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General pediatric medicine and surgery

This section considers studies of general medicine and surgical intervention in children and adolescents.

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  1. Children with acute peripheral facial nerve palsy cannot yet be recommended corticosteroid treatment based on evidence. Adults with idiopathic facial nerve palsy are treated with corticosteroids, according to ...

    Authors: Sofia Karlsson, Sigurdur Arnason, Nermin Hadziosmanovic, Åsa Laestadius, Malou Hultcrantz, Elin Marsk and Barbro H. Skogman

    Citation: BMC Pediatrics 2021 21:220

    Content type: Study protocol

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  2. Ewing’s sarcoma is a common malignant bone tumor in children and young adults. Rarely, extra-skeletal soft tissues and visceral organs can also be the site of origin of Ewing’s sarcoma. Primary pulmonary Ewing...

    Authors: Xuefeng Ling, Jianlin Tong, Liangliang Wang, Chuan Yao and Zhiying Chen

    Citation: BMC Pediatrics 2021 21:194

    Content type: Case report

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  3. HIV is a major contributor to infant mortality. A significant gap remains between the uptake of infant and maternal antiretroviral regimens and only a minority of HIV-exposed infants receives prophylaxis and s...

    Authors: Lilian M. N. Kebaya, Dalton Wamalwa, Nyambura Kariuki, Bashir Admani, Philip Ayieko and Ruth Nduati

    Citation: BMC Pediatrics 2021 21:186

    Content type: Research article

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  4. Characteristics of obstructive sleep apnea (OSA) changes with age. Infants, toddlers and prepubertal children with OSA are usually underweight and may suffer from failure to thrive (FTT). Adenotonsillectomy (T...

    Authors: Keren Nathan, Galit Livnat, Liat Feraru and Giora Pillar

    Citation: BMC Pediatrics 2021 21:184

    Content type: Research article

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  5. The aim of this study was to characterize patients who ingested multiple rare-earth magnets, reveal the harm of rare-earth magnet foreign bodies in the digestive tract, and develop a clinical management algori...

    Authors: Yucan Zheng, Zhihua Zhang, Kunlong Yan, Hongmei Guo, Mei Li, Min Lian and Zhifeng Liu

    Citation: BMC Pediatrics 2021 21:179

    Content type: Research article

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  6. Dental procedures under general anesthesia (DGA) was found to improve the oral health-related quality of children’s life. However, some parents and pediatricians expressed concern about the neurotoxicity of ge...

    Authors: Pinping Zhou, Chao Zhang, Guijin Huang, Yuan Hu, Wenzhu Ma and Cong Yu

    Citation: BMC Pediatrics 2021 21:177

    Content type: Research article

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  7. The aim of the present study was to summarize the clinical characteristics of in children aged under 3 years and analyze the related factors affecting the prognosis.

    Authors: Tian Zhi, Wei-Ling Zhang, Yi Zhang, Hui-Min Hu and Dong-Sheng Huang

    Citation: BMC Pediatrics 2021 21:170

    Content type: Research article

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  8. Homelessness is associated with health problems and with adverse childhood experiences (ACEs). The risk of chronic health conditions for homeless compared to housed youth, and how this risk interacts with ACEs...

    Authors: Andrew J. Barnes, Amy L. Gower, Mollika Sajady and Katherine A. Lingras

    Citation: BMC Pediatrics 2021 21:164

    Content type: Research article

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  9. Lipoblastoma is a rare benign mesenchymal neoplasm of infancy that most commonly occurs on the extremities and trunk but can arise at variable sites of the body. Retroperitoneal lipoblastomas are particularly ...

    Authors: Elena Gerhard-Hartmann, Verena Wiegering, Clemens Benoit, Thomas Meyer, Andreas Rosenwald, Katja Maurus and Karen Ernestus

    Citation: BMC Pediatrics 2021 21:159

    Content type: Case report

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  10. Kawasaki disease (KD) is a form of systemic febrile vasculitis that is complicated with coronary artery lesions (CAL). The tight junctions that maintain the intestinal barrier also play a role in systemic infl...

    Authors: Wan-Tz Lai, Hung-Chang Lee, Ying-Hsien Huang, Mao-Hung Lo and Ho-Chang Kuo

    Citation: BMC Pediatrics 2021 21:157

    Content type: Research article

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  11. Necrotizing enterocolitis (NEC) is a common devastating inflammatory gastrointestinal disease and frequently occurs in premature infants. Here, we reported a case of late-onset NEC in a term neonate with good ...

