Parameters | n | Control period | 12VT | 20VT | 12VT vs Control | 20VT vs Control | 20VT vs 12VT |
|---|
6MWT ITT (m) | 34 | 406 (391, 422) | 407 (391, 423) | 429 (413, 446) | 0 (− 12, 13) | 23 (6, 39)** | 22 (9, 36)††|
6MWT PPA (m) | 29 | 421 (404, 438) | 422 (405, 439) | 444 (427, 462) | 1 (−12, 15) | 23 (6, 41)* | 22 (8, 37)††|
10MWT (m/s) | 25 | 2.27 (2.12, 2.42) | 2.36 (2.21, 2.51) | 2.46 (2.29, 2.62) | 0.09 (− 0.05, 0.26) | 0.18 (0.00, 0.37)* | 0.10 (− 0.06, 0.25) |
- 6MWT 6-minute walk test; 10MWT 10-m walk test; 12VT assessment after 12 weeks of side-alternating vibration therapy; 20VT assessment after 20 weeks of side-alternating vibration therapy; ITT intention-to-treat analysis; PPA per-protocol analysis
- Data at each assessment are the adjusted means and 95% confidence intervals (CI), while differences between assessments are the adjusted mean differences and 95% CI; all values were derived from linear mixed models based on repeated measures including the participant’s GMFCS level, randomisation group (20 Hz / 25 Hz), and the baseline value of the outcome as a covariate
- p-values for statistically significant differences (at p < 0.05) between two given assessments are shown in bold; *p < 0.05 and **p < 0.01 for pairwise differences compared to the Control period; ††p < 0.01 for a difference between 12VT and 20VT
- n is the number of participants at baseline; the number of participants who completed a given assessment is provided in Additional file 1
