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Table 3 Spearman rank correlation coefficients between FGF19 protein,VEGF protein,sklotho protein and selected risk factors in children with type 1 diabetes

From: Relationship between serum fibroblast growth factor 19 and vascular endothelial growth factor and soluble klotho protein in type 1 diabetic children

Variable

 

FGF19

 

VEGF

 

sklotho

 

r (P value)

 

r (P value)

 

r (P value)

Age [years]

 

r=−0.227,P = 0.067

 

r = 0.215,P = 0.083

 

r=−0.160,P = 0.199

Gender [male %]

 

r = 0.123,P = 0.327

 

r = 0.040,P = 0.750

 

r = 0.177,P = 0.154

T1D duration [years]

 

r=−0.029,P = 0.818

 

r = 0.095,P = 0.449

 

r = 0.112,P = 0.370

BMI [kg/m2]

 

r=−0.063,P = 0.613

 

r = 0.046,P = 0.711

 

r=−0.096,P = 0.445

HbA1c [%]

 

r=−0.349,P = 0.004

 

r = 0.302,P = 0.014

 

r=−0.342,P = 0.005

Glucose [mmol/L]

 

r=−0.128,P = 0.307

 

r=−0.020,P = 0.875

 

r=−0.135,P = 0.280

Totalcholesterol [mmol/L]

 

r = 0.032,P = 0.797

 

r=−0.014,P = 0.913

 

r = 0.176,P = 0.158

HDL cholesterol [mmol/L]

 

r = 0.067,P = 0.594

 

r = 0.091,P = 0.467

 

r = 0.027,P = 0.833

LDL cholesterol [mmol/L]

 

r = 0.142,P = 0.256

 

r=−0.043,P = 0.733

 

r = 0.135,P = 0.281

Triglycerides [mmol/L]

 

r=−0.049,P = 0.698

 

r = 0.046,P = 0.715

 

r=−0.004,P = 0.975

TDD [IU/kg]

 

r=−0.205,P = 0.099

 

r = 0.055,P = 0.662

 

r=−0.026,P = 0.835

Basal insulin dose [%of TDD]

 

r = 0.070,P = 0.579

 

r = 0.339,P = 0.006

 

r=−0.105,P = 0.405

FGF−19 [pg/mL]

 

-

 

r=−0.335,P = 0.006

 

r = 0.247,P = 0.045

VEGF [pg/mL]

 

r=−0.335,P = 0.006

 

-

 

r = 0.000,P = 0.999

sklotho [pg/mL]

 

r = 0.247,P = 0.0.045

 

r = 0.000,P = 0.999

 

-