Skip to main content

Infection

This section considers studies regarding the epidemiology, pathology, prevention, and control of infectious diseases in children and adolescents.

Page 4 of 5

  1. Acute lower respiratory tract infection is the commonest disease affecting children under five worldwide. Respiratory syncytial virus (RSV) is among the most common causative pathogens. Epidemiological data su...

    Authors: Magdeldin Elgizouli, Chad Logan, Ruth Grychtol, Dietrich Rothenbacher, Alexandra Nieters and Andrea Heinzmann

    Citation: BMC Pediatrics 2017 17:65

    Content type: Research article

    Published on:

  2. RotaTeq™ (RV5; Merck & Co. Inc., USA) and Rotarix™ (RV1, GlaxoSmithKline, Belgium) vaccines, developed to prevent rotavirus diarrhea in children under five years old, were both introdu...

    Authors: Raúl F. Velázquez, Alexandre C. Linhares, Sergio Muñoz, Pamela Seron, Pedro Lorca, Rodrigo DeAntonio and Eduardo Ortega-Barria

    Citation: BMC Pediatrics 2017 17:14

    Content type: Research article

    Published on:

  3. Progress has been made in tackling malaria however there are still over 207 million cases worldwide, the majority in children. As survival rates improve, numbers of children with long-term neurodisabling seque...

    Authors: Emmie W. Mbale, Terrie Taylor, Bernard Brabin, Macpherson Mallewa and Melissa Gladstone

    Citation: BMC Pediatrics 2017 17:9

    Content type: Research article

    Published on:

  4. Chronic otitis media with effusion (COME) is a prevalent upper airway infection resulting in hearing loss. The aim of this research was to determine risk factors for COME in preschool children.

    Authors: Rebecca E. Walker, Jim Bartley, David Flint, John M. D. Thompson and Edwin A. Mitchell

    Citation: BMC Pediatrics 2017 17:4

    Content type: Research article

    Published on:

  5. Central retinal artery occlusion (CRAO) is an arterial ischemic stroke, rarely occurred in children accompanied with asymptomatic cerebral infarction and almost never involved in severe pneumonia related to My...

    Authors: Yunguang Bao, Xiaobing Li, Kaixuan Wang, Chan Zhao, Xiumei Ji and Mizu Jiang

    Citation: BMC Pediatrics 2016 16:210

    Content type: Case report

    Published on:

  6. Despite differences in types of infection and causative organisms, pharmacokinetic-pharmacodynamic (PKPD) targets of vancomycin therapy derived from adult studies are suggested for neonates. We aimed to identi...

    Authors: Helgi Padari, Kersti Oselin, Tõnis Tasa, Tuuli Metsvaht, Krista Lõivukene and Irja Lutsar

    Citation: BMC Pediatrics 2016 16:206

    Content type: Research article

    Published on:

  7. Qualitative and quantitative research investigating determinants of adherence to clinical guidelines (GLs) on surgical antibiotic prophylaxis (SAP) are scarce. We conducted a mixed-method study aimed at invest...

    Authors: Angela Giusti, Stefania Spila Alegiani, Marta Luisa Ciofi degli Atti, Sofia Colaceci, Roberto Raschetti, Pasquale Arace, Raffaele Spiazzi and Massimiliano Raponi

    Citation: BMC Pediatrics 2016 16:203

    Content type: Research article

    Published on:

  8. Febrile seizures are common in young children. Annual peaks in incidence mirror increased respiratory virus activity during winter. Limited virological data are available using modern diagnostic techniques for...

    Authors: Joshua R. Francis, Peter Richmond, Christine Robins, Katie Lindsay, Avram Levy, Paul V. Effler, Meredith Borland and Christopher C. Blyth

    Citation: BMC Pediatrics 2016 16:202

    Content type: Research article

    Published on:

  9. In children, the most significant cause of rhabdomyolysis or muscle breakdown is viral infection. However, there are no reports that norovirus, a gastroenteric virus that commonly infects children, specificall...

    Authors: Tomohiro Nishio, Ryoko Yonetani, Eisuke Ito, Makiko Yoneta, Yoshihiro Maruo, Tokiko Yoshida and Tohru Sugimoto

    Citation: BMC Pediatrics 2016 16:176

    Content type: Case report

    Published on:

  10. Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hematological disorder associated with severe systemic inflammation caused by an uncontrolled and ineffective immune response resulting in cytokin...

