Skip to main content

General pediatric medicine and surgery

This section considers studies of general medicine and surgical intervention in children and adolescents.

Page 1 of 12

  1. Defects of bone marrow mesenchymal stem cells (BM-MSCs) in proliferation and differentiation are involved in the pathophysiology of aplastic anemia (AA). Infusion of umbilical cord mesenchymal stem cells (UC-M...

    Authors: Yang Lan, Fang Liu, Lixian Chang, Lipeng Liu, Yingchi Zhang, Meihui Yi, Yuli Cai, Jing Feng, Zhibo Han, Zhongchao Han and Xiaofan Zhu

    Citation: BMC Pediatrics 2021 21:102

    Content type: Research article

    Published on:

  2. Cornell assessment of pediatric delirium (CAPD) showed advantage in diagnosis of pediatric delirium in Chinese critically ill patients. But its performance in surgical patients is still unclear. The present st...

    Authors: Hong Hong, Chao Guo, Zhi-Hua Liu, Bo-Jie Wang, Shu-Zhe Zhou, Dong-Liang Mu and Dong-Xin Wang

    Citation: BMC Pediatrics 2021 21:87

    Content type: Research article

    Published on:

  3. As sleep-related difficulties are a growing public health concern, it is important to gain an overview of the specific difficulty areas of the most vulnerable individuals: children. The current descriptive stu...

    Authors: Christiane Lewien, Jon Genuneit, Christof Meigen, Wieland Kiess and Tanja Poulain

    Citation: BMC Pediatrics 2021 21:82

    Content type: Research article

    Published on:

  4. Cognitive abilities like language, memory, reasoning, visualization, and perceptual functioning shape human action and are considered critical to the successful interaction with the environment. Alternatively,...

    Authors: Fidaa Almomani, Murad O. Al-momani, Soha Garadat, Safa Alqudah, Manal Kassab, Shereen Hamadneh, Grant Rauterkus and Richard Gans

    Citation: BMC Pediatrics 2021 21:71

    Content type: Research article

    Published on:

  5. This study aimed to retrospectively analyze the correlation between congenital abnormality of the urogenital system and various factors in children with neural tube defects (NTDs).

    Authors: Zhi-Hua Hong, Dong-Hui Jin, Xiao-Jian Yuan, Yang Zhao, Hou-Wei Lin and Jie Chen

    Citation: BMC Pediatrics 2021 21:66

    Content type: Research article

    Published on:

  6. For newborns and infants wearing diapers the difficulties in characterizing the appearance of the stool are significant, since the changes in consistency, quantity, and color of the stool are higher than in ot...

    Authors: Laura Cantisano de Deus Silva, Priscila Monaro Bianchini, Erika Veruska Paiva Ortolan, Juliana Fattori Hamamoto, Rosemary Fermiano, Rebeca Mayara Padilha Rego, João César Lyra, Marc Alexander Benninga and Pedro Luiz Toledo de Arruda Lourenção

    Citation: BMC Pediatrics 2021 21:64

    Content type: Research article

    Published on:

  7. The effect of biologic therapy on the incidence of inflammatory bowel disease (IBD)-related hospitalizations is controversial. The high efficacy of biologic agents is weighted against potential therapy-related...

    Authors: Gil Berkovitch, Shlomi Cohen, Ronit Lubetzky, Dana Singer and Anat Yerushalmy-Feler

    Citation: BMC Pediatrics 2021 21:63

    Content type: Research article

    Published on:

  8. Depression in children presents a significant health burden to society and often co-exists with chronic illnesses, such as human immunodeficiency virus (HIV). Research has demonstrated that 10–37% of children ...

