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Table 2 Proportion of neonates with Peak drug concentrations falling within the recommended ranges

From: Plasma concentration and eGFR in preterm and term neonates receiving gentamicin or successive amikacin therapy

 

Peak concentration (Cmax)

Proportion of patients

Gentamicin (n = 44)

Below target range: < 15 mcg/mL

40.9%

Within target range: 15–25 mcg/mL

27.3%

Above target range: > 25 mcg/mL

31.8%

Amikacin (n = 35)

Below target range: < 30 mcg/mL

8.6%

Within target range: 30–40 mcg/mL

2.9%

Above target range: > 40 mcg/mL

88.6%

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BMC Pediatrics

ISSN: 1471-2431

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