    Authors: Yoshiki Kawamura, Hiroki Miura, Yuji Matsumoto, Hidetoshi Uchida, Kazuko Kudo, Tadayoshi Hata, Yoshinori Ito, Hiroshi Kimura and Tetsushi Yoshikawa

    Citation: BMC Pediatrics 2016 16:172

    Content type: Case report

    Published on:

  11. Norovirus (NoV) GII.4 is the most common genotype for norovirus gastroenteritis worldwide. New variants or subgenotypes are continuously emerging, thus posing a serious threat to child health.

    Authors: Pei-Lin Wang, Shih-Yen Chen, Chi-Neu Tsai, Hsun-Ching Chao, Ming-Wei Lai, Yi-Jung Chang, Chyi-Liang Chen and Cheng-Hsun Chiu

    Citation: BMC Pediatrics 2016 16:162

    Content type: Research article

    Published on:

  12. Nasal colonization with bacterial pathogens is associated with risk of invasive respiratory tract infections, but the related information for Chinese healthy children is scarce.

    Authors: Hui Pan, Binglin Cui, Yuanchun Huang, Jiacai Yang and William Ba-Thein

    Citation: BMC Pediatrics 2016 16:161

    Content type: Research article

    Published on:

  13. Wheezing is a common symptom in early childhood. However, refractory wheezing is difficult to treat, and it may thus account for extensive use of medical resources. It is therefore important to improve our und...

    Authors: Wenjing Gu, Wujun Jiang, Xinxing Zhang, Zhengrong Chen, Yongdong Yan, Li Huang, Meijuan Wang, Xuejun Shao, Shuhui Wang and Wei Ji

    Citation: BMC Pediatrics 2016 16:145

    Content type: Research article

    Published on:

  14. Lower respiratory tract infection is a common cause of consultation and antibiotic prescription in paediatric practice. The misuse of antibiotics is a major cause of the emergence of multidrug-resistant bacter...

    Authors: Elise Launay, Karine Levieux, Corinne Levy, François Dubos, Alain Martinot, Bénédicte Vrignaud, Flora Lepage, Robert Cohen, Emmanuel Grimprel, Matthieu Hanf, François Angoulvant and Christèle Gras-Le Guen

    Citation: BMC Pediatrics 2016 16:126

    Content type: Research article

    Published on:

  15. Little is known on outcomes after transition to adult care among adolescents with perinatal HIV infection. Though there is data from other chronic pediatric diseases suggesting increased morbidity and mortalit...

    Authors: Fatima Kakkar, Dimitri Van der Linden, Silvie Valois, Francois Maurice, Marion Onnorouille, Normand Lapointe, Hugo Soudeyns and Valerie Lamarre

    Citation: BMC Pediatrics 2016 16:109

    Content type: Research article

    Published on:

  16. The comparison of the frequencies of bacterial and viral infections among children with community-acquired pneumonia (CAP) admitted in distinct severity categories, in an original study, is lacking in literatu...

    Authors: Amanda C. Nascimento-Carvalho, Olli Ruuskanen and Cristiana M. Nascimento-Carvalho

    Citation: BMC Pediatrics 2016 16:105

    Content type: Research article

    Published on:

  17. Fluid bolus administration is widely recommended as part of the initial treatment of paediatric sepsis, though the physiological benefits and harms are unclear. The primary aim of this study is to determine th...

    Authors: Elliot Long, Ed Oakley, Franz E. Babl and Trevor Duke

    Citation: BMC Pediatrics 2016 16:93

    Content type: Study protocol

    Published on:

  18. While biomarkers for chronic fatigue syndrome (CFS) are beginning to emerge they typically require a highly specialized clinical laboratory. We hypothesized that subsets of commonly measured laboratory markers...

    Authors: Jeanna M. Harvey, Gordon Broderick, Alanna Bowie, Zachary M. Barnes, Ben Z. Katz, Maurice R. G. O’Gorman, Suzanne D. Vernon, Mary Ann Fletcher, Nancy G. Klimas and Renee Taylor

    Citation: BMC Pediatrics 2016 16:54

    Content type: Research article

    Published on:

  19. China is one of ten countries with the highest prevalence rate of pneumococcal infections. However, there is limited serotype surveillance data for Streptococcus pneumoniae, especially from the community or rural...

