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Table 1 Characteristics of eligible children categorized by anesthesia method

From: Comparison of bleeding complications after pediatric kidney biopsy between intravenous sedation and general anesthesia: a nationwide cohort study

Variable

Category

Using general anesthesia

Using intravenous sedation only

P-value

n=1164

n=5396

Age

1–5 years

358 (30.8%)

876 (16.2%)

<0.001

6–11 years

619 (53.2%)

2568 (47.6%)

 

12–15 years

187 (16.1%)

1952 (36.2%)

 

Male

 

682 (58.6%)

3035 (56.2%)

0.14

Body mass index

Underweight

93 (8.0%)

536 (9.9%)

0.007

Normal

859 (73.8%)

4046 (75.0%)

 

Overweight

212 (18.2%)

814 (15.1%)

 

Kidney disease

Nephritis

725 (62.3%)

3519 (65.2%)

0.058

Nephrotic syndrome

439 (37.7%)

1877 (34.8%)

 

Comorbid kidney failure

9 (0.8%)

36 (0.7%)

0.69

Acute kidney injury/acute or rapidly progressive disease

16 (1.4%)

81 (1.5%)

0.75

Use of antiplatelets or anticoagulants

11 (0.9%)

104 (1.9%)

0.021

Comorbid anemia on admission

18 (1.5%)

38 (0.7%)

0.005

Coagulation disorders on admission

11 (0.9%)

37 (0.7%)

0.35

Metabolic disease

70 (6.0%)

311 (5.8%)

0.74

Mental disease

18 (1.5%)

58 (1.1%)

0.17

Neurological disease

15 (1.3%)

38 (0.7%)

0.043

Cardiovascular disease

215 (18.5%)

797 (14.8%)

0.002

Respiratory disease

137 (11.8%)

470 (8.7%)

0.001

Musculoskeletal disease

67 (5.8%)

376 (7.0%)

0.14

Congenital disease

12 (1.0%)

40 (0.7%)

0.31

Use of corticosteroids

137 (11.8%)

565 (10.5%)

0.19

Use of immunosuppressants

142 (12.2%)

679 (12.6%)

0.72

Use of tranexamic acid

529 (45.4%)

2189 (40.6%)

0.002

Use of albumin infusion

9 (0.8%)

47 (0.9%)

0.74

Hospital volume (cases/year)

1–5

491 (42.2%)

1628 (30.2%)

<0.001

6–12

396 (34.0%)

1804 (33.4%)

 

13–

277 (23.8%)

1964 (36.4%)

 

Academic hospital admission

486 (41.8%)

2394 (44.4%)

0.10

History of biopsy at the same hospital

136 (11.7%)

743 (13.8%)

0.058

Fiscal year

2010

59 (5.1%)

397 (7.4%)

<0.001

2011

73 (6.3%)

468 (8.7%)

 

2012

129 (11.1%)

631 (11.7%)

 

2013

141 (12.1%)

694 (12.9%)

 

2014

173 (14.9%)

790 (14.6%)

 

2015

171 (14.7%)

821 (15.2%)

 

2016

190 (16.3%)

797 (14.8%)

 

2017

228 (19.6%)

798 (14.8%)

 

Length of stay (days)

11.0 (14.3)

9.0 (11.2)

<0.001

Total hospitalization costs (US dollars)

4986 (5531)

3381 (4648)

<0.001

Complication following biopsy

27 (2.3%)

151 (2.8%)

0.43

  1. Data are presented as mean (standard deviation) for continuous measures and as n (%) for categorical measures