Table 1 Unmet needs and data gaps in pediatric cough according to international experts
What, in your opinion, are the greatest unmet needs in pediatric cough? (n = 14) | |
Treatment | Etiology and progression |
Effective, safe treatment for acute viral cough | Understanding causes |
Faster improvement/resolution of cough symptoms | Understanding different cough phenotypes and their treatment |
Cough medication for children aged < 2 years | Other Education in a preschool setting on the prevention and management of respiratory infection Allergy [unspecified] Clinical studies in pediatric populations [unspecified] |
Effective, safe treatment for acute cough that interferes with sleep | |
Mucolytics for dry cough | |
Specific cough suppressants | |
Testing and treatment for suspected recurrent viral bronchitis | Â |
What data gaps are there in pediatric cough research that you would like to see addressed in a clinical study? (n = 12) | |
Treatment | Etiology and progression |
Controlled clinical trial on suggestion therapy for habit cough | Determining cough phenotypes in different age groups |
Effective treatment of viral cough | Is wet/dry cough accurately reported, and does it change over time? |
Effectiveness of over-the-counter drugs | Main sources of respiratory infection in preschool children |
Efficacy and safety of symptomatic cough drugs (e.g., secretolytics, mucolytics, antitussives, and protussives) | Prevalence of chronic cough with accurate assessment of causes |
Safety and effective dosing of drugs in children aged < 2 years | Prevalence of pertussis causing prolonged cough |
Study of herbal versus allopathic chemicals | Cough receptor sensitivity in children |
Testing and treatment for suspected recurrent viral bronchitis | Other Advanced allergic tests Rapid diagnosis of pertussis in patients with prolonged cough National guidelines [unspecified] |