    Authors: Ping Jin, Lijuan Wu, Shahin Oftadeh, Timothy Kudinha, Fanrong Kong and Qiyi Zeng

    Citation: BMC Pediatrics 2016 16:53

    Content type: Research article

    Published on:

  20. The paediatric Human Immunodeficiency Virus (HIV) epidemic still progresses because of operational challenges in implementing prevention of mother-to-child HIV transmission (PMCT) programs. We assessed the kno...

    Authors: Malik Coulibaly, Elisabeth Thio, Caroline Yonaba, Sylvie Ouédraogo, Nicolas Meda, Fla Kouéta, Désiré Lucien Dahourou, Angèle Kalmogho, Mady Gansonré, Diarra Yé, Ludovic Kam and Valériane Leroy

    Citation: BMC Pediatrics 2016 16:33

    Content type: Research article

    Published on:

  21. GSK’s varicella vaccine contains human serum albumin (HSA) which is used to stabilize the virus and prevent immunogens from adhering to the injection vial walls. However, because HSA is derived from human bloo...

    Authors: Roman Prymula, Robert Simko, Michael Povey and Andrea Kulcsar

    Citation: BMC Pediatrics 2016 16:7

    Content type: Research article

    Published on:

  22. Early childhood environmental exposures, possibly infections, may be responsible for triggering islet autoimmunity and progression to type 1 diabetes (T1D). The Environmental Determinants of Diabetes in the Yo...

    Authors: Maria Lönnrot, Kristian Lynch, Helena Elding Larsson, Åke Lernmark, Marian Rewers, William Hagopian, Jin-Xiong She, Olli Simell, Anette-G Ziegler, Beena Akolkar, Jeffrey Krischer and Heikki Hyöty

    Citation: BMC Pediatrics 2015 15:24

    Content type: Research article

    Published on:

  23. Adherence to an antiretroviral regimen is imperative for treatment success in both HIV infected adults and children. Likewise, adherence to antiretroviral prophylaxis is critical in HIV prevention. Studies on ...

    Authors: Alicia Catherine Desmond, Dhayendre Moodley, Catherine A Conolly, Sandra A Castel and Hoosen M Coovadia

    Citation: BMC Pediatrics 2015 15:23

    Content type: Research article

    Published on:

  24. Despite expanded programs for prevention of mother-to-child HIV transmission (PMTCT), HIV-infected infants may not be diagnosed until they are ill. Comparing HIV prevalence and outcomes in infants diagnosed in...

    Authors: Anjuli Wagner, Jennifer Slyker, Agnes Langat, Irene Inwani, Judith Adhiambo, Sarah Benki-Nugent, Ken Tapia, Irene Njuguna, Dalton Wamalwa and Grace John-Stewart

    Citation: BMC Pediatrics 2015 15:10

    Content type: Research article

    Published on:

  25. This study aimed to determine the clinical efficacy of various immune interventions on mother-to-child transmission (MTCT) of hepatitis B virus (HBV).

    Authors: Hui Jin, Yueyuan Zhao, Zhaoying Tan, Xuefeng Zhang, Yaoyun Zhao, Bei Wang and Pei Liu

    Citation: BMC Pediatrics 2014 14:307

    Content type: Research article

    Published on:

  26. The relative incidence and clinical impact of individual respiratory viruses remains unclear among children presenting to the hospital emergency department with acute respiratory tract infection (ARTI).

    Authors: Jairo Gooskens, Vishnu van der Ploeg, Ram N Sukhai, Ann CTM Vossen, Eric CJ Claas and Aloys CM Kroes

    Citation: BMC Pediatrics 2014 14:297

    Content type: Research article

    Published on:

  27. Infection with respiratory syncytial virus (RSV) is common among young children insured through Medicaid in the United States. Complete and timely dosing with palivizumab is associated with lower risk of RSV-r...

