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Fig. 1 | BMC Pediatrics

Fig. 1

From: Molecular characterization of the circadian clock in paediatric leukaemia patients: a prospective study protocol

Fig. 1

Study protocol flow chart. After meeting the study inclusion criteria, patients and control participants are included in their respective groups. Saliva, blood and bone marrow sampling is carried out according to the scheme in Fig. 2. From the blood and bone marrow samples PBMC are isolated and further undergo separation into CD19± cells for ALL and CD33± for AML. Afterwards RNA is extracted, qPCR analysis is carried out to quantify the expression of core-clock genes. This procedure is repeated for each patient

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