    Authors: Agnes Binagwaho, Eric Remera, Alice Uwase Bayingana, Darius Gishoma, Kirstin Woody Scott, Madeline Goosman, Eliza Campbell, Mawuena Agbonyitor, Yvonne Kayiteshonga and Sabin Nsanzimana

    Citation: BMC Pediatrics 2021 21:59

    Content type: Research article

    Published on:

  9. An Anorectal Malformation (ARM) is a rare congenital malformation, which requires proper correction to ensure the best long-term prognosis. These procedures are relatively infrequent and complex, in which a st...

    Authors: J. A. van Ling, G. M. J. Bökkerink, I. de Blaauw and S. M. B. I. Botden

    Citation: BMC Pediatrics 2021 21:57

    Content type: Technical advance

    Published on:

  10. We aimed to study the effectiveness of preoperative thyroid hormone levels in predicting intensive care unit (ICU) mortality after cardiopulmonary bypass (CPB) in infants with congenital heart disease (CHD).

    Authors: Di Yu, Liang Zou, Yueshuang Cun, Yaping Li, Qingfeng Wang, Yaqin Shu and Xuming Mo

    Citation: BMC Pediatrics 2021 21:50

    Content type: Research article

    Published on:

  11. The purpose of this study was to assess scan parameters and to propose strategies to optimize the examinations of children (from 0 to 15 years old) on adult scanners in developing countries.

    Authors: Fotso Eddy Kamdem, Samba Odette Ngano, Clemence Alla Takam, Alain Jervé Fotue, Serge Abogo and Cornellius Lukong Fai

    Citation: BMC Pediatrics 2021 21:44

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Pediatrics 2021 21:93

  12. Paediatric poisoning is a common presentation to emergency departments worldwide. There is a paucity of data on the role of liquid chromatography-tandem mass spectrometry (LC-MS/MS), in the management of paedi...

    Authors: Norbertta Washaya, Alicia Evans, Rudzani Muloiwa, Peter Smith and Heloise Buys

    Citation: BMC Pediatrics 2021 21:42

    Content type: Research article

    Published on:

  13. Imerslund-Gräsbeck syndrome is a rare genetic disease characterised by vitamin B12 deficiency and proteinuria.

    Authors: Visvalingam Arunath, Thabitha Jebaseeli Hoole, Asanka Rathnasri, Oshanie Muthukumarana, Ishara Minuri Kumarasiri, Nishadi Dananjani Liyanage, Yasintha Costa and Sachith Mettananda

    Citation: BMC Pediatrics 2021 21:41

    Content type: Case report

    Published on:

  14. The last two decades brought new treatment options and high quality guidelines into the paediatric rheumatologic practice. Nevertheless, a number of patients still present a diagnostic and therapeutic challeng...

    Authors: Vana Vukić, Ana Smajo, Mandica Vidović, Rudolf Vukojević, Miroslav Harjaček and Lovro Lamot

    Citation: BMC Pediatrics 2021 21:40

    Content type: Case report

    Published on:

  15. Intestinal lymphangiectasia is a rare disease. Thus, prospective studies are impossible, and therapy is still controversial. Several medicines are suggested for treatment but there are no existing indications ...

    Authors: Yiyoung Kwon, Eun Sil Kim, Yon Ho Choe and Mi Jin Kim

    Citation: BMC Pediatrics 2021 21:21

    Content type: Research article

    Published on:

  16. Upper endoscopy is an essential tool for diagnosing pediatric gastrointestinal issues. This study aimed to assess the indications, diagnostic yields, concordance between histopathological and endoscopic findin...

    Authors: Eyad Altamimi, Yousef Odeh, Tuka Al-quraan, Elmi Mohamed and Naif Rawabdeh

    Citation: BMC Pediatrics 2021 21:10

    Content type: Research article

    Published on:

  17. Children with a history of caustic or foreign body ingestion (FBI) seem to be presenting more frequently to emergency departments. This study aims to elucidate the clinical presentation, diagnostic procedures,...