    Authors: Leonard R Krilov, Anthony S Masaquel, Leonard B Weiner, David M Smith, Sally W Wade and Parthiv J Mahadevia

    Citation: BMC Pediatrics 2014 14:261

    Content type: Research article

    Published on:

  28. Parents’ knowledge about immunization is an important predictor factor for their children’s immunization status. The aims of this study were to assess parents’ knowledge and to evaluate the effect of a short e...

    Authors: Ammar Ihsan Awadh, Mohamed Azmi Hassali, Omer Qutaiba Al-lela, Siti Halimah Bux, Ramadan M Elkalmi and Hazrina Hadi

    Citation: BMC Pediatrics 2014 14:254

    Content type: Research article

    Published on:

  29. Children under 5 represent 86% of annual malaria deaths in the world. Following increasing trends in international travel, cases of imported malaria are rising in North America. We describe the epidemiology of...

    Authors: Andrea B Evans, Dina Kulik, Anna Banerji, Andrea Boggild, Kevin C Kain, Mohamed Abdelhaleem and Shaun K Morris

    Citation: BMC Pediatrics 2014 14:251

    Content type: Research article

    Published on:

  30. The Ethiopian epidemic is currently on the wane. However, the situation for infected children is in some ways lagging behind due to low treatment coverage and deficient prevention of mother-to-child transmissi...

    Authors: Emil Westerlund, Degu Jerene, Zewdie Mulissa, Inger Hallström and Bernt Lindtjørn

    Citation: BMC Pediatrics 2014 14:250

    Content type: Research article

    Published on:

  31. Despite huge public campaigns, there is still overconsumption of antibiotics in children with self-limiting diseases. Possible explanations may be the physicians’ and parents’ uncertainty about the gravity of ...

    Authors: Marieke B Lemiengre, Jan Y Verbakel, Tine De Burghgraeve, Bert Aertgeerts, Frans De Baets, Frank Buntinx and An De Sutter

    Citation: BMC Pediatrics 2014 14:246

    Content type: Study protocol

    Published on:

  32. Acute illness is the most common presentation of children to ambulatory care. In contrast, serious infections are rare and often present at an early stage. To avoid complications or death, early recognition an...

    Authors: Jan Y Verbakel, Marieke B Lemiengre, Tine De Burghgraeve, An De Sutter, Dominique M A Bullens, Bert Aertgeerts and Frank Buntinx

    Citation: BMC Pediatrics 2014 14:207

    Content type: Study protocol

    Published on:

  33. To determine the serotypes of Streptococcus pneumoniae responsible for pneumonia complicated by parapneumonic effusion in children, we performed real-time PCR based pneumococcal “serotyping” directly on parapneum...

    Authors: Robert Slinger, Lucie Hyde, Ioana Moldovan, Francis Chan and Jeffrey M Pernica

    Citation: BMC Pediatrics 2014 14:189

    Content type: Research article

    Published on:

  34. To describe the utilisation of antibiotics in children and adolescents across 5 European countries based on the same drug utilisation measures and age groups. Special attention was given to age-group-specific ...

    Authors: Jakob Holstiege, Tania Schink, Mariam Molokhia, Giampiero Mazzaglia, Francesco Innocenti, Alessandro Oteri, Irene Bezemer, Elisabetta Poluzzi, Aurora Puccini, Sinna Pilgaard Ulrichsen, Miriam C Sturkenboom, Gianluca Trifirò and Edeltraut Garbe

    Citation: BMC Pediatrics 2014 14:174

    Content type: Research article

    Published on:

  35. Streptococcus pneumoniae (S. pneumoniae) and Haemophilus influenzae (H. influenzae) are considered major causes of bacterial acute otitis media (AOM) worldwide, but data from Asia on primary causes of AOM are li...

    Authors: Pavinee Intakorn, Nuntigar Sonsuwan, Suwiwan Noknu, Greetha Moungthong, Jean-Yves Pirçon, Yanfang Liu, Melissa K Van Dyke and William P Hausdorff

    Citation: BMC Pediatrics 2014 14:157

    Content type: Research article

    Published on:

  36. Cerebral venous sinus thrombosis (CVT) is a rare and potentially life-threatening condition in the pediatric population. The clinical presentation is frequently nonspecific; thus diagnosis is often delayed or ...

