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Table 1 Population characteristics evaluated according to AAD incidence

From: Antibiotic associated diarrhea in outpatient pediatric antibiotic therapy

 

Cases w/o AAD

N = 679

Cases w AAD

N = 79

p

Age (years; IQR)

4.9 (2.6–8.0)

3.5 (1.7–8.9)

 

Gendera

  

0.10

 Male

360 (53)

36 (45)

 

Age groupsa

  

0.10

 1–24 months

122 (85.3)

21 (14.7)

 

 2–7 years

323 (91.2)

31 (8.8)

 

 7–12 years

170 (91.4)

13 (6.9)

 

  > 12 years

74 (85.1)

13 (14.9)

 

Geographic regionsa

  

0.014*

 Eastern Anatolia

15 (75)

5 (25)

 

 Southeast Anatolia

136 (83.5)

27 (16.5)

 

 Mediterranean Region

30 (85.8)

5 (14.2)

 

 Central Anatolia

184 (90.4)

20 (9.6)

 

 Marmara Region

215 (93.2)

15 (6.8)

 

 Aegean Region

55 (93)

4 (7)

 

 Black Sea Region

42 (93.4)

3 (6.6)

 

Type of infectiona

  

0.16

 Acute tonsillopharyngitis

174 (87.4)

24 (12.1)

 

 Lower respiratory infection

112 (93.3)

8 (6.7)

 

 Acute otitis media

103 (85)

17 (15)

 

 Acute rhinosinusitis

105 (92.1)

9 (7.9)

 

 Soft tissue infection

45 (84.9)

8 (15.1)

 

 Urinary tract infection

45 (86.5)

7 (13.5)

 

 Acute lymphadenitis

78 (92.9)

6 (7.1)

 

 Others

17 (100)

-

 

Treatments and dosesa

  

0.48

 Aminopenicillins

  Amoxicillin/clavulanic acid (usual dose)b

250 (91.6)

23 (8.4)

 

  Amoxicillin/clavulanic acid (high dose)c

142 (87.7)

20 (12.3)

 

  Amoxicillin/clavulanic acid (max dose)d

30 (83.3)

6 (16.7)

 

  Amoxicillin (high dose)c

3 (100)

-

 

  Amoxicillin (usual dose)b

8 (100)

-

 

  Ampicillin/sulbactamb

4 (100)

-

 

 Cephalosporins

107 (85.6)

18 (14.4)

 

  Cefuroximee

28 (92.9)

2 (7.1)

 

  Cefdinirf

43 (79.6)

11 (20.4)

 

  Cefiximeg

36 (87.8)

5 (12.2)

 

 Macrolidesh

64 (94)

4 (6)

 

 Phenoxymethyl penicillini

51 (89.5)

6 (10.5)

 

 Others

19 (92.4)

2 (7.6)

 
  1. aExpressed as percentages; b40-60 mg/kg/day; c80-90 mg/kg/day; d2gr/d; e10-40 mg/kg/d; f14mg/kg/d; g8 mg/kg/d; hclarithromycin: 15–30 mg/kg/d, azithromycin: 10–15 mg/kg/d; i30-80 mg/kg/d
  2. *Overall comparison of the regions