    Authors: Arne Jorma Speidel, Lena Wölfle, Benjamin Mayer and Carsten Posovszky

    Citation: BMC Pediatrics 2020 20:560

    Content type: Research article

    Published on:

  18. Bazett formula is frequently used in paediatric screening for the long QT syndrome (LQTS) and proposals exist that using standing rather than supine electrocardiograms (ECG) improves the sensitivity of LQTS di...

    Authors: Irena Andršová, Katerina Hnatkova, Kateřina Helánová, Martina Šišáková, Tomáš Novotný, Petr Kala and Marek Malik

    Citation: BMC Pediatrics 2020 20:558

    Content type: Research article

    Published on:

  19. Nocturnal cough and wheeze are important symptoms when diagnosing any respiratory disease in a child, but objective measurements of these symptoms are not performed.

    Authors: Markus Lindenhofer, Lena Roth, Clemens Mädel, Florian Götzinger, Katharina Kainz, Christiane Lex, Thomas Frischer, Matthias Reinweber and Angela Zacharasiewicz

    Citation: BMC Pediatrics 2020 20:556

    Content type: Research article

    Published on:

  20. In contrast to intoxications in toddlers which can be due to accidental ingestions, many intoxications in infants are due to medication errors. To our knowledge, this is the first case report of a citalopram into...

    Authors: Jo-Anne Janson, Arthur T. M. Wasylewicz, Marianne Eijkemans and Marieke Kerskes

    Citation: BMC Pediatrics 2020 20:552

    Content type: Case report

    Published on:

  21. The developmental dysplasia of the hip (DDH) can cause a wide range of pathological changes, and often requires surgical treatment. Preoperative evaluation is very important for DDH. We aimed to assess the dia...

    Authors: Huihui Jia, Liang Wang, Yan Chang, Yongrui Song, Yuqi Liu, Fuyong Zhang, Jie Feng, Xiaodong Yang and Mao Sheng

    Citation: BMC Pediatrics 2020 20:550

    Content type: Research article

    Published on:

  22. Medication Errors (MEs) are considered the most common type of error in pediatric critical care services. Moreover, the ME rate in pediatric patients is up to three times higher than the rate for adults. Never...

    Authors: Lorena Michele Brennan-Bourdon, Alan O. Vázquez-Alvarez, Jahaira Gallegos-Llamas, Manuel Koninckx-Cañada, José Luis Marco-Garbayo and Selene G. Huerta-Olvera

    Citation: BMC Pediatrics 2020 20:549

    Content type: Research article

    Published on:

  23. Direct oral anticoagulants, such as apixaban, are increasingly used in everyday practice in order to treat or prevent thromboembolic diseases. To date, there is no available data about apixaban pharmacokinetic...

    Authors: Manon Launay, Yara Nasser, Isabelle Maubert, Anne-Cécile Chaux and Xavier Delavenne

    Citation: BMC Pediatrics 2020 20:546

    Content type: Case report

    Published on:

  24. To evaluate the efficacy of oral clonazepam versus oral lorazepam following initial parenteral benzodiazepine administration to control methamphetamine-induced agitation in children.

    Authors: Fariba Farnaghi, Razieh Rahmani, Hossein Hassanian-Moghaddam, Nasim Zamani, Rebecca McDonald, Narges Gholami and Latif Gachkar

    Citation: BMC Pediatrics 2020 20:543

    Content type: Research article

    Published on:

  25. Galectin-3 is a new biomarker, which plays an important role in tissue inflammation, cardiac remodeling, and fibrosis. It can be readily measured in the circulation to detect early heart failure (HF). This stu...

    Authors: Nagwan Saleh, Ahmed Khattab, Mohamed Rizk, Sherif Salem and Hany Abo-Haded

    Citation: BMC Pediatrics 2020 20:537

    Content type: Research article

    Published on:

  26. Parafunctional oral habits are known to cause deleterious effects on maxillofacial structures. One such effect is traumatic injuries secondary to chewing inanimate objects like pencils. Following trauma, the l...