    Authors: Elena Bozzola, Mauro Bozzola, Giovanna Stefania Colafati, Valeria Calcaterra, Annachiara Vittucci, Matteo Luciani and Alberto Villani

    Citation: BMC Pediatrics 2014 14:147

    Content type: Case report

    Published on:

  37. Acute lower respiratory infections (ALRIs) are leading causes of hospitalisation in children. Birth defects occur in 5% of live births in Western Australia (WA). The association between birth defects and ALRI ...

    Authors: Khadra A Jama-Alol, Hannah C Moore, Peter Jacoby, Carol Bower and Deborah Lehmann

    Citation: BMC Pediatrics 2014 14:80

    Content type: Research article

    Published on:

  38. While studies of HIV-infected adults on antiretroviral treatment (ART) report no sex differences in immune recovery and virologic response but more ART-associated complications in women, sex differences in dis...

    Authors: Stephanie Shiau, Louise Kuhn, Renate Strehlau, Leigh Martens, Helen McIlleron, Sandra Meredith, Lubbe Wiesner, Ashraf Coovadia, Elaine J Abrams and Stephen M Arpadi

    Citation: BMC Pediatrics 2014 14:39

    Content type: Research article

    Published on:

  39. Clostridium difficile infection (CDI) is the most common cause of health care–associated diarrhea in children and adults. Although serious complications of CDI have been reported to be increasing in adults, this...

    Authors: Kevin L Schwartz, Ilyse Darwish, Susan E Richardson, Michael R Mulvey and Nisha Thampi

    Citation: BMC Pediatrics 2014 14:28

    Content type: Research article

    Published on:

  40. Erythema infectiosum is the most common clinical manifestation of Parvovirus B19 infection although it has also been associated with rheumatologic diseases and various types of systemic vasculitides. Acute hep...

    Authors: Maria Koliou, Evaggelia Karaoli, Elpidoforos S Soteriades, Sylvie Pavlides, Stavros Bashiardes and Christina Christodoulou

    Citation: BMC Pediatrics 2014 14:6

    Content type: Case report

    Published on:

  41. In the United States, influenza vaccination is recommended for all children 6 months and older; however, vaccination rates are below target levels. A broad sample of U.S. pediatric offices was assessed to dete...

    Authors: Chyongchiou Jeng Lin, Mary Patricia Nowalk, Seth L Toback and Christopher S Ambrose

    Citation: BMC Pediatrics 2013 13:180

    Content type: Research article

    Published on:

  42. In two clinical trials, low-grade fever was observed more frequently after coadministration than after separate administration of two recommended routine pediatric vaccines. Since fever is an important issue w...

    Authors: Markus A Rose, Christine Juergens, Beate Schmoele-Thoma, William C Gruber, Sherryl Baker and Stefan Zielen

    Citation: BMC Pediatrics 2013 13:98

    Content type: Research article

    Published on:

  43. Adherence to antiretroviral drugs in the treatment of paediatric HIV infection is complicated because of many factors including stigma and drug intake logistics. It is therefore important to identify children ...

    Authors: Frida William Mghamba, Omary MS Minzi, Augustine Massawe and Philip Sasi

    Citation: BMC Pediatrics 2013 13:95

    Content type: Research article

    Published on:

  44. Rates of laboratory testing and diagnostic practices for congenital CMV in the United States are unknown. We determined rates of CMV testing and diagnostic coding for CMV among insured infants in the United St...

    Authors: Jessica Leung, Michael J Cannon, Scott D Grosse and Stephanie R Bialek

    Citation: BMC Pediatrics 2013 13:90

    Content type: Research article

    Published on:

  45. Rotavirus is a leading worldwide cause of acute gastroenteritis in young children. This retrospective hospital-based study assessed the burden of rotavirus gastroenteritis in children younger than 6 years in J...

    Authors: Hitoshi Tajiri, Yuriko Takeuchi, Tomoko Takano, Toshihiro Ohura, Ayano Inui, Kimie Yamamoto, Yoshihito Higashidate, Hisashi Kawashima, Shigeru Toyoda, Kosuke Ushijima, Gunasekaran Ramakrishnan, Mats Rosenlund and Katsiaryna Holl

    Citation: BMC Pediatrics 2013 13:83

    Content type: Research article

    Published on: