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Table 1 Univariable analysis for risk factors of coronary artery aneurysm persistence

From: Development of a nomogram prediction model for early identification of persistent coronary artery aneurysms in kawasaki disease

Variables

CAA regression (n = 76)

CAA persistence (n = 29)

Sig.

Gender

  

0.633

 Female

23 (30.27%)

7 (24.14%)

 

 Male

53 (69.73%)

22 (75.86%)

 

 Complications in CNS

21 (27.63%)

7 (24.14%)

0.808

 Incomplete KD

40 (52.63%)

16 (55.17%)

0.831

 IVIG resistance

19 (25.00%)

9 (31.03%)

0.623

 Relapsed KD

29 (38.16%)

8 (27.58%)

0.366

 White blood cell (×109/L)

14.25 ± 5.07

14.07 ± 5.98

0.882

 Neutrophils (%)

64.31 ± 13.96

74.42 ± 11.01

0.001*

 Lymphocyte (%)

25.37 ± 11.92

18.32 ± 8.71

0.004*

 Ratio of neutrophils to lymphocyte

3.65 ± 3.76

5.73 ± 4.19

0.016*

 Monocyte (%)

10.31 ± 4.08

7.25 ± 3.97

0.001*

 Hemoglobin (g/L)

107.61 ± 12.06

111.17 ± 10.85

0.167

 Platelet (×109/L)

352.14 ± 150.97

394.34 ± 166.93

0.216

 Ratio of platelet to lymphocyte

125.33 ± 82.08

186.91 ± 129.49

0.005*

 CRP (mg/L)

87.35 ± 55.21

78.68 ± 48.41

0.459

 ESR (mm/h)

59.97 ± 28.62

70.84 ± 32.34

0.115

 Alanine aminotransferase (ALT, U/I)

57.92 ± 65.26

71.31 ± 117.60

0.461

 Aspartate aminotransferase (AST, U/I)

50.29 ± 59.88

104.03 ± 130.87

0.005*

 Ratio of AST to ALT

1.28 ± 0.77

2.41 ± 1.82

0.000*

 Total Bilirubin (umol/L)

9.37 ± 10.06

8.53 ± 14.14

0.741

 Direct bilirubin (DBIL, umol/L)

5.94 ± 8.24

4.74 ± 12.30

0.598

 Indirect bilirubin (umol/L)

4.21 ± 3.47

3.87 ± 3.64

0.682

 Albumin (ALB, g/L)

35.72 ± 6.52

36.99 ± 5.94

0.366

 Prealbumin (PA, g/L)

62.83 ± 31.37

72.69 ± 46.85

0.422

 γ-Glutamyl transpeptidase (γ-GT, U/L)

88.26 ± 92.75

41.76 ± 31.24

0.009*

 Lactate dehydrogenase (LDH, U/L)

383.79 ± 193.87

394.17 ± 202.01

0.812

 Urea nitrogen (UN, mmol/L)

3.26 ± 1.86

3.45 ± 3.11

0.723

 Creatinine (Cr, umol/L)

28.48 ± 11.55

31.17 ± 14.99

0.344

 Serum cystain C (CysC, umol/L)

1.01 ± 0.38

0.94 ± 0.52

0.667

  K+ (mmol/L)

4.26 ± 0.58

4.18 ± 0.68

0.568

 Na+ (mmol/L)

134.86 ± 15.03

137.31 ± 4.73

0.393

 P- (mmol/L)

1.33 ± 0.28

1.41 ± 0.27

0.201

 Cl- (mmol/L)

102.39 ± 3.83

102.22 ± 3.84

0.844

 Ca2+ (mmol/L)

2.28 ± 0.15

2.28 ± 0.18

0.826

 Mg2+ (mmol/L)

0.93 ± 0.14

0.92 ± 0.09

0.709

 Total cholesterol (TC, mmol/L)

3.04 ± 0.82

3.40 ± 0.69

0.184

 Triglyceride (TG, mmol/L)

1.38 ± 0.50

1.72 ± 1.46

0.277

 HDL-C (mmol/L)

0.51 ± 0.18

0.63 ± 0.29

0.072

 LDL-C (mmol/L)

2.23 ± 0.81

2.24 ± 0.87

0.982

 PT (s)

14.06 ± 2.71

13.15 ± 1.18

0.140

 APTT (s)

36.60 ± 8.87

35.57 ± 6.68

0.638

 Fibrinogen (Fg, mg/dL)

531.19 ± 147.43

556.95 ± 133.44

0.497

 D-dimer (mg/L)

2.01 ± 1.44

1.86 ± 1.76

0.789

 CTnI (ug/L)

0.02 ± 0.04

0.02 ± 0.02

0.740

 NT-BNP (pg/ml)

2384.06 ± 4601.73

2279.28 ± 5989.78

0.941

 Cardiac enlargement

13 (17.11%)

3 (10.34%)

0.547

 Valver regurgitation

16 (21.05%)

4 (13.79%)

0.289

 Number of lesions

  

0.000*

 1

67 (88.16%)

15 (51.72%)

 

 2

6 (7.89%)

8 (27.60%)

 

 3

3 (3.95%)

3 (10.34%)

 

 4

0 (0%)

3 (10.34%)

 

 Aneurysm classification

  

0.000*

 Small

73 (96.05%)

12 (41.38%)

 

 Medium

3 (3.95%)

13 (44.83%)

 

 Large

0 (0%)

4 (13.79%)

 

 Location of aneurysm

  

0.000*

 Left coronary artery (LCA)

57 (75.00%)

11 (37.93%)

 

 Left anterior descending artery (LAD)

5 (6.58%)

5 (17.24%)

 

 Left circumflex artery (LCX)

0 (0.00%)

0 (0.00%)

 

 Right coronary artery (RCA)

14 (18.42%)

13 (44.83%)

 

 Aneurysm size

3.37 ± 0.34

5.10 ± 2.52

0.000*