    Authors: Gunadi, Dian Nirmala Sirait, Aditya Rifqi Fauzi, Ninditya Nugroho, Fadil Fahri, William Widitjiarso, Kristy Iskandar and Nurnaningsih

    Citation: BMC Pediatrics 2021 21:152

    Content type: Case report

    Published on:

  12. In the current study, we applied a combination of non-invasive neuromodulation modalities concurrently with multiple stimulating electrodes. Specifically, we used transcranial pulsed current stimulation (tPCS)...

    Authors: Zhenhuan Liu, Shangsheng Dong, Sandra Zhong, Fang Huang, Chuntao Zhang, Yuan Zhou and Haorong Deng

    Citation: BMC Pediatrics 2021 21:141

    Content type: Research article

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  13. Using effective scolicidal agents intraoperatively is essential to lessen the recurrence rate of hepatic echinococcosis. However, severe hypernatremia may occur after hypertonic saline (HS) has been applied as...

    Authors: Kewei Li, Yijun Liu, Xiaolong Xie, Rongxing Zhou and Bo Xiang

    Citation: BMC Pediatrics 2021 21:140

    Content type: Research article

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  14. Malignant melanoma (MM) arises predominantly after adolescence and is uncommon in children. Congenital MM in newborns is even rarer with a dearth of published literature; as a consequence, there is no uniform ...

    Authors: Jun Zhou, Meng-xing Lv, Ling Duan, Yu-cheng Xie, Zhi-xiang A, Hong-fang Wu and Yan Gao

    Citation: BMC Pediatrics 2021 21:121

    Content type: Case report

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  15. Defects of bone marrow mesenchymal stem cells (BM-MSCs) in proliferation and differentiation are involved in the pathophysiology of aplastic anemia (AA). Infusion of umbilical cord mesenchymal stem cells (UC-M...

    Authors: Yang Lan, Fang Liu, Lixian Chang, Lipeng Liu, Yingchi Zhang, Meihui Yi, Yuli Cai, Jing Feng, Zhibo Han, Zhongchao Han and Xiaofan Zhu

    Citation: BMC Pediatrics 2021 21:102

    Content type: Research article

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  16. Cornell assessment of pediatric delirium (CAPD) showed advantage in diagnosis of pediatric delirium in Chinese critically ill patients. But its performance in surgical patients is still unclear. The present st...

    Authors: Hong Hong, Chao Guo, Zhi-Hua Liu, Bo-Jie Wang, Shu-Zhe Zhou, Dong-Liang Mu and Dong-Xin Wang

    Citation: BMC Pediatrics 2021 21:87

    Content type: Research article

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  17. As sleep-related difficulties are a growing public health concern, it is important to gain an overview of the specific difficulty areas of the most vulnerable individuals: children. The current descriptive stu...

    Authors: Christiane Lewien, Jon Genuneit, Christof Meigen, Wieland Kiess and Tanja Poulain

    Citation: BMC Pediatrics 2021 21:82

    Content type: Research article

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  18. Cognitive abilities like language, memory, reasoning, visualization, and perceptual functioning shape human action and are considered critical to the successful interaction with the environment. Alternatively,...

    Authors: Fidaa Almomani, Murad O. Al-momani, Soha Garadat, Safa Alqudah, Manal Kassab, Shereen Hamadneh, Grant Rauterkus and Richard Gans

    Citation: BMC Pediatrics 2021 21:71

    Content type: Research article

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  19. This study aimed to retrospectively analyze the correlation between congenital abnormality of the urogenital system and various factors in children with neural tube defects (NTDs).

    Authors: Zhi-Hua Hong, Dong-Hui Jin, Xiao-Jian Yuan, Yang Zhao, Hou-Wei Lin and Jie Chen

    Citation: BMC Pediatrics 2021 21:66

    Content type: Research article

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  20. For newborns and infants wearing diapers the difficulties in characterizing the appearance of the stool are significant, since the changes in consistency, quantity, and color of the stool are higher than in ot...

    Authors: Laura Cantisano de Deus Silva, Priscila Monaro Bianchini, Erika Veruska Paiva Ortolan, Juliana Fattori Hamamoto, Rosemary Fermiano, Rebeca Mayara Padilha Rego, João César Lyra, Marc Alexander Benninga and Pedro Luiz Toledo de Arruda Lourenção

    Citation: BMC Pediatrics 2021 21:64

    Content type: Research article

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  21. The effect of biologic therapy on the incidence of inflammatory bowel disease (IBD)-related hospitalizations is controversial. The high efficacy of biologic agents is weighted against potential therapy-related...

    Authors: Gil Berkovitch, Shlomi Cohen, Ronit Lubetzky, Dana Singer and Anat Yerushalmy-Feler

    Citation: BMC Pediatrics 2021 21:63

    Content type: Research article

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  22. Depression in children presents a significant health burden to society and often co-exists with chronic illnesses, such as human immunodeficiency virus (HIV). Research has demonstrated that 10–37% of children ...