    Authors: Anka Sharma, Vikrant O. Kasat, Amit R. Parate, Anirudh Upmanyu and Jaishri S. Pagare

    Citation: BMC Pediatrics 2020 20:530

    Content type: Case report

    Published on:

  27. As part of efforts to develop and implement a short course educational program on pediatric pain management, the current study sought to understand the culture and contextual factors that influence children’s ...

    Authors: Abigail Kusi Amponsah, Evans Oduro, Victoria Bam, Joana Kyei-Dompim, Collins Kwadwo Ahoto and Anna Axelin

    Citation: BMC Pediatrics 2020 20:529

    Content type: Research article

    Published on:

  28. We describe the safety and efficacy of performing pediatric kidney transplantation with a modified extraperitoneal approach that includes mobilization of the native liver and kidney.

    Authors: Mahmoud Alameddine, Joshua S. Jue, Mahmoud Morsi, Javier Gonzalez, Marissa Defreitas, Jayanthi J. Chandar, Jeffrey J. Gaynor and Gaetano Ciancio

    Citation: BMC Pediatrics 2020 20:526

    Content type: Research article

    Published on:

  29. Benign convulsions with mild gastroenteritis (BCWG) is a common condition in children in Asia and is generally not associated with pH or electrolyte imbalances. When BCWG is diagnosed, a lumbar puncture is usu...

    Authors: Xiao-sheng Hao, Jian-min Liang, Xue-mei Wu, Yun-peng Hao, Jiang-tao Wang and Song-yan Liu

    Citation: BMC Pediatrics 2020 20:516

    Content type: Research article

    Published on:

  30. To study mean core to peripheral temperature difference (CPTD) and the mean lactate levels over the first 6 h of admission to hospital, as indicators of prognosis in critically ill children.

    Authors: Aashish Gupta, Jacob Puliyel, Bhawana Garg and Pramod Upadhyay

    Citation: BMC Pediatrics 2020 20:515

    Content type: Research article

    Published on:

  31. The long-term prognosis of Henoch-Schönlein purpura (HSP) depends on the severity of renal involvement, and crescent formation is considered an important risk factor for poor prognosis of Henoch-Schönlein purp...

    Authors: Yong-Rui Song, Wan-Liang Guo, Mao Sheng, Qiang Lin, Xue-Ming Zhu and Xiao-Zhong Li

    Citation: BMC Pediatrics 2020 20:501

    Content type: Research article

    Published on:

  32. There is no globally accepted definition for dosing error in adult or pediatric practice. The definition of pediatric dosing error varies greatly in the literature. The objective of this study was to develop a fr...

    Authors: Nadia Roumeliotis, Eleanor Pullenayegum, Paula Rochon, Anna Taddio and Chris Parshuram

    Citation: BMC Pediatrics 2020 20:488

    Content type: Research article

    Published on:

  33. Rosai- Dorfman Disease (RDD) is a benign condition of unknown aetiology which is characterized by non-neoplastic proliferation of histiocytes. Pathophysiology and natural history remain obscure due to the low ...

    Authors: Tharmini Danisious, Mathula Hettiarachchi, Chanuka Dharmadasa and Heshan Jayaweera

    Citation: BMC Pediatrics 2020 20:470

    Content type: Case report

    Published on:

  34. The hospital patient pathway for having treatment procedures can be daunting for younger patients and their family members, especially when they are about to undergo a complex intervention. Opportunities to me...

    Authors: Lisa Aufegger, Khánh Hà Bùi, Colin Bicknell and Ara Darzi

    Citation: BMC Pediatrics 2020 20:469

    Content type: Research article

    Published on:

  35. With increased use of telehealth, interventions to improve infant sleep environments have not been explored. This study sought to assess the feasibility and efficacy of using electronic health record patient p...

