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Table 2 Univariate analysis of DKA

From: Clinical characteristics of 683 children and adolescents, aged 0–18 years, newly diagnosed with type 1 diabetes mellitus in Henan Province: a single-center study

 

DKA (n = 430)

Non DKA (n = 253)

P value

Age (years)

  

0.009*

 0–3 years

167 (38.8%)

69 (27.3%)

 

 4–9 years

134 (31.1%)

95 (37.5%)

 

 10–18 years

129 (30%)

89 (35.2%)

 

Sex (male)

220 (51.2%)

137 (31.9%)

0.45

Father occupation

  

0.664

 Industrial and agricultural workers

201 (46.7%)

105 (41.5%)

 

  Service workers

22 (5.1%)

14 (5.5%)

 

  Civil servants and employees of enterprises and institutions

43 (10%)

22 (8.7%)

 

  Professional and technical staff

10 (2.3%)

8 (3.2%)

 

  Self-employment

72 (16.7%)

45 (17.8%)

 

  Other

82 (19.1%)

59 (23.3%)

 

Mother occupation

  

0.717

 Industrial and agricultural workers.

181 (42.1%)

96 (37.9%)

 

  Service workers

15 (3.5%)

13 (5.1%)

 

  Civil servants and employees of enterprises and institutions

45 (10.5%)

22 (8.7%)

 

  Professional and technical staff

6 (1.4%)

4 (1.6%)

 

  Self-employment

61 (14.2%)

40 (15.8%)

 

  Other

122 (28.4%)

78 (30.8%)

 

Onset season

  

0.167

  Spring

94 (21.9%)

60 (23.7%)

 

  Summer

98 (22.8%)

71 (27.4%)

 

  Autumn

118 (27.4%)

52 (20.5%)

 

  Winter

120 (27.9%)

70 (27.7%)

 

Family history positivity

76 (17.7%)

54 (21.3%)

0.238

HbA1c at onset (%)

12.11 ± 2.66

11.59 ± 2.80

0.017*

C-peptide at onset (nmol/L)

0.28 (0.16,0.43)

0.42 (0.28,0.67)

< 0.001*

Blood glucose at onset (mmol/L)

23.43 ± 6.91

20.34 ± 7.21

< 0.001*

25OHD (ng/mL)

17.99 ± 7.72

19.57 ± 8.50

0.013*

ICA positivity

18 (4.1%)

10 (3.9%)

0.882

IAA positivity

105 (24.4%)

59 (23.3%)

0.746

GADA positivity

220 (51.2%)

126 (49.8%)

0.731

  1. *means P value< 0.05, statistically significant between the two groups
  2. 25OHD 25-hydroxyvitamin D, HbA1c Hemoglobin A1C, DKA Diabetic ketoacidosis, ICA Islet cell autoantibody, IAA Insulin autoantibody, GADA Glutamic acid decarboxylase antibody