    Authors: Agnes Binagwaho, Eric Remera, Alice Uwase Bayingana, Darius Gishoma, Kirstin Woody Scott, Madeline Goosman, Eliza Campbell, Mawuena Agbonyitor, Yvonne Kayiteshonga and Sabin Nsanzimana

    Citation: BMC Pediatrics 2021 21:59

    Content type: Research article

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  23. An Anorectal Malformation (ARM) is a rare congenital malformation, which requires proper correction to ensure the best long-term prognosis. These procedures are relatively infrequent and complex, in which a st...

    Authors: J. A. van Ling, G. M. J. Bökkerink, I. de Blaauw and S. M. B. I. Botden

    Citation: BMC Pediatrics 2021 21:57

    Content type: Technical advance

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  24. We aimed to study the effectiveness of preoperative thyroid hormone levels in predicting intensive care unit (ICU) mortality after cardiopulmonary bypass (CPB) in infants with congenital heart disease (CHD).

    Authors: Di Yu, Liang Zou, Yueshuang Cun, Yaping Li, Qingfeng Wang, Yaqin Shu and Xuming Mo

    Citation: BMC Pediatrics 2021 21:50

    Content type: Research article

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  25. The purpose of this study was to assess scan parameters and to propose strategies to optimize the examinations of children (from 0 to 15 years old) on adult scanners in developing countries.

    Authors: Fotso Eddy Kamdem, Samba Odette Ngano, Clemence Alla Takam, Alain Jervé Fotue, Serge Abogo and Cornellius Lukong Fai

    Citation: BMC Pediatrics 2021 21:44

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Pediatrics 2021 21:93

  26. Paediatric poisoning is a common presentation to emergency departments worldwide. There is a paucity of data on the role of liquid chromatography-tandem mass spectrometry (LC-MS/MS), in the management of paedi...

    Authors: Norbertta Washaya, Alicia Evans, Rudzani Muloiwa, Peter Smith and Heloise Buys

    Citation: BMC Pediatrics 2021 21:42

    Content type: Research article

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  27. Imerslund-Gräsbeck syndrome is a rare genetic disease characterised by vitamin B12 deficiency and proteinuria.

    Authors: Visvalingam Arunath, Thabitha Jebaseeli Hoole, Asanka Rathnasri, Oshanie Muthukumarana, Ishara Minuri Kumarasiri, Nishadi Dananjani Liyanage, Yasintha Costa and Sachith Mettananda

    Citation: BMC Pediatrics 2021 21:41

    Content type: Case report

    Published on:

  28. The last two decades brought new treatment options and high quality guidelines into the paediatric rheumatologic practice. Nevertheless, a number of patients still present a diagnostic and therapeutic challeng...

    Authors: Vana Vukić, Ana Smajo, Mandica Vidović, Rudolf Vukojević, Miroslav Harjaček and Lovro Lamot

    Citation: BMC Pediatrics 2021 21:40

    Content type: Case report

    Published on:

  29. Intestinal lymphangiectasia is a rare disease. Thus, prospective studies are impossible, and therapy is still controversial. Several medicines are suggested for treatment but there are no existing indications ...

    Authors: Yiyoung Kwon, Eun Sil Kim, Yon Ho Choe and Mi Jin Kim

    Citation: BMC Pediatrics 2021 21:21

    Content type: Research article

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  30. Upper endoscopy is an essential tool for diagnosing pediatric gastrointestinal issues. This study aimed to assess the indications, diagnostic yields, concordance between histopathological and endoscopic findin...

    Authors: Eyad Altamimi, Yousef Odeh, Tuka Al-quraan, Elmi Mohamed and Naif Rawabdeh

    Citation: BMC Pediatrics 2021 21:10

    Content type: Research article

    Published on:

  31. Children with a history of caustic or foreign body ingestion (FBI) seem to be presenting more frequently to emergency departments. This study aims to elucidate the clinical presentation, diagnostic procedures,...

    Authors: Arne Jorma Speidel, Lena Wölfle, Benjamin Mayer and Carsten Posovszky

    Citation: BMC Pediatrics 2020 20:560

    Content type: Research article

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  32. Bazett formula is frequently used in paediatric screening for the long QT syndrome (LQTS) and proposals exist that using standing rather than supine electrocardiograms (ECG) improves the sensitivity of LQTS di...

    Authors: Irena Andršová, Katerina Hnatkova, Kateřina Helánová, Martina Šišáková, Tomáš Novotný, Petr Kala and Marek Malik

    Citation: BMC Pediatrics 2020 20:558

    Content type: Research article

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  33. Nocturnal cough and wheeze are important symptoms when diagnosing any respiratory disease in a child, but objective measurements of these symptoms are not performed.

