Table 4 Factors associated with mortality amongst neonates with moderate to severe encephalopathy who were not cooled

Birth weight categories

 ≥ 2500 g

76/103 (73.8)

72/90 (80.0)

1

N/A

N/A

 < 2500 g

27/103 (26.2)

18/90 (20.0)

1.42 (0.72–2.81)

0.31

Gestational age categories

 ≥ 38 weeks

65/100 (65.0)

27/89 (69.7)

1

_

N/A

N/A

 < 38 weeks

35/100 (35.0)

62/89 (30.3)

1.24 (0.67–2.28)

0.497

Sex

 Female

35/103 (34.0)

40/90 (44.4)

1

_

N/A

N/A

 Male

68/103 (66.0)

50/90 (55.6)

1.55 (0.86–2.80)

0.138

Apgar score at 5 min

 ≥ 4

22/97 (22.7)

66/86 (76.7)

1

_

1

 0–3

75/97 (77.3)

20/86 (23.3)

11.2 (4.94–25.6)

< 0.001

0.94 (0.66–1.35)

0.752

Time to First Breath

 < 20 min

19/62 (30.6)

47/63 (74.6)

1

_

1

 ≥ 20 min

43/62 (69.4)

16/63 (25.4)

6.65 (2.77–16.0)

< 0.001

0.48 (0.08–2.76)

0.413

Sarnat staging

 Stage 2 (moderate encephalopathy)

13/103 (12.6)

71/90 (78.9)

1

1

 Stage 3 (severe encephalopathy)

90/103 (97.4)

19/90 (21.1)

25.9 (9.17–73.0)

< 0.001

51.5 (5.86–453)

< 0.001

Thompson score

 ≤ 10

3/65 (4.6)

40/83 (48.2)

1

1

 > 10

62/65 (95.4)

43/83 (51.8)

19.2 (4.69–78.8)

< 0.001

1.21 (0.12–11.9)

0.871

Arterial blood gas, pH

 ≥ 7.00

11/92 (12.0)

36/71 (58.7)

1

1

 < 7.00

81/92 (88.0)

35/71 (49.3)

7.57 (3.18–18.0)

< 0.001

3.40 (0.45–25.5)

0.234

Arterial blood gas, base deficit (mmols/L)

 ≤ 16

12/92 (13.0)

36/85 (42.4)

1

1

 > 16

80/92 (87.0)

49/85 (57.6)

4.90 (2.22–10.8)

< 0.001

0.59 (0.09–3.91)

0.586