding in neonates with Gastroschisis between clinical groups and to develop a standardized feeding protocol. Confusion, inconsistencies in...

    Authors: Donna Hobson, Kaye Spence, Amit Trivedi and Gordon Thomas

    Citation: BMC Pediatrics 2019 19:475

    Content type: Research article

    Published on:

  35. Family Centered Care (FCC) has been widely adopted as the framework for caring for infants in the Neonatal Intensive Care Unit (NICU) but it is not uniformly defined or practiced, making it difficult to determ...

    Authors: Linda S. Franck, Rebecca M. Kriz, Robin Bisgaard, Diana M. Cormier, Priscilla Joe, Pamela S. Miller, Jae H. Kim, Carol Lin and Yao Sun

    Citation: BMC Pediatrics 2019 19:469

    Content type: Study protocol

    Published on:

  36. This study aims to provide guidance for clinical work through analysis of the clinical characteristics, endoscopic and pathological manifestations, diagnosis, and treatment of an 18-day-old neonate with exfoli...

    Authors: Zu-Qin Yang, Jing-Yun Mai, Min-Li Zhu, Xiu-Man Xiao, Xiao-Xiao He, Shang-Qin Chen and Zhen-Lang Lin

    Citation: BMC Pediatrics 2019 19:464

    Content type: Case report

    Published on:

  37. Gaining a better understanding of the probability, timing and prediction of rehospitalisation amongst preterm babies could help improve outcomes. There is limited research addressing these topics amongst extre...

    Authors: Robert Anthony Reed, Andrei Scott Morgan, Jennifer Zeitlin, Pierre-Henri Jarreau, Héloïse Torchin, Véronique Pierrat, Pierre-Yves Ancel and Babak Khoshnood

    Citation: BMC Pediatrics 2019 19:451

    Content type: Research article

    Published on:

  38. Stress signals during sucking activity such as nasal flaring, head turning, and extraneous movements of the body have been attributed to incoordination of sucking, swallowing, and respiration (SSR) in prematur...

    Authors: You Gyoung Yi, Byung-Mo Oh, Seung Han Shin, Jin Yong Shin, Ee-Kyung Kim and Hyung-Ik Shin

    Citation: BMC Pediatrics 2019 19:440

    Content type: Research article

    Published on:

  39. With the rapid development of economy in recent two decades, neonatology has been progressing quickly in China. However, there is little knowledge about the exact developmental status of neonatal departments i...

    Authors: Qiuping Li, Tao Han, Yanping Zhang, Qian Zhang, Xiangyong Kong, Yonghui Yang and Zhichun Feng

    Citation: BMC Pediatrics 2019 19:436

    Content type: Research article

    Published on:

  40. Identification of early signs of hypoxic ischemic encephalopathy (HIE) with magnetic resonance imaging (MRI) has proven of prognostic significance. Yet, the importance of intracranial hemorrhage (ICH), being p...

    Authors: Andrea Lakatos, Márton Kolossváry, Miklós Szabó, Ágnes Jermendy, Hajnalka Barta, Gyula Gyebnár, Gábor Rudas and Lajos R. Kozák

    Citation: BMC Pediatrics 2019 19:430

    Content type: Research article

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  41. To construct birth weight charts for the Chongqing municipality, China and to identify whether differences in birth weight exist across urban/rural populations, thereby warranting separate charts.

    Authors: Xue Zhao, Yinyin Xia, Hua Zhang, Philip N. Baker and Tom Norris

    Citation: BMC Pediatrics 2019 19:426

    Content type: Research article

    Published on:

  42. Premature preterm rupture of membranes (PPROM) is reported to be associated with high rates of neonatal mortality and morbidity. Sildenafil has been used in infants with persistent pulmonary hypertension of ne...

    Authors: Karen Lavie-Nevo, Kevin C. Harris and Joseph Y. Ting

    Citation: BMC Pediatrics 2019 19:416

    Content type: Case report

    Published on:

  44. The factors that determine the effect of enteral feeding on intestinal perfusion after preterm birth remain largely unknown. We aimed to determine the effect of enteral feeding on intestinal oxygen saturation (ri...

    Authors: Sara J. Kuik, Anne G. J. F. van Zoonen, Arend F. Bos, Koenraad N. J. A. Van Braeckel, Jan B. F. Hulscher and Elisabeth M. W. Kooi

    Citation: BMC Pediatrics 2019 19:404

    Content type: Research article

    Published on:

  46. Previous studies showed that parents of very preterm infants expressed feelings of incompetence and experienced high levels of stress upon the discharge of their infants. We conducted a systematic review of se...

    Authors: S. Y. Lee, J. P. C. Chau, K. C. Choi and S. H. S. Lo

    Citation: BMC Pediatrics 2019 19:402

    Content type: Research article

    Published on:

  47. Thyroid hormones are critical for growth and brain development during the newborn period and infancy. Because of delayed maturation of the hypothalamic-pituitary-thyroid axis in preterm infants, thyroid dysfun...

    Authors: Hye-Rim Kim, Young Hwa Jung, Chang Won Choi, Hye Rim Chung, Min-Jae Kang and Beyong Il Kim

    Citation: BMC Pediatrics 2019 19:391

    Content type: Research article

    Published on:

  48. Nasal continuous positive airway pressure (CPAP) is widely used in the treatment and prevention of respiratory distress in preterm neonates, with only few severe adverse skin effects reported.

    Authors: P. Zachhau, A. E. Gravergaard and H. T. Christesen

    Citation: BMC Pediatrics 2019 19:383

    Content type: Case report

    Published on:

  49. Newborn screening (NBS) for cystic fibrosis (CF) not only identifies infants with a diagnosis of CF, but also those with an uncertain diagnosis of cystic fibrosis (CF), i.e. CF transmembrane conductance regula...

    Authors: Chee Y. Ooi, Rosie Sutherland, Carlo Castellani, Katherine Keenan, Margaret Boland, Joe Reisman, Candice Bjornson, Mark A. Chilvers, Richard van Wylick, Steven Kent, April Price, Dimas Mateos-Corral, Daniel Hughes, Melinda Solomon, Peter Zuberbuhler, Janna Brusky…

    Citation: BMC Pediatrics 2019 19:369

    Content type: Research article

    Published on:

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