    Authors: Markus Lindenhofer, Lena Roth, Clemens Mädel, Florian Götzinger, Katharina Kainz, Christiane Lex, Thomas Frischer, Matthias Reinweber and Angela Zacharasiewicz

    Citation: BMC Pediatrics 2020 20:556

    Content type: Research article

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  34. In contrast to intoxications in toddlers which can be due to accidental ingestions, many intoxications in infants are due to medication errors. To our knowledge, this is the first case report of a citalopram into...

    Authors: Jo-Anne Janson, Arthur T. M. Wasylewicz, Marianne Eijkemans and Marieke Kerskes

    Citation: BMC Pediatrics 2020 20:552

    Content type: Case report

    Published on:

  35. The developmental dysplasia of the hip (DDH) can cause a wide range of pathological changes, and often requires surgical treatment. Preoperative evaluation is very important for DDH. We aimed to assess the dia...

    Authors: Huihui Jia, Liang Wang, Yan Chang, Yongrui Song, Yuqi Liu, Fuyong Zhang, Jie Feng, Xiaodong Yang and Mao Sheng

    Citation: BMC Pediatrics 2020 20:550

    Content type: Research article

    Published on:

  36. Medication Errors (MEs) are considered the most common type of error in pediatric critical care services. Moreover, the ME rate in pediatric patients is up to three times higher than the rate for adults. Never...

    Authors: Lorena Michele Brennan-Bourdon, Alan O. Vázquez-Alvarez, Jahaira Gallegos-Llamas, Manuel Koninckx-Cañada, José Luis Marco-Garbayo and Selene G. Huerta-Olvera

    Citation: BMC Pediatrics 2020 20:549

    Content type: Research article

    Published on:

  37. Direct oral anticoagulants, such as apixaban, are increasingly used in everyday practice in order to treat or prevent thromboembolic diseases. To date, there is no available data about apixaban pharmacokinetic...

    Authors: Manon Launay, Yara Nasser, Isabelle Maubert, Anne-Cécile Chaux and Xavier Delavenne

    Citation: BMC Pediatrics 2020 20:546

    Content type: Case report

    Published on:

  38. To evaluate the efficacy of oral clonazepam versus oral lorazepam following initial parenteral benzodiazepine administration to control methamphetamine-induced agitation in children.

    Authors: Fariba Farnaghi, Razieh Rahmani, Hossein Hassanian-Moghaddam, Nasim Zamani, Rebecca McDonald, Narges Gholami and Latif Gachkar

    Citation: BMC Pediatrics 2020 20:543

    Content type: Research article

    Published on:

  39. Galectin-3 is a new biomarker, which plays an important role in tissue inflammation, cardiac remodeling, and fibrosis. It can be readily measured in the circulation to detect early heart failure (HF). This stu...

    Authors: Nagwan Saleh, Ahmed Khattab, Mohamed Rizk, Sherif Salem and Hany Abo-Haded

    Citation: BMC Pediatrics 2020 20:537

    Content type: Research article

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  40. Parafunctional oral habits are known to cause deleterious effects on maxillofacial structures. One such effect is traumatic injuries secondary to chewing inanimate objects like pencils. Following trauma, the l...

    Authors: Anka Sharma, Vikrant O. Kasat, Amit R. Parate, Anirudh Upmanyu and Jaishri S. Pagare

    Citation: BMC Pediatrics 2020 20:530

    Content type: Case report

    Published on:

  41. As part of efforts to develop and implement a short course educational program on pediatric pain management, the current study sought to understand the culture and contextual factors that influence children’s ...

    Authors: Abigail Kusi Amponsah, Evans Oduro, Victoria Bam, Joana Kyei-Dompim, Collins Kwadwo Ahoto and Anna Axelin

    Citation: BMC Pediatrics 2020 20:529

    Content type: Research article

    Published on:

  42. We describe the safety and efficacy of performing pediatric kidney transplantation with a modified extraperitoneal approach that includes mobilization of the native liver and kidney.

    Authors: Mahmoud Alameddine, Joshua S. Jue, Mahmoud Morsi, Javier Gonzalez, Marissa Defreitas, Jayanthi J. Chandar, Jeffrey J. Gaynor and Gaetano Ciancio

    Citation: BMC Pediatrics 2020 20:526

    Content type: Research article

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  43. To study mean core to peripheral temperature difference (CPTD) and the mean lactate levels over the first 6 h of admission to hospital, as indicators of prognosis in critically ill children.

    Authors: Aashish Gupta, Jacob Puliyel, Bhawana Garg and Pramod Upadhyay

    Citation: BMC Pediatrics 2020 20:515

    Content type: Research article

    Published on:

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