    Authors: Ethan A. Canty, Benjamin N. Fogel, Erich K. Batra, Eric W. Schaefer, Jessica S. Beiler and Ian M. Paul

    Citation: BMC Pediatrics 2020 20:468

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Pediatrics 2020 20:493

  36. Hirschsprung-associated enterocolitis (HAEC) is the most severe and potentially lethal complication of Hirschsprung disease (HSCR) which might occur following definitive surgery. Our objectives were: 1) to com...

    Authors: Gunadi, Afnandito Valeno Risky Sukarelawanto, Azmi Ritana, Naisya Balela, Wayan Julita Krisnanti Putri, Dian Nirmala Sirait, Vincentia Meta Widya Paramita, Andika Purba Sasmita, Andi Dwihantoro and Akhmad Makhmudi

    Citation: BMC Pediatrics 2020 20:457

    Content type: Research article

    Published on:

  37. The Global Trigger Tool (GTT),which is a method using “triggers” to review medical record retrospectively to identify possible adverse events. Several studies showed that the GTT was effective. However, there ...

    Authors: Yi Liu, Junfeng Yan, Yunfei Xie and Yuan Bian

    Citation: BMC Pediatrics 2020 20:454

    Content type: Research article

    Published on:

  38. Young children and those with chronic medical conditions are at risk for complications of influenza including cardiopulmonary compromise. Here we aim to examine risks of mortality, clinical complications in ch...

    Authors: Laxmi V. Ghimire, Fu-Sheng Chou and Anita J. Moon-Grady

    Citation: BMC Pediatrics 2020 20:450

    Content type: Research article

    Published on:

  39. Type 1 diabetes (T1D) is caused by immune-mediated destruction of the β-cells. After initiation of insulin therapy many patients experience a period of improved residual β-cell function leading to partial dise...

    Authors: Anne Julie Overgaard, Jens Otto Broby Madsen, Flemming Pociot, Jesper Johannesen and Joachim Størling

    Citation: BMC Pediatrics 2020 20:446

    Content type: Research article

    Published on:

  40. Extravasation injury resulting from intravenous therapies delivered via peripheral intravenous catheters or umbilical and peripherally inserted central venous catheters is a common iatrogenic complication occu...

    Authors: Kam Ming Chan, Janita Pak Chun Chau, Kai Chow Choi, Genevieve Po Gee Fung, Wai Wa Lui, Meme Suk Ying Chan and Suzanne Hoi Shan Lo

    Citation: BMC Pediatrics 2020 20:445

    Content type: Research article

    Published on:

  41. In populations above 3,000 meters above sea level (m.a.s.l.) normal values of oxygen saturation (SpO2) above 90% have been reported. Few studies have been conducted in cities of moderate altitude (between 2,50...

    Authors: Vinicio Andrade, Felipe Andrade, Pablo Riofrio, Fúlvio B. Nedel, Miguel Martin and Natalia Romero-Sandoval

    Citation: BMC Pediatrics 2020 20:440

    Content type: Research article

    Published on:

  42. Managing children with minor head trauma remains challenging for physicians who evaluate for the need for computed tomography (CT) imaging for clinically important traumatic brain injury (ciTBI) identification...

    Authors: Rasha D. Sawaya, Cynthia Wakil, Adonis Wazir, Sami Shayya, Iskandar Berbari, Rawan Safa, Maha Makki, Mahdi Hamade and Hani Tamim

    Citation: BMC Pediatrics 2020 20:439

    Content type: Research article

    Published on:

  43. Drooling is common in children with neurological disorders, but its management is very challenging, Scopolamine transdermal patch (STP) appears to be useful in controlling drooling, although it is not approved...

    Authors: Majed Al Jeraisy, Maissa AlFuraih, Raghad AlSaif, Bushra AlKhalifah, Hazza AlOtaibi and Mostafa A. Abolfotouh

    Citation: BMC Pediatrics 2020 20:437

    Content type: Research article

    Published on: