Author/ year | Number of participants | Study method | primary outcome(findings) |
---|---|---|---|
Shevchenko N., Khadzhynova Y. 2019 [25] | Total:69 | Case–control | No correlation between vitamin D status and activity of disease (r-0.11; P > 0. 05) No correlation between vitamin D status and number of active joints( r-0.05; P > 0.05) No correlation between vitamin D status and number of injured joints (r-0. 14; P > 0.05) |
Haugen et al. 1992 [26] | Total:32 JCA:15 Control:17 | Case–control | Significantly lower weight in PA group than the healthy controls (p = 0.01) and pauci-A (p = 0.02) Iron and zinc in the PA group compared to Pauci-A (p = 0.02) and healthy controls (both p < 0.01) Significantly higher disease activity and ESR in the PA group with the pauci-A (p = 0.02 and p < 0.01 respectively) Positive correlation seen between ESR and the disease activity t (r = 0.54, p < 0.01) |
Lofthose et al. 2002 [27] | Total:44 JIA:22 Control:22 | Case–control | Significantly lower body fat percentage seen in Pauci-A than in controls (P = 0.027) |
Honkanen et al. 1990 [28] | Total:137 Control:12 JCA:125 | Case–control | chol correlated with the markers of disease activity by ESR and Hb (r = -.193,p = 0.002 and r = 0.208,p = 0.02) Possessive correlation between serum zinc and chol(r = 0.227,p = 0.002) Significant correlation between Zinc and Vit A in serum( p < 0.001) |
Harper et al. 2000 [29] | Total:78 JRA:44 Control:34 | Case–control | JRA Children with TMD reported significantly greater jaw pain, impaired ability to chew, and impaired quality of life before chewing(P < 0.05, P < 0.001)and after(P < 0.05) than did either JRA or control children |
Gorczyca et al. 2017 [30] | Total:108 JIA:66 Control:42 | Case–control | Negative correlation between n-3 and n-6 PUFAs with CRP and ESR (p < 0.05) Positive correlation between n-3 and n-6 PUFAs and platelet count (p < 0.05) |
Bacon et al. 1990 [31] | Total:43 JIA:34 Control: 9 | Case–control | A significant abnormality was seen in nutritional status in systemic and PA JRA •Zin( p ≤ 05) •Vit A, C and copper: (p ≤ .O1) No significant correlation between diet, nutritional status and growth in any of the three types of JRA |
Bouaddi et al. 2014 [10] | Total:40 | Cross-sectional | Serum 25(OH) D were associated with DAS28 (p = 0.04, β: − 3.87, CI: (− 7.67,-0.07) serum 25(OH)D levels were associated with the following disease activity components: ESR (p = 0.05, β: − 0.14, CI: (− 0.28,0.004)), Tender joints (p = 0.02, β: − 0.79, CI (− 1.47,-0.10)) Patient global health (p = 0.04, β: − 0.17, CI: (− 0.35,-0.004) |
Grönlund et al. 2014 [32] | Total:80 JIA:40 Control:40 | Cross-sectional cohort | Positive correlation between CHAQ and number of active joints with the proportion of body fat (R 0.48, p 0.002 and R 0.34, p 0.034, respectively) |
Gonçalves et al. 2007 [33] | Total:103 JIA:51 Control: 52 | Cross-sectional with control group | Average serum Hcy concentration was 9.3 ± 3.16 μmol/L in JIA patients and 8.9 ± 2.42 μmol/L in healthy controls (p = 0.615) Vitamin B12 concentration was normal in patients and controls (p < 0.001) |
Henderson and Lovell. 1989 [34] | Total:28 | Cross-sectional | 36% of the patients have PEM 36% were considered not at nutritional risk 28% had some nutritional abnormalities |
Amancio et al. 2003 [35] | Total:64 JRA:41 Control:23 | cross-sectional with control group | Higher copper levels in male JRA than male in the control group: (p = 0.004) Significant relationships between disease activity and the number of inflamed joints with copper levels (p = 0.012 and p = 0.001, respectively) |
Mortensen et al. 1990 [36] | Total:38 | cross-sectional | Mean energy intakes were significantly below the RDI in the systemic (P = 0.01) and PA(P = 0.001) groups Mean intakes of calcium and zinc were below the RDI of 100% in the PA group(P = 0.001) The mean intakes for iron, thiamine, niacin equivalents, riboflavin, Vitamins C and A were all above the RDI in each group |
Dağdeviren-Çakır et al. 2016 [37] | Total:217 JIA in active disease: 64 JIA in remission: 53 Healthy controls: 100 | cross-sectional case–control | Significantly higher levels of Serum 25(OH) vitamin D in healthy subjects compared to the patients (p < 0.01) No statistically significant correlation between vitamin D levels and the number of joints with active arthritis (r = 0.1, p = 0.4) and physician and family VAS assessments (r = 0.03/p = 0.77, r = 0.03/p = 0.78 respectively) |
Çomak et al. 2014 [38] | Total:47 | Retrospective study | A significant negative correlation between 25(OH) D levels and physician VAS, parent VAS and joint count (p = 0.001, p = 0.001, p = 0.02, respectively) A significant negative correlation between 25(OH)D levels and disease activity(p = 0.01, r = -0.37) |
Caetano et al. 2012 [39] | Total:77 JIA:42 Control:35 | Cross-section with controlled group | A significantly greater percentage of total body fat (p = 0.001) truncal fat (p = 0.011) in JIA girls compared with controls |
Pelajo et al. 2012 [9] | Total: 154 | Cross-section | No association between 25(OH)D levels and JADAS-27 (p = 0.97) Significant associations between JADAS-27 and JIA subtype (p = 0.003), and ethnicity (